At the request of Sage Publishing and the Journal Editor, the following article has been retracted:
Wang Z, Shan Y, Yang Y, Wang T, Guo Z. MicroRNA-155 is upregulated in the placentas of patients with preeclampsia and affects trophoblast apoptosis by targeting SHH/GLi1/BCL2. Human & Experimental Toxicology. 2021;40(3):439-451. doi:10.1177/0960327120954252
Sage Publishing was made aware that this article may have been submitted with third-party involvement. We did not receive a response from the authors when we attempted to contact them for comment.
This article has been retracted due to our unresolved concerns on the authenticity of the authorship.
The authors did not respond when notified of this retraction.
References
1.
RedmanCWStaffAC. Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity. Am J Obstet Gynecol2015; 213: S9-e1, S9–11.
2.
El-SayedAAF.Preeclampsia: a review of the pathogenesis and possible management strategies based on its pathophysiological derangements. Taiwan J Obstet Gynecol2017; 56: 593–598.
3.
HuppertzB. The critical role of abnormal trophoblast development in the etiology of preeclampsia. Curr Pharm Biotechnol2018; 19: 771–780.
4.
AbbasYOefnerCMPolacheckWJ, et al.A microfluidics assay to study invasion of human placental trophoblast cells. J R Soc Interface2017; 14: 20170131.
5.
ShanNXiaoXChenY, et al.Expression of DAB2IP in human trophoblast and its role in trophoblast invasion. J Matern Fetal Neonatal Med2016; 29: 393–399.
6.
LiuPLLiuWLChangJM, et al.MicroRNA-200c inhibits epithelial-mesenchymal transition, invasion, and migration of lung cancer by targeting HMGB1. PLoS One2017; 12: e0180844.
7.
BuQYouFPanG, et al.MiR-125b inhibits anaplastic thyroid cancer cell migration and invasion by targeting PIK3CD. Biomed Pharmacother2017; 88: 443–448.
8.
LeeDCRomeroRKimJS, et al.miR-210 targets iron-sulfur cluster scaffold homologue in human trophoblast cell lines: siderosis of interstitial trophoblasts as a novel pathology of preterm preeclampsia and small-for-gestational-age pregnancies. Am J Pathol2011; 179(2): 590–602.
9.
HarapanHFitraFIchsanI, et al.The roles of microRNAs on tuberculosis infection: Meaning or myth?Tuberculosis (Edinb)2013; 93(6): 596–605.
10.
LuoSCaoNTangY, et al.Identification of key microRNAs and genes in preeclampsia by bioinformatics analysis. PLoS One2017; 12: e0178549.
11.
BoundsKRChiassonVLPanLJ, et al.MicroRNAs: new players in the pathobiology of preeclampsia. Front Cardiovasc Med2017; 4: 60.
12.
SalomonCGuanzonDScholz-RomeroK, et al.Placental exosomes as early biomarker of preeclampsia: potential role of exosomal MicroRNAs across gestation. J Clin Endocrinol Metab2017; 102: 3182–3194.
13.
WahidFShehzadAKhanT, et al.MicroRNAs: synthesis, mechanism, function, and recent clinical trials. Biochim Biophys Acta2010; 1803(11): 1231–1243.
14.
PinelesBLRomeroRMontenegroD, et al.Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am J Obstet Gynecol2007; 196(3): 261.e1–261.e2616.
15.
EnquobahrieDAAbetewDFSorensenTK, et al.Placental microRNA expression in pregnancies complicated by preeclampsia. Am J Obstet Gynecol2011; 204(2): 178.e12–178.e1.78E21.
16.
LaganàASVitaleSGSapiaF, et al.miRNA expression for early diagnosis of preeclampsia onset: Hope or hype?J Matern Fetal Neonatal Med2018; 31(6): 817–821.
17.
LiuSXieXLeiH, et al.Identification of key circRNAs/lncRNAs/miRNAs/mRNAs and pathways in preeclampsia using bioinformatics analysis. Med Sci Monit2019; 25: 1679–1693.
18.
ZhangYDiaoZSuL, et al.MicroRNA-155 contributes to preeclampsia by down-regulating CYR61. Am J Obstet Gynecol2010; 202(5): 466.e1–466.e4667.
19.
KatohYKatohM. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant Hedgehog signaling activation. Curr Mol Med2009; 9: 873–886.
20.
ZengXJuD. Hedgehog signaling pathway and autophagy in cancer. Int J Mol Sci2018; 19: 2279.
21.
PetrovaRJoynerAL. Roles for Hedgehog signaling in adult organ homeostasis and repair. Development2014; 141: 3445–3457.
22.
RishikayshPDevKDiazD, et al.Signaling involved in hair follicle morphogenesis and development. Int J Mol Sci2014; 15: 1647–1670.
23.
LiuZXuJHeJ, et al.A critical role of autocrine sonic Hedgehog signaling in human CD138+ myeloma cell survival and drug resistance. Blood2014; 124: 2061–2071.
24.
ChenTHePTanY, et al.Biomarker identification and pathway analysis of preeclampsia based on serum metabolomics. Biochem Biophys Res Commun2017; 485: 119–125.
25.
LiLLuoJWangB, et al.MicroRNA-124 targets flotillin-1 to regulate proliferation and migration in breast cancer. Mol Cancer2013; 12: 163.
26.
TakaiHKondohEMogamiH, et al.Placental sonic Hedgehog pathway regulates foetal growth via insulin-like growth factor axis in preeclampsia. J Clin Endocrinol Metab2019. DOI: 10.1210/jc.2019-00335.
27.
ZhanMSunXLiuJ, et al.Usp7 promotes medulloblastoma cell survival and metastasis by activating Shh pathway. Biochem Biophys Res Commun2017; 484: 429–434.
28.
QuarantaRPelulloMZemaS, et al.Maml1 acts cooperatively with Gli proteins to regulate sonic Hedgehog signaling pathway. Cell Death Dis2017; 8: e2942.
29.
BohnenpollTWitternABMamoTM, et al.A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet2017; 13: e1006951.
30.
LiuXLiMPengY, et al.miR-30c regulates proliferation, apoptosis and differentiation via the Shh signaling pathway in P19 cells. Exp Mol Med2016; 48: e248.
31.
TongWQiuLQiM, et al.GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism. J Cell Biochem2018; 119: 3641–3652.
32.
PanYBGongYRuanHF, et al.Sonic Hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth. Cell Death Dis2015; 6: e1653.
33.
AwamlehZGloorGBHanVKM. Placental microRNAs in pregnancies with early onset intrauterine growth restriction and preeclampsia: potential impact on gene expression and pathophysiology. BMC Med Genomics2019; 12: 91.
34.
GanLLiuZWeiM, et al.MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. Medicine (Baltimore)2017; 96: e7515.
