Peter Dupré, 'Thudichum and Dupré - brothers-in-law', Journal of the Royal Society of Medicine, lxxxvi (1993), 417-20. The author, a second cousin of Thudichum's children, provides more personal details than his obituary: Anonymous, 'J.L.W. Thudichum', British Medical Journal, ii ( 1901 ), 726.
2.
Dupré, op. cit, 417.
3.
Henry McIlwain , 'Thudichum and medical chemistry in the 1860s to 1880s', Proceedings of the Royal Society of Medicine, li (1958), 127-32.
4.
Ibid., 127.
5.
Ludwig Thudichum and August Dupré, A Treatise on the Origin, Nature and Varieties of Wine ( London, New York: Macmillan , 1872).
6.
Ludwig Thudichum, Cookery, its Art and Practice (London: Frederick Warne & Co., 1895).
7.
Dupré, op. cit, 418.
8.
Ludwig Thudichum, A Treatise on the Pathology of Urine including a Complete Guide to its Analysis (London: Churchill , 1858, 2nd edn 1877).
9.
Award of Hastings Gold Medal to Ludwig Thudichum, British Medical Journal, (2) (1864 ) 132-4.
10.
Ludwig Thudichum , A Treatise on Gall-stones; their Chemistry, Pathology and Treatment (London: Churchill, 1863).
11.
—, 'Pathology and treatment of gall-stones', British Medical Journal, ii ( 1859 ), 935.
12.
Robert S. Sparkman, 'The early development of gall-bladder surgery', British Medical Journal, (2) (1959), 753-4.
13.
Donald B. Tower, 'Johann Ludwig Wilhelm Thudichum', in The Founders of Neurology, compiled and edited by W. Haymaker and F. Schiller (Spinfield, IL: C. C. Thomas , 2nd edn, 1970), 285-8; 297-302; 302-6.
14.
Ludwig Thudichum , A Manual of Chemical Physiology, including its Point of Contact with Pathology (London, 1872).
15.
McIlwain, op. cit, 130.
16.
Ibid., 130.
17.
Davis Coakley , Irish Masters of Medicine ( Dublin: Town House, 1990), 149-56 and 230.
18.
Theodore L. Sourkes, 'How Thudichum came to study the brain' , Journal of the History of Neurosciences, ii (1993) 117-19.
19.
Tower, op. cit, 302.
20.
Ludwig Thudichum , Report of the Medical Officer of the Privy Council 1874, new series 1, appendix 5, 113-247 (London : Eyre & Spottiswoode HMSO).
21.
—, A Treatise on the Chemical Constitution of the Brain (London: Baillière, Tindall & Co., 1884, reprinted, with a new historical introduction by David L. Drabkin (Hamden, CT: Archon Books, 1962); hereafter Treatise).
22.
—, 'On chemical diseases of the brain and spinal cord, as conditioned by the chemical constitution of these organs', British Medical Journal, (2) (1883 ), 524-6.
—, Die chemische Konstitution des Gehirns des Menschen und der Tiere (Tübingen: Pietzcker, 1901). Grundzüge der anatomischen und klinischen Chemie ... (Berlin, 1886). Briefe über offentliche Gesundheitpflege ihre bisherigen Leistungen und heutigen Aufgaben (Tübingen, 1898).
38.
McIlwain, op. cit, 132.
39.
F.E. Boulton , 'Dr Charles Alexander MacMunn - discoverer of the cytochromes', Bulletin of the Royal College of Pathologists , no. 53 (January 1986), 8-10; C.S. Breathnach, 'Old masters' , Irish Journal of Medical Science, cxlvi (1977), 185-9.
40.
Ludwig Thudichum , Report of the Medical Officer of the Privy Council , 10 (1867), appendix 7, 227 (London: HMSO).
41.
William D. Halliburton , 'The chemistry of the tissues and organs', in Edward A.Schafer's Textbook of Physiology, Vol. I ( Edinburgh : Pentland, 1898- 1900 ), 80-140, 118.
42.
Michael Foster , Textbook of Physiology, Vol. I, part 1 (London: Macmillan, 1893), 123.
43.
Halliburton, op. cit, 119
44.
Arthur Gamgee , 'Haemoglobin', in Edward A.Schafer's Textbook of Physiology, Vol. I (Edinburgh: Pentland , 1898-1900), 185-260.
45.
Thudichum, British Medical Journal (1883), op. cit, 526.
46.
Ibid., 526.
47.
Treatise, op. cit, ix-x.
48.
Ibid., xi.
49.
McIlwain, op. cit, 131.
50.
G. Curson, 'The history of neurochemistry as revealed by the Journal of Neurochemistry' , Journal of Neurochemistry, lxi (1993), 780-6.
51.
L. Sokoloff , M. Reivich, C. Kennedy, M.H. Des Rosiers, C.S. Patlak, K.D. Pettigrew, O. Sakurada and M. Sinohara, 'The C deoxyglucose method for the measurement of local cerebral glucose utilisation: theory, procedure and normal values in the conscious and anesthetised rat', Journal of Neurochemistry , xxviii ( 1977), 897-916.
52.
Seymour, S. Kety, C.F. Schmidt, 'The nitrous oxide method for the quantitative estimation of cerebral blood flow in man: theory, procedure and normal values ', Journal of Clinical Investigation, xxvii (1948), 476-83.
53.
L. Sokoloff , R. Mangold, R.L. Wechsler, C. Kennedy and S. Kety, 'The effect of mental arithmetic on cerebral circulation and metabolism', Journal of Clinical Investigation , xxxiv ( 1985), 1101-8.
54.
P.E. Roland and L. Friberg, 'Localisation of cerebral areas activated by thinking', Journal of Neurophysiology, liii (1985), 1219-43.
55.
M.I. Posner , S.E. Petersen, P.T. Fox and M.E. Raichle, 'Localisation of cognitive operations in the human brain', Science, ccxl (1988), 1627-31.
56.
L. Rueckert , N. Lange, A. Partiot, I. Appollonio, I. Litvar, D. Le Bihan and J. Grafman, 'Visualising cortical activities during mental calculation with functional magnetic resonance imaging', Neuroimage, iii (1996), 97-103.
57.
Chance Britton , Y. Nakase, M. Bond, J.S. Leigh Jr and G. McDonald, 'Detection of 31P nuclear magnetic resonance signals in brain by in vivo and freeze-trapped assays', Proceedings National Academy of Sciences USA, lxxv (1978), 4925-9.
58.
George K. Radda, 'The use of NMR spectroscopy for the understanding of disease', Science, ccxxxiii (1986), 640-5.
59.
R.A. Kauppinen , S.R. Williams, A.L. Busza, and N. van Bruggen, 'Applications of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology', Trends in Neurosciences , xvi (1993), 88-95.
60.
Robert G. Shulman, 'Functional imaging studies: linking mind and basic neuroscience', American Journal of Psychiatry , clviii (2001), 11-20.
61.
Kendal Dixon, 'Some biochemical signposts in the progress of neurology', in The Chemistry of Life, edited by Joseph Needham (Cambridge: Cambridge University Press, 1970), 60-124, p. 89.
62.
Tower, op. cit, 300.
63.
Thudichum, Treatise, op. cit, ix.
64.
Horace, Odes, III, xxx, 1 (I have raised a monument more lasting than brass).