The development of three-dimensional in vitro human tissue models

Langer R. & Vacanti JP Tissue engineering. Science 1993; 260: 920-6.

Slivka SR , Landeen LK , Zeigler F. , Zimber MP & Bartel RL Characterization, barrier function, and drug metabolism of an in vitro skin model. Journal of Investigative Dermatology 1993; 100: 40-6.

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Triglia D. , Kidd I. , De Wever B. & Rooman R. Interlaboratory validation study of the Advanced Tissue Sciences' Skin2™ dermal model and MTT cytotoxicity assay kits. AATEX 1992; 1: 142-7.

Slivka S. , Stevens-Burns D. , Naughton G. & Bartel R. A novel method for colorimetric assessment of collagen matrix deposition in a three-dimensional dermal culture system. In Vitro Cellular and Developmental Biology 1991; 27: 159A.

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Slivka SR & Zeigler F. Use of an in vitro skin model for determining epidermal and dermal contributions to irritant responses. Journal of Toxicology - Cutaneous & Ocular Toxicology 1993; 12: 49-57.

Pirovano R. , Zaninelli P. , Noben J. , Logemann P. , Southee J. , Joller P. & Coquette A. A European interlaboratory evaluation study of an in vitro ocular irritation model (Skin2™ Model ZK1100) using 15 chemicals and three shampoos. ATLA 1993; 21: 81-8.

Osborne R. , Perkins MA , Roberts DA & Bruner LH Development of an in vitro assay for ocular irritancy assessments on aqueous incompatible substances (abstract). The Toxicologist 1992; 12: 296.

Slivka SR & Bartel RL Rapid estimation of collagen in a dermal model (letter to the editor). In Vitro Cellular Developmental Biology 1992; 28A: 690-2.

Contard P. , Jacobs II L. , Perlish JS & Fleischmajer R. Collagen fibrillogenesis in a three-dimensional fibroblast cell culture system. Cellular Tissue Research (in press).

Zeigler, FC , Landeen, L. Naughton, GK & Slivka, SR A tissue-engineered, three-dimensional human dermis to study extracellular matrix formation in wound healing. Journal of Toxicology - Cutaneous & Ocular Toxicology (in press).

Fleischmajer R. , MacDonald II ED , Contard P. & Perlish JS Immunochemistry of a keratinocytefibroblast co-culture model for reconstruction of human skin . Journal of Histochemistry and Cytochemistry 1993; 41: 1359-66.

Fleischmajer R. , Contard P. , Schwartz E. , MacDonald II ED & Sakai LY Elastin-associated microfibrils (10 nm) in a three-dimensional fibroblast culture. Journal of Investigative Dermatology 1991; 97: 638-43.

Yang JJ & Krueger AJ Evaluation of two commercial human skin cultures for in vitro percutaneous absorption. In Vitro Toxicology 1992; 5: 211-7.

Slivka SR Testosterone metabolism in an in vitro skin model. Cell Biology and Toxicology 1992; 8: 267-76.

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Triglia D. , Sherard Braa S. , Donnelly T. , Kidd I. & Naughton GK A three-dimensional human dermal model substrate for in vitro toxicological studies. In: Goldberg AM (ed.). Alternative Methods in Toxicology, Vol. 8. New York: MaryAnn Liebert, Inc. 1991: 351-362.

Contard P. , Jacobs II L. , Perlish JS & Fleischmajer R. Collagen fibrillogenesis in a three-dimensional fibroblast cell culture system. Cell and Tissue Research (In press).

Naughton BA , Sibanda B. , Azar L. & San Román J. Differential effects of drugs upon hematopoiesis can be assessed in long-term bone marrow cultures established on nylon screens. P.S.E.B.M. 1992 ; 199: 481-90.

Tjota A. , Rossi TM & Naughton BA Stromal cells derived from spleen or bone marrow support the proliferation of rat natural killer cells in long-term culture. P.S.E.B.M. 1992; 200: 431-41.

Landeen LK , Zeigler FC , Halberstadt C. , Cohen R. & Slivka SR Characterization of human dermal replacement. Wounds 1992; 4: 167-75.

Hansbrough JF , Doré C. & Hansbrough WB Clinical trials of a living dermal tissue replacement placed beneath meshed, split-thickness skin grafts on excised burn wounds. Journal of Burn Care and Rehabilitation 1992; 13: 519-29.

Freed LE , Marquis JC , Nohris A. , Mikos AG , Ammanual J. & Langer R. Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers. Journal of Biomedical Materials Research 1993; 27: 11-23.

Donnelly TA , Destandau P. , Allen R. , Edwards SM & Rheins LA An in vitro skin model for the study of collagen matrix deposition by fibroblasts. Abstracts. Journal of Investigative Dermatology 1993; 100: 551.

Edwards SM , Donnelly TA , Sayre RA & Rheins LA Quantitative in vitro assessment of phototoxicity using a human skin model, Skin2™. Journal of Photodermatology, Photoimmunology Photomedicine 1992 (in press).