The presence of antiphospholipid antibodies is associated with thromboembolic events, thrombocytopenia and numerous pregnancy complications such as recurrent miscarriage, preeclampsia and HELLP syndrome. This condition is known as the antiphospholipid syndrome (APS). We describe a rare case of recurrent liver necrosis postpartum in two consecutive pregnancies of woman with systemic lupus erythematosus (SLE) and positive antiphospholipid antibodies (aPL) who underwent complete recovery.
Levine J , Branch D , Rauch J.The antiphospholipid syndrome . N Engl J Med2002; 346: 752-763 .
2.
Amant F , Spitz B , Arnout J , Van Assche FA.Hepatic necrosis and haemorrhage in pregnant patients with antiphospholipid antibodies . Lupus1997; 6: 552-555 .
3.
De Groot PG , Derksen RH.Pathophysiology of the antiphospholipid syndrome . Journal Thromb Haemost2005; 3: 1854-1860 .
4.
Tan EM , Cohen AS , Masi ATet al.The 1982 revised criteria for the classification of SLE . Arth Rheum1982; 25: 1271-1277 .
5.
Tincani A , Balestrieri G , Danieli Eet al.Pregnancy complications of the antiphospholipid syndrome . Autoimmunity2003; 36: 27-32 .
6.
Ozaras R , Mert A , Yilmaz MH , Kumbasar H , Tabak F , Ozturk R.Liver involvement in catastrophic antiphospholipid syndrome . Intern Med2004; 43: 346-347 .
7.
Fehr T , Cathomas G , Weber C , Fontana A , Schaffner A.Fetal loss, liver necrosis and acute lupus erythematosus in a patient with antiphospholipid syndrome . Lupus2001; 10: 576-579 .
