British Toxicology Society Working Party Special Report.A new approach to the classification of substances and preparation on the basis of their acute toxicity . Human Toxicology1984; 3: 85-92.
2.
Commission Directive (1983 ). Commission Directive of 29 July 1983 adapting to technical progress for the fifth time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Official Journal of the European CommunitiesL2571983; 26.
3.
Oecd. In OECD Guidelines for Testing of Chemicals, Section 4OECD, Paris, 1981.
4.
ReinhardtChA, Bosshard E & Schlatter Ch. Irritation testing of skin and mucous membranes . Food and Chemical Toxicology1985 ; 23: 1-336.
5.
Rhodes C. , Pemberton MA, Scott RC & Oliver Gja.Prevalence of toxic responses in acute toxicity assessments of industrial chemicals. Human Toxicology, 1986; 5: 409-10.
6.
Pemberton MA , Rhodes C., Doe J. & Oliver Gja.Prevalence and prediction of acute skin and eye irritation. Society ofToxicology1987; in press.
7.
Gfeller W. , Kobel W. & Seifert G.Overview of animal test methods for skin irritation. Food and Chemical Toxicology1985; 23: 165-8.
8.
Kobel W. & Gfeller W.Distribution of eye irritation scores of industrial chemicals. Food and Chemical Toxicology1985; 23: 311-2.
9.
ECETOC Monograph No. 8 (1986). Structure-activity relationships in toxicology and ecotoxicology: an assessment .
10.
Oliver Gja & Pemberton MAAn in vitro epidermal slice technique for identifying chemicals with the potential for severe cutaneous effects. Food and Chemical Toxicology , 1985; 23: 229-32.
11.
Purchase Ifhp , Conning DM, Balls M., Rhodes C., Davies DS & Bridges JMInternational Conference on Practical In vitro Toxicology. Food and Chemical Toxicology1986 ; 24: 449-527.
12.
Parish WERelevance of in vitro tests to in vivo acute skin inflammation; potential in vitro applications of skin keratome slices, neutrophils, fibroblasts, mast cells and macrophages . Food and Chemical Toxicology1985; 23: 275-85.
13.
Parish WEAbility of in vitro (cornea) injury-eye organ and chorioallantoic membrane tests to represent histopathological features of acute eye inflammation . Food and Chemical Toxicology1985; 23: 215-27.
14.
Philips L. , Steinberg M., Maibach HI & Akers WAA comparison of rabbit and human skin responses to certain irritants . Toxicology and Applied Pharmacology1972 ; 21: 369-82.
15.
Davies RE , Harper KH & Kynoch SRInterspecies variaton in dermal reactivity. Journal of the Society of Cosmetic Chemists1972; 23: 371-2.
16.
Sams WM & Epstein JHExperimental production of drug phototoxicity in guinea pigs, using sunlight . Journal of Investigative Dermatology1967 ; 48: 89-94.
17.
Forbes PD , Urbach F. & Davies REPhototoxicity testing of fragrance raw materials. Food and Cosmetics Toxicology1977; 15: 55-60.
18.
Marakawa F. , Nakayama Y. & Fukuda M.Sunlight and Man, p. 529. Tokyo: Tokyo Press, 1974.
19.
Williams SJChanging concepts of ocular irritation. Evaluation: pitfalls and progress . Food and Chemical Toxicology1985; 23: 189-93.
20.
Carter LM , Duncan G. & Rennie GKEffects of detergents on the ionic balance and permeability of isolated bovine cornea. Experimental Cell Research1973; 75: 200-6.
21.
Burton Abg , York M. & Lawrence RSThe in vitro assessment of severe eye irritants. Food and Cosmetics Toxicology1981; 19: 471-80.
22.
Nardone RM & Bradlaw JAToxicity testing with in vitro systems 1. Ocular tissue culture. Journal of Toxicology: Cutaneous and Ocular Toxicology1983 ; 2: 81-9.
23.
Price JB & Andrews IJThe in vitro assessment of eye irritancy using isolated eyes. Food and Chemical Toxicology1985; 23: 313-5.
24.
Muir CKThe comparative effects of proprietory antidandruff, adult and baby shampoos on rabbit serum . Toxicology Letters1983; 18: 227-30.
25.
Muir CKThe toxic effect of some industrial chemicals on rabbit serum in vitro compared with eye irritancy in vivo . Toxicology Letters1983; 19: 309-12.
26.
Muir CK , Flower C. & Van Abbe NJA novel approach to the search for in vitro alternatives to in vivo eye irritancy testing. Toxicology Letters1983; 18: 1-5.
27.
Scaife MCThe rabbit eye irritancy test-are there in vitro alternatives . Alternatives to Laboratory Animals1985 ; 12: 157-62.
28.
Swanston DWEye irritancy testing. In Animals and Alternatives in Toxicity Testing, eds M Balls, RJ Riddell & AN Warden , p. 327. London: Academic Press, 1983.
29.
Swanston DWAssessment of the validity of animal techniques in eye irritation testing . Food and Chemical Toxicology1985; 23: 169-73.
30.
Beckley JAComparative eye testing. Man vs. animal . Toxicology and Applied Pharmacology1965; 7: suppl. 2, 93-101.
31.
Calabrese EJOcular toxicity. In Principles of Animal Extrapolation, p. 400. New York : J. Wiley & Sons, 1983.
32.
Ballantyne B. & Swanston DWThe irritant potential of dilute solution of ortho-chlorobenzylidene malononitate (CS) on the eye and the tongue . Acta Pharmacologica et Toxicologica1973 ; 32: 266-77.
33.
Ballantyne B. & Swanston DWThe irritant effect of dilute solutions of dibenzoxazepine (CR) on the eye and tongue. Acta Pharmacologica et Toxicologica1974; 35: 412-23.
34.
Griffiths JF , Nixon GA, Bruce RB, Reer PJ & Bannan EADose-response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the eye. Toxicology and Applied Pharmacology1980; 55: 501-13.
35.
Jackson J. & Rutty DAOcular tolerance assessment- integrated tier policy. Food and Chemical Toxicology1985 ; 23: 309-310.
36.
Ulsamer AG , Wright PC & Osterberg PEA comparison of the effects of model irritants on anaesthetised and non-anaesthetised rabbit eyes. Toxicology and Appied Pharmacology1977; 41: 191-2.
37.
Ehlers N.Pharmacology of the conjunctival sac. In Drugs and Ocular Tissues , ed. S Dikstein, pp. 23-56, Basel : Karger, 1977.
38.
Cremer-Bartells G.Effects of drugs on corneal stroma. In Drugs and Ocular Tissues, ed. S Dikstein, pp. 102-27. Basel: Karger, 1977.
39.
Harrison JC , Karcioglu A. & Johnson MKResponse of leukopenic rabbits to pneumococeal toxin. Current Eye Research1983; 2: 705-6.
40.
Walker APA more realistic animal technique for predicting human eye response . Food and Chemical Toxicology1985; 23: 175-8.