1 A woman survived ingestion of 32 g nalidixic acid despite developing lactic acidosis, hyperglycaemia, convulsions and abnormal behaviour.
2 The maximum recorded plasma concentration of nalidixic acid was 185 mg/l and the elimination half-life was 3.2 h.
3 Carboxy-nalidixic acid was demonstrated in the plasma.
4 Previously reported cases of nalidixic acid overdosage are reviewed.
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