The Effectiveness of a Cation Resin (Kayexalate) as an Adsorbent of Paraquat: Experimental and Clinical Studies

Abstract

1 The cation-exchange-resin Kayexalate^R has an adsorption capacity for paraquat 15 times greater than activated charcoal and 6 times greater than Adsorbin. The oral LD₅₀ of paraquat in rats rose 2.1 times by intragastric injection of Kayexalate.¹

2 In the present study, the survival rate of rats given Kayexalate or Adsorbin after paraquat administration was examined. Results of clinical studies on 22 patients are also presented.

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References

Takagi S. , Yamashita M. , Suga H. & Naito H. The effectiveness of cation exchange resin as an Adsorbent of paraquat both in vitro and in vivo. Veterinary and Human Toxicology 1983; 25: suppl. 1, 34-35.