A group of 91 women attending the STD-clinic, Department of Dermato-venereology, Sahlgrenska Hospital, Gothenburg, were screened for EBV DNA and HPV DNA of the cervix with the PCR-technique. Presence of EBV DNA was demonstrated in 35 (38%) women and HPV DNA in 30 (33%) women. Fourteen (15%) women had both EBV DNA and HPV DNA present. Without the colposcope 20 of these women had macroscopic signs of HPV infection on the vulva and/or vagina and 71 had no signs of infection. Presence of EBV DNA was not correlated to clinical signs of HPV infection.
LorinczATempleGFKurmanRJonsonA BenettLancasterWD.Oncogenic association of specific human papillomavirus with cervical neoplasia. J Natl Cancer Inst1987;79:671–7.
2.
NäherHGissmanLFreeseUKPetzoldtDHelfrichS.Subclinical Epstein-Barr virus infection of both the male and female genital tract—indication for sexual transmission. J Invest Derm1992;98:791–3.
3.
SixbeyJWLemonSMPaganoJS.A second site for Epstein-Barr virus shedding: The uterine cervix. Lancet1986;ii:1122–4.
4.
WongSYSewellHFMacgregorJEWalkerF.Epstein-Barr virus—a possible link in the initiation of cervical carcinogenesis?Med Hypothesis1991;35:219–22.
5.
YoungLSSixbeyJW.Epstein-Barr virus and the epithelial cells: A possible role for the virus in the development of cervical carcinoma. Cancer Surveys1988;7:507–18.
6.
VoogEBolmstedtAOlofssonSRydWLöwhagenG-B.Human Papilloma Virus infection among women attending an STD clinic correlated to reason for attending, presence of clinical signs, concomitant infections and abnormal cytology. Acta Dermato Ven (Stockh)1995;75:75–8.
7.
RickstenASvenssonCWelinderCRymoL.Identification of sequences in Epstein-Barr virus DNA required for the expression of the second Epstein-Barr virus determined nuclear antigen in COS-1 cells. J Gen Virol1987;68:2407–12.
8.
BaerRBankierATDemingerPLDNA sequence and expression of the B 95–8-Epstein-Barr virus genome. Nature1984;310:207–11.
9.
ManosMMTingYWrightDKLewisAJBrokerTRWolinskySM.The use of polymerase chain reaction amplification for detection of genital human papillomaviruses. Cancer Cells1989;7:209–14.
10.
SaikiRKSharfSFallonaFEnzymatic amplification of -globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science1985;230:1350–4.
11.
NäherHPetzoldtD.Die Epstein-Barr Virus—Infektion—eine lympho- und epitheliotrope Infektion. Hautarzt1992;43:114–19.
12.
PoltnoyJAhronheimGAGhibuFClecnerBJoncasJH.Recovery of Epstein-Barr Virus from genital ulcers. N Engl J Med1984;311:966–8.
13.
EvanderMEdlundKBodenEComparison of a one-step and a two-step polymerase chain reaction with degenerate general primers in a population-based study of Human Papillomavirus Infection in young Swedish women. J Clin Microbiol1992;30:987–92.
14.
StrandARylanderEEvanderMWadellG.Genital human papillomavirus infection among patients attending an STD clinic. Genitourin Med1993;69:446–9.
15.
RohanTMannVMcLaughlinJPCR-detected genital papillomavirus infection: Prevalence and association with risk factors for cervical cancer. Int J Cancer1991;49:856–60.
16.
BauerHMTingYGreerCEGenital Human Papillomavirus Infection in female university students as determined by a PCR-based method. JAMA1991;265:472–7.
17.
VoogELöwhagenGBRickstenATernestenA.Demonstration of Epstein-Barr virus DNA in acetowhite lesions of the vulva. Int J STD AIDS1994:1;25–9.
18.
HördingUDaugaardSBockJE.Human Papillomavirus, Epstein-Barr virus and cervical carcinoma in Greenland. M J Gynecol Cancer1992;2:314–17.
19.
SchönHJSchurzBMarzRKnoglerWKubistaE.Screening for Epstein-Barr and human cytomegalovirus in normal and abnormal cervical smears by fluorescent in situ cytohybridization. Arch Virol1992;125:205–14.
