The successful management of a case of quinine overdose with blindness is described. From a review of the literature, treatment of moderate poisoning with ingestion of < 10 g of quinine should consist of immediate and thorough gastric lavage, forced acid diuresis, immediate bilateral stellate ganglion blockage repeated if there is clinical improvement in vision. With a larger overdose or when coma or convulsions occur haemodialysis, peritoneal dialysis or preferably haemoperfusion should be considered.
Bricknell, P.P., Middleton, H.G., Hollingsworth, A. & Evans, E.M.L. (1967). Stellate ganglion block in the treatment of total blindness due to quinine. Br. Med. J., iv, 400-401.
3.
Burrows, A.W., Hambleton, G., Hardman, M.J.Wilson, B.D.R. (1972). Quinine intoxication in a child treated by exchange transfusion. Arch. Dis. Child, 47, 304-305.
