Six homosexual men with a diagnosis of acquired immunodeficiency syndrome (AIDS)-related complex (ARC- CDC IVA/C2) were assessed with a series of neuropsychological and psychiatric tests prior to commencing treatment with zidovudine and again after 5–6 months. Significant improvements were seen in cognitive functioning, mental state and physical health at the second assessment.
McArthurJC. Neurologic manifestations of AIDS. Medicine1987; 66: 407–37
2.
CatalanJ.Psychosocial and neuropsychiatric aspects of HIV disease, J Psychosom Res1988; 32: 237–48
3.
NaviaBAJordanBDPriceRW. The AIDS dementia complex: I. Clinical features, Ann Neurol1986; 19: 517–24
4.
NaviaBAChoE-SPetitoCK. The AIDS dementia complex: II. Neuropathology. Ann Neurol1986; 19: 525–35
5.
NaviaBAPriceRW. The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection. Arch Neurol1987; 44: 65–9
6.
de GansJLangeJMADerixMMA, HIV antigen levels in cerebrospinal fluid in AZT treated serum antigen positive ARC/AIDS patients. Proceedings European Conference on Clinical Aspects of HIV Infection, Brussels, 1987
7.
YarchoanRThomasRVGrafmanJ. Long-term administration of 3′-azido-2′, 3′-dideoxythymidine to patients with AIDS-related neurological disease. Ann Neurol1988; 23 (Suppl.): S82–S87
8.
HelbertMPeddleBAGoldmeirDHarrisJRWPinchingJMannJ.Treatment of patients with AIDS and AIDS related complex with zidovudine. Proceedings European Conference on Clinical Aspects of HIV Infection, Brussels, 1987
9.
PizzoPAEddyJFalloonJ. The effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection. N Engl J Med1988; 319: 889–96
10.
SchmittFABigleyWBMcKinnisRLoguePEEvansRWDruckerJL. and the AZT Collaborative Working Group. Neuropsychological outcome of zidovudine (AZT) treatment of patients with AIDS and AIDS-related complex. N Engl J Med1988; 319: 1573–8
11.
ReinvangILundervoldFrolandSS. Effect of treatment of azidothymidine on neuropsychological function in patients with AIDS. Proceedings International Neuropsychological Society, Vancouver, 1989
