A 43-year-old male barber presented with 1 year history of a painful, itchy plaque on the dorsal hand. Microsporum canis was recovered from pus of the lesion. Serologic testing for human immunodeficiency virus (HIV) antibody was positive, with a CD4+ count of 81 cells per cubic millimeter. Invasive cutaneous Microsporum canis infection is uncommon and can be suggestive of HIV infection or other conditions of immunocompromise.
AlyRBergerT. Common superficial fungal infections in patients with AIDS. Clin Infect Dis1996; 22 Suppl 2(Suppl 2): S128–S132. DOI: 10.1093/clinids/22.supplement_2.s128.
2.
KaviarasanPKJaisankarTJThappaDM, et al.Clinical variations in dermatophytosis in HIV infected patients. Indian J Dermatol Venereol Leprol2002; 68: 213–216.
3.
RouzaudCHayRChosidowO, et al.Severe dermatophytosis and acquired or innate immunodeficiency: a review. J Fungi (Basel)2015; 2. DOI: 10.3390/jof2010004.
4.
ThakurRKalsiAS. Outbreaks and epidemics of superficial dermatophytosis due to trichophyton mentagrophytes complex and microsporum canis: global and indian scenario. Clin Cosmet Investig Dermatol2019; 12: 887–893. DOI: 10.2147/CCID.S220849.
5.
Muñoz-PèrezMARodriguez-PichardoACamachoF, et al.Extensive and deep dermatophytosis caused by Trichophyton mentagrophytes var. interdigitalis in an HIV-1 positive patient. J Eur Acad Dermatol Venereol2000; 14: 61–63. DOI: 10.1046/j.1468-3083.2000.00015.x.
6.
KwonKSJangHSSonHS, et al.Widespread and invasive Trichophyton rubrum infection mimicking Kaposi’s sarcoma in a patient with AIDS. J Dermatol2004; 31: 839–843. DOI: 10.1111/j.1346-8138.2004.tb00612.x.
7.
CostaJENevesRPDelgadoMM, et al.Dermatophytosis in patients with human immunodeficiency virus infection: clinical aspects and etiologic agents. Acta Trop2015; 150: 111–115. DOI: 10.1016/j.actatropica.2015.07.012.
8.
KershenovichRShermanSReiterO, et al.A unique clinicopathological manifestation of fungal infection: a case series of deep dermatophytosis in immunosuppressed patients. Am J Clin Dermatol2017; 18: 697–704. DOI: 10.1007/s40257-017-0276-y.
9.
KöhlerJRHubeBPucciaR, et al.Fungi that infect humans. Microbiol Spectr2017; 5. DOI: 10.1128/microbiolspec.FUNK-0014-2016.
10.
WangR.HuangC.ZhangY., et al.Invasive dermatophyte infection: a systematic review. Mycoses2020; 64: 340–348. DOI: 10.1111/myc.13212.
11.
Brosh-NissimovTBen-AmiRAstmanN, et al.An outbreak of Microsporum canis infection at a military base associated with stray cat exposure and person-to-person transmission. Mycoses2018; 61: 472–476. DOI: 10.1111/myc.12771.
