We describe a case of severe oxprenolol poisoning (8 g overdose) where restoration of normal blood pressure depended critically on high-dose glucagon infusion after several bolus injections of glucagon had failed. We stress the importance of infusion delivery of glucagon in severe beta-blocker poisoning.
Get full access to this article
View all access options for this article.
References
1.
Illingworth RNGlucagon for beta-blocker poisoning. Practioner1979; 223: 683-5.
2.
Kosinski EJ, Stein N., Malindzar GS Jr & Boone E.Glucagon and Propranolol (Inderal) toxicity. New England Journal of Medicine1971; 285: 1325.
3.
Ward DE & Jones B.Glucagon and beta-blocker toxicity. British Medical Journal1976; 2: 151.
4.
Khan A. & Muscat-Baron JMFatal oxprenolol poisoning. British Medical Journal1977; 1: 552.
5.
Lagerfelt J. & Matell G.Attempted suicide with 5.1G of propranolol. A case report. Acta Medicine Scandinavia1976; 199: 517.
6.
Editorial. Death from an overdose of Oxprenolol. Pharmaceutical Journal1972; 208: 143.
7.
Frishman W.Clinical pharamacology of the new beta-adrenergic blocking drugs. Part 1. Pharmacodynamic and pharmacokinetic properties. American Heart Journal1979; 97: 663.
8.
Buiuhsohn A. , Eisenberg ES, Jacob H. et al. Seizures and intraventricular conduction defect in propranolol poisoning (a report of two cases). Annals of Internal Medicine1979; 91: 860-2.
