World Health Organisation.Informal consultation on planning strategy for the prevention of pesticide poisoning. Geneva, 25-29 November 1985. WHO/VBC/86.926. Geneva: WHO, 1986.
2.
World Health Organisation.Public Health impact of pesticides used in agriculture. Geneva: WHO, 1990.
3.
Jeyaratnam J.1984 and occupational health in developing countries . Scandinavian Journal of Work Environment and Health1985; 11: 229-34.
4.
Jeyaratnam J.Pesticide poisoning: a major global health problem . World Health Statistics Quarterly1990; 43: 139-44.
5.
Johnson, M.K.Personal communication, 1992.
6.
Dale HH, Feldberg W. & Vogt M.Release of acetylcholine at voluntary motor nerve endings. Journal of Physiology1936; 86: 353-80.
7.
Bowman WC, Gibb AJ, Harvey AL & Marshall IGPrejunctional actions of cholinoceptor agonists and antagonists and of anticholinesterase drugs. In: Kharkevich DA (ed.). Handbook of Experimental Pharmacology. Berlin, Springer-Verlag, 1986; 79: 142-70.
8.
Csillik B.Functional structure of the post-synaptic membrane in the myoneural junction . Akademia Kiado. Budapest , 1965.
9.
Mathews-Bellinger J. & Saltpeter MMDistribution of acetylcholine receptors at frog neuromuscular junctions with a discussion of some physiological implications. Journal of Physiology1978; 279: 197-217.
10.
Fertuck HC & Saltpeter MMQuantitation of junctional and extra-junctional acetylcholine receptors by electron microscope autoradiography after 125 I-alpha-bungarotoxin binding at mouse neuromuscular junctions. J. Cell Biol.1976; 69: 144-58.
11.
Saltpeter MM , Kasprzak H., Feng H. & Fertuck H.End-plates after esterase inactivation in vivo: correlation between esterase concentration, functional response and fine structure. Neurocytology1979; 8: 95-115.
12.
Boyd IA & Martin ARThe end-plate potential in mammalian muscle. Journal of Physiology (London). 1956; 132: 74-91.
13.
Liley AWAn investigation of spontaneous activity at the neuromuscular junction of the rat. Journal of Physiology1956; 132: 650-66.
14.
Bowman WC & Rand MJTextbook of Pharmacology, 2nd edn. Blackwell Scientific Publications, London , 1980.
15.
Besser RR, Gutmann L., Dillmann U., Weilamann LS & Hopf HCEnd-plate dysfunction in acute organophosphate intoxication. Neurology1989; 39: 561-7.
16.
Masland RL & Wigton RSNerve activity accompanying fasciculations produced by prostigmine. Journal ofNeurophysiology1940; 3: 269-75.
17.
Burns BD & Paton Wdm.Depolarization of the motor end-plate by decamethonium and acetylcholine . Journal of Physiology (London) 1951 ; 115: 41-73.
18.
Thesleff S.Motor end-plate "desensitization" by repetitive nerve stimulation. Journal of Physiology ( London) 1959; 148: 659-64.
19.
Katz B. & Miledi R.The binding of acetylcholine to receptors and its removal from the synaptic cleft. Journal of Physiology1973 ; 231: 549-74.
20.
Lorot C.Les combinations de la cresote dans le traitement de la tuberculose pulmonaire. ThesisParis 1899. Cited by Johnson MK, in Organophosphorus esters causing delayed neurotoxic effects. Arch Toxicol1975; 34: 259-88.
21.
Smith MI & Elvove E.Pharmacological and chemical studies of the cause of so-called Ginger-Paralysis: Preliminary Report, Public Health Rep1930 ; 45: 1703-16.
22.
Smith MI, Elvove E. & Frazier WHPharmacological action of certain phenol esters with special reference to the etiology of so-called Ginger-Paralysis: Second Report. Public Health Rep1930; 45: 2509-24.
23.
Koelle GB & Gilman A.Anticholinesterase drugs. Journal of Pharmacology and Experimental Therapeutics1949; 95: 166; 216.
24.
Smith MI & Lillie RDHistopathology of triorthocresyl-phosphate poisoning: etiology of so-called ginger paralysis. Archives of Neurology and Psychiatry1931; 26: 976-92.
25.
Earl CJ & Thompson Rhs.Cholinesterase levels in the nervous system in tri-ortho-cresyl phosphate poisoning. BritishJournal of Pharmacology1952; 7: 685-94.
26.
Bidstrup PL , Bonnell JA & Beckett AGParalysis following poisoning by a new organic phosphorus insecticide (mipafox ). Report on two cases. British Medical Journal1953; 1: 1069-72.
27.
Bidstrup PL & Bonnell JAAnticholinesterases: paralysis in man following poisoning by cholinesterase inhibitors. Chemistry and Industry1954; 24: 674-6.
Gaines TBThe acute toxicity of pesticides to rats. Toxicology and Applied Pharmacology1960; 2: 88-99.
30.
Durham WF, Gaines TB & Hayes WJ Jnr.Paralytic and related effects of certain organic phosphorus compounds. Archives of IndustrialHealth1956 ; 13: 326-30.
31.
Davies DR, Holland P. & Rumens MJThe relationship between the chemical structure and neurotoxicity of allyl organophosphorus compounds. BritishJournal of Pharmacology1960; 15: 271-78.
32.
Witter RF & Gaines TBRelationship between depression of brain or plasma cholinesterase and paralysis in chickens caused by certain organic phosphorus compounds. Biochem Pharmacol1963; 12: 1377-86.
33.
Ariens AT, Cohen EM, Meeter E. et al. Reversible necrosis in striated muscle fibres of the rat after severe intoxication with various cholinesterase inhibitors. Industrial MedicineSurgery1968; 37: 532.
34.
Ariens AT, Meeter E., Wolthuis OL & van Benthem RMJ.Reversible necrosis at the end-plate region in striated muscles of the rat poisoned with cholinesterase inhibitors. Experientia1969; 25: 57-9.
35.
Preusser, HJDie Ultrastruktur der motorischen Endplatte in Zwerchfell der Ratte und Veranderungen nach Inhibierung der Acetylcholinesterase . Zeitschrift fur Zellforschung und mikroskopische Anatomie1967; 80: 436-45.
36.
Fischer G. Inhibierung und Restitution derAzetylcholinesterase an der motorischen Endplatte im Zerchfell der Ratte nach Intoxikation mit Soman. Histochemistry1968; 16: 144-9.
37.
Feng H., Rogers AW & Saltpeter MMRecovery of esterases at muscle endplates inactivated by DFP. J Cell Biol1973; 59: 98a.
Fenichel GM , Kibler WB, Olson WH, Dettbarn WDChronic inhibition of cholinesterase as a cause of myopathy. Neurology1972; 22: 1026-1033.
40.
Hughes JN, Knight R., Brown Rfr & Marrs TCEffects of experimental sarin intoxication on the morphology of the mouse diaphragm: a light and electron microscopical study. International Journal of Experimental Pathology1991; 72: 195-209.
41.
Engel AG, Lambert EH & Santa T.Study of long term anticholinesterase therapy. Effects on neuromuscular transmission and motor end-plate fine structure. Neurology1973; 23: 1273-81.
42.
Lytle RBIncreased synaptic area of neuromuscular junction in neostigmine treated rats . Anatomical Record1970; 166: 339.
43.
Laskowski MB & Dettbarn WDThe pharmacology of experimental myopathies . Annual Review of Pharmacology and Toxicology1971; 17: 387-409.
44.
Johnson MKThe primary biochemical lesion leading to the delayed neurotoxic effects of some organophosphate esters. Journal of Neurochemistry1974; 23: 785-9.
45.
Abou-Donia MBOrganophosphorus ester induced delayed neurotoxicity . Annual Review of Pharmacology and Toxicology1981; 21: 511-48.
46.
Shatig SA, Milhovat AT & Gonycki WAFine structure of human muscle in neurogenic atrophy. Neurology (Minneapolis)1967; 17: 934.
47.
Wecker L. & Dettbarn WDParaoxon induced myopathy; muscle specificity and acetylcholine involvement. ExperimentalNeurology1976; 51: 281-91.
Perron R. & Johnson BBInsecticide poisoning. New England Journal of Medicine1969; 281: 274-5.
54.
Mahieu P., Hassoun A., van Bist R., Lauwerys R. & Deheneffe Y.Severe and prolonged poisoning by fenthion: significance of the determination of the anticholinesterase capacity of plasma. Journal of Toxicology and Clinical Toxicology1982; 19: 425-32.
55.
Wadia RS, Bhirud RH, Gulvani AV & Amin RBNeurological manifestations of three organophosphate poisons. Indian Medical Research1977; 66: 460-8.
56.
De Rueck J & Willems J.Acute parathion poisoning: myopathic changes in the diaphragm. Journal ofNeurology1975 ; 206: 309-14.
57.
Wecker L., Mrak RE & Dettbarn WDEvidence of necrosis in human intercostal muscle following inhalation of an organophosphate insecticide. Toxicology and Applied Pharmacology1986; 6: 172-4.
58.
Senanayake N. & Karalliedde L.Neurotoxic effects of organophosphorus insecticides: an intermediate syndrome. New England Journal of Medicine1987; 316: 761-3.
59.
Berry WK & Lovatt-Evans C.Cholinesterase and neuromuscular block. Journal of Physiology1951; 115: 46P-47P.
60.
Gutmann L. & Besser R.Organophosphate intoxication: pharmacologic clinical and therapeutic considerations . Neurology1990; 10: 46-51.
61.
Li TH & Ting YCStudies on the neuromuscular junction XXI. Responses of cat muscles to acetylcholine during Wedensky inhibition and post-tetanic facilitation . Chinese Journal of Physiology1941; 16: 1-8.
62.
Douglas WW & Paton Wdm.The mechanism of motor endplate depolarization due to a cholinesterase inhibiting drug. Journal of Physiology ( London) 1954; 124: 325-44.
63.
Besser R., Gutman L. & Weilemann LSInactivation of end-plate acetylcholinesterase during the course of organophosphate intoxications. Archives of Toxicology1989 ; 63: 412-5.
64.
Couteaux R.Morphological and cytochemical observations on the post-synaptic membrane at motor endplates and ganglionic synapses. Experimental Cell Research (Suppl)1958; 5: 294-322.
65.
Dettbarn WDPesticide induced muscle necrosis: mechanisms and prevention. Fundamentals of Applied Toxicology1984; 4: 518-526.
66.
Ferry CB & Townsend HEAnticholinesterase induced myopathy and changes in creatine kinase in mice . Journal of Physiology1986; 373: 29P.
67.
Gupta RG, Patterson GT & Dettbarn WDAcute tabun toxicity. Biochemical and histochemical consequences in brain and skeletal muscles of rat. Toxicology1987 ; 46: 329-41.
68.
Gupta RG & Dettbarn WDIso-OMPA induced potentiation of soman toxicity in rat. Archives of Toxicology1987; 61: 58-62.
69.
Hertzberg O. , Moult J. & James Mng.Calcium binding to skeletal muscle troponin C and the regulation of muscle contraction. Ciba Foundation Symposium1985; 122: 120-144.
70.
Csillik B. & Savay G.Release of calcium in the myoneural junction. Nature1963; 184: 399-400.
71.
Leonard JP & Saltpeter MMAgonist induced myopathy at the neuromuscular junction is mediated by calcium. Journal ofCell Biology1979; 82: 811-9.
72.
Marrs TC, Bright JE, Inns RH & Tuckwell NJHistochemically demonstrated calcium influx into mouse diaphragms induced by sarin. Toxicologist1990; 10: 132.
73.
Inns RH, Tuckwell NJ, Bright JE & Marrs TCHistochemical demonstration of calcium accumulation in muscle fibres after experimental organophosphate poisoning. Human and Experimental Toxicology1990; 9: 245-50.
74.
Jenkinson DH & Nicholls JGContractures and permeability changes produced by acetylcholine in depolarized denervated muscle. Journal of Physiology (London) 1961 ; 159: 111-27.
75.
Miledi R., Parker I. & Schalow G.Calcium entry across the post-junctional membrane during transmitter action . Journal of Physiology (London ) 1977; 268: 32-3.
76.
Chang Hw K, Neumann E.Dynamic properties of isolated acetylcholine receptor proteins: release of calcium ions caused by acetylcholine binding . Proceedings of the National Academy of Sciences of the United States of America1976; 73: 3364-8.
77.
Rubsamen H. , Hess GP, Eldefrawi AT & Eldefrawi MEInteraction between calcium and ligand-binding sites of the purified acetylcholine receptor studies by use of a fluorescent lanthanide. Biochemical and Biophysical Research Communications1976; 68: 56-63.
78.
Tattersall Jeh.The acetylcholine receptor: effects of organophosphorus compounds and oximes. Human and Experimental Toxicology1992; 11: 559-60.
79.
Albuquerque EX, Deshpande SS, Kawabuchi M Aracavay Y, Idriss M, Rickett DL & Boyne AF. Multiple action of anticholinesterase agents on chemosensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning. Fundamentals of Applied Toxicology1985; 5: S182-S203.
80.
Orrenius S., McConkey DJ & Nicotera P.The role of calcium in cytotoxicity. In: Volans GN, Sims TSullivan FM, Turner P. eds Basic Science in Toxicology. Brighton; Taylor Francis, 1989, pp. 629-36.