Several factors such as genetic susceptibility, autoimmunity, hormones, infections, local trauma, urine, and occlusion have been speculated to play a role in the pathogenesis of lichen sclerosus. We report two male patients with lichen sclerosus around ‘ectopic’ urethral openings and the opposing surfaces of the penile shaft and scrotum, providing further evidence in support of urine and occlusion as contributing factors in the development of lichen sclerosus.
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2.
GuptaSMalhotraAKAjithC. Lichen sclerosus: role of occlusion of the genital skin in the pathogenesis. Indian J Dermatol Venereol Leprol2010; 76: 56–58.
3.
BunkerCB. Occlusion, urine and genital lichen sclerosus. Indian J Dermatol Venereol Leprol2012; 78: 367–368.
4.
Al-NiaimiFLyonC. Peristomal lichen sclerosus: the role of occlusion and urine exposure?Br J Dermatol2013; 168: 643–646.
