The peripheral lymphocytes of 11 male and seven female workers occupationally exposed to textile dyes were studied for cytogenetic change. A significant increase in the frequency of chromosomal aberrations and sister chromatid exchanges were recorded regardless of the duration of the workers' exposure to the dyes.
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References
1.
Garner RC & Nutman CATesting of some azo dyes and their reduction products for mutagenicity using Salmonella typhimurium TA 1538. Mutation Research1977; 44: 9-19.
2.
Prival MJ , Bell SJ, Mitchell VD, Peripheral MD & Vaughan VLMutagenicity of benzidine and benzidine cengeuner dyes and selected mono-azo dyes in a modified Salmonella assay. Mutation Research1984; 136: 33-47.
3.
Somashekar RKMeiotic abnormalities induced by dye industry waste water in Chlorophytrum amanienese (Engler) . Cytologia1987; 52: 647-52.
4.
Docker A. , Wattie JM, Topping MD et al. Clinical and immunological investigations of respiratory disease in workers using reactive dyes. British Journal of Industrial Medicine1987; 44, 534-41.
5.
Moorhead PS , Nowell PG, Mellman WJ, Battips DM & Hungerford DAChromosome preparations of leucocyte cultures from human peripheral blood . Experimental Cell Research1960; 20: 613-16.
6.
Perry P. & Wolff S. NewGiemsa method for the differential staining of sister chromatids. Nature1974; 251: 156-8.
7.
Trotman (EREd).Dyeing and Chemical Technology of Textile Fibres. London: Macmillan Press, 1983.
8.
Dipaolo JA & Popescu NCRelationship of chromosome changes to neoplastic cell transformation. American Journal of Pathology1976; 85: 709-38.
9.
Obe G. , Gobel D., Engeln H., Herha J. & Natarajan AIChromosomal aberrations in peripheral lymphocytes of alcoholics. Mutation Research1980; 73: 377-86.
10.
Sorsa M. , Maki, Paakanen J. & Vainio H.Identification of mutagen exposures in the rubber industry by the sister chromatid exchange methodCytogenetics and Cell Genetics1982 ; 33: 68-73.
11.
Rom WN , Livingston GK, Casey KR et al. Sister chromatid exchange frequency in asbestos workers. Journal of the National Cancer Institute1983; 70: 45-8.
12.
Nagaya T. , Ishikawa N. & Hata H.Sister chromatid exchange analysis in lymphocytes of workers exposed to hexavalent chromium. British Journal of Industrial Medicine1989; 46: 48-51.