Restricted accessResearch articleFirst published online 2020-7
Multifunctional hydroxyapatite and hopeite coatings on SS254 by laser rapid manufacturing for improved osseointegration and antibacterial character: A comparative study
Orthopaedic metallic implant’s long-term success strongly depends upon the two main factors: osseointegration and antibacterial character. Bioceramic (hydroxyapatite and hopeite) coatings have been proven effective for getting strong osseointegration and antibacterial character. However, deterioration of bioceramic coatings during the implantation period can adversely affect its overall biological performance. To conquer this issue, this research work recommends an innovative process route of laser rapid manufacturing for depositing bioceramic (hydroxyapatite and hopeite) coatings with metallurgical bonding. Microstructure, phase composition, antibacterial efficacy and bioactivity were evaluated using scanning electron microscopy, X-ray diffraction, fluorescence-activated cell sorting technique and simulated body fluid immersion test. The promising results obtained from these characterizations and testing establish the new process route laser rapid manufacturing as an effective alternative to deposit multifunctional bioceramic (hydroxyapatite and hopeite) coatings on metallic prosthetic–orthopaedic implants.
KimYW. Surface modification of Ti dental implants by grit-blasting and micro-arc oxidation. Mater Manuf Process2010; 25: 307–310.
2.
DaiYXuMWeiJ, et al. Surface modification of hydroxyapatite nanoparticles by poly(l-phenylalanine) via ROP of l-phenylalanine N-carboxyanhydride (Pha-NCA). Appl Surf Sci2012; 258: 2850–2855.
3.
NingCQZhouY. In vitro bioactivity of a biocomposite fabricated from HA and Ti powders by powder metallurgy method. Biomaterials2002; 23: 2909–2915.
4.
LinLWangHNiM, et al. Enhanced osteointegration of medical titanium implant with surface modifications in micro/nanoscale structures. J Orthop Translat2014; 2: 35–42.
5.
KimKHRamaswamyN. Electrochemical surface modification of titanium in dentistry. Dent Mater J2009; 28: 20–36.
6.
ManganoFChambroneLVan NoortR, et al. Direct metal laser sintering titanium dental implants: a review of the current literature. Int J Biomater2014; 2014: 461534.
7.
StrnadGChirilaN. Corrosion rate of sand blasted and acid etched Ti6Al4V for dental implants. Proc Tech2015; 19: 909–915.
8.
FerrarisSBobbioAMiolaM, et al. Micro- and nano-textured, hydrophilic and bioactive titanium dental implants. Surf Coat Tech2015; 276: 374–383.
9.
GagglASchultesGMullerWD, et al. Scanning electron microscopical analysis of laser-treated titanium implant surfaces – a comparative study. Biomaterials2000; 21: 1067–1073.
10.
GrafSMullerFA. CO2-laser-assisted surface modification of titanium alloys for biomedical applications. J Ceram Sci Technol2014; 5: 281–286.
11.
HansMGachotCMullerF, et al. Direct laser interference structuring as a tool to gradually tune the wetting response of titanium and polyimide surfaces. Adv Eng Mater2009; 11: 795–800.
12.
ChenJUlerichJPAbelevE, et al. An investigation of the initial attachment and orientation of osteoblast-like cells on laser grooved Ti-6Al-4V surfaces. Mater Sci Eng C2009; 29: 1442–1452.
13.
DisegiJAEschbachL. Stainless steel in bone surgery. Injury2000; 31: D2–D6.
14.
WalczacJShahgaldiFHeatleyF. In vivo corrosion of 316L stainless-steel hip implants: morphology and elemental compositions of corrosion products. Biomaterials1998; 19: 229–237.
15.
AfonsoMLCAVillamil JaimesRFVAreasEPG, et al. The influence of albumin on the anodic dissolution of chromium present in UNS S31254 stainless steel in chloride environment. Colloids Surf A Physicochem Eng Asp2008; 317: 760–763.
16.
AfonsoMLCAVillamil JaimesRFVNascentePAP, et al. Surface characterization, electrochemical behavior and cytotoxicity of UNS S31254 stainless steel for orthopaedic applications. Mater Lett2015; 148: 71–75.
17.
YuJChuXCaiY, et al. Preparation and characterization of antimicrobial nano hydroxyapatite composites. Mater Sci Eng C2014; 37: 54–59.
18.
ParkJWParkKBSuhJY. Effects of calcium ion incorporation on bone healing of Ti6Al4V alloy implants in rabbit tibiae. Biomaterials2007; 28: 3306–3313.
19.
SridharTMArumugamTKRajeswariS, et al. Electrochemical behaviour of hydroxyapatite-coated stainless steel implants. J Mater Sci Lett1997; 16: 1964–1966.
20.
KhandelwalHSinghGAgrawalK, et al. Characterization of hydroxyapatite coating by pulse laser deposition technique on stainless steel 316 L by varying laser energy. Appl Surf Sci2013; 265: 30–35.
21.
YamaguchiMOishiHSuketaY. Stimulatory effect of zinc on bone formation in tissue culture. J Mater Sci Lett1987; 36: 4007–4012.
22.
EberleJSchmidmayerSErbenRG, et al. Skeletal effects of zinc deficiency in growing rats. J Trace Elem Med Biol1999; 13: 21–26.
23.
ChenDWaiteLCPierceWM. In vitro effects of zinc on markers of bone formation. Biol Trace Elem Res1999; 68: 225–234.
24.
ShibliSMAJayalekshmiAC. Development of phosphate interlayered hydroxyapatite coating for stainless steel implants. Appl Surf Sci2008; 254: 4103–4110.
25.
HerschkeLRottsteggeJLieberwirthI, et al. Zinc phosphate as versatile material for potential biomedical applications part 1. J Mater Sci Mater Med2006; 17: 81–94.
UoMSjorenGSundhA, et al. Cytotoxicity and bonding property of dental ceramics. Int J Appl Glass Sci2003; 19: 487–492.
28.
AttarNTamLEMcCombD. Mechanical and physical properties of contemporary dental luting agents. J Prosthet Dent2003; 89: 127–134.
29.
HoriuchiSAsaokaKTanakaE. Development of a novel cement by conversion of hopeite in set zinc phosphate cement into biocompatible apatite. Biomed Mater Eng2009; 19: 121–131.
30.
LinFHHsuYSLinSH, et al. The effect of Ca/P concentration and temperature of simulated body fluid on the growth of hydroxyapatite coating on alkali-treated 316L stainless steel. Biomaterials2002; 23: 4029–4038.
31.
KokuboTItoSSakkaS, et al. Formation of a high strength bioactive glass-ceramic in the system MgO-CaO-SiO2-P2O5. J Mater Sci1986; 21: 536–540.
32.
KokuboTHayashiTSakkaS, et al. Bonding between bioactive glasses, glass-ceramics or ceramics in a simulated body fluid. Yogyo-Kyokai-Hi1987; 95: 785–791.
33.
KokuboTKushitaniHSakkaS, et al. Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W3. J Biomed Mater Res1990; 24: 721–734.
AzaPNDGuitianFAzaSD. Bioactivity of wollastonite ceramics: in vitro evaluation. Scripta Metall Mater1994; 31: 1001–1005.
36.
LiuDM. Bioactive glass-ceramic: formation, characterization and bioactivity. Mater Chem Phys1994; 36: 294–303.
37.
AzaPNDLuklinskaZBAnseauMR, et al. Bioactivity of pseudowollastonite in human saliva. J Dent1999; 27: 107–113.
38.
AzaPNDLuklinskaZ. Effect of the glass-ceramic microstructure on its in vitro bioactivity. J Mater Sci Mater Med2003; 14: 891–898.
39.
AzaPNDLuklinskaZBAnseauM. Bioactivity of diopside ceramic in human parotid saliva. J Biomed Mater Res2005; 73B: 54–60.
40.
AlemanyMIVelasquezPCasa-LilloMA, et al. Effect of materials processing methods on the in vitro bioactivity of wollastonite glass-ceramic materials. J Non-Cryst Solids2005; 351: 1716–1726.
41.
TlotlengMAkinlabiEShuklaM, et al. Microstructures, hardness and bioactivity of hydroxyapatite coatings deposited by direct laser melting process. Mater Sci Eng C2014; 43: 189–198.
42.
AhmedAMhaedeMWollmannM, et al. Characteristics of sintered HA coating deposited by chemical method on AISI 316L substrate. Mater Des2015; 76: 9–17.
43.
SinghSMeenaVKSharmaM, et al. Preparation and coating of nano-ceramic on orthopaedic implant material using electrostatic spray deposition. Mater Des2015; 88: 278–286.
44.
LiHLiZXLiH, et al. Effect of the deposition temperature on corrosion resistance and biocompatibility of the hydroxyapatite coatings. Mater Des2009; 30: 3920–3924.
45.
BalaniKLahiriDKeshriAK, et al. The nano-scratch behavior of biocompatible hydroxyapatite reinforced with aluminum oxide and carbon nanotubes. JOM2009; 61: 63–66.
46.
LinJHCLiuMLJuCP. Structure and properties of hydroxyapatite-bioactive glass composites plasma sprayed on Ti64. J Mater Sci Mater Med1994; 5: 279–283.
47.
BallaVKDasMBoseS, et al. Laser surface modification of 316 L stainless steel with bioactive hydroxyapatite. Mater Sci Eng C2013; 33: 4594–4598.
RoyMBallaVKBandyopadhyayA, et al. Comparison of tantalum and hydroxyapatite coatings on titanium for applications in load bearing implants. Adv Eng Mater2010; 12: B637–B641.
50.
BandyopadhyayABallaVKRoyM, et al. Laser surface modification of metallic biomaterials. JOM2011; 63: 94–99.
51.
DasMBallaVKBasuD, et al. Laser processing of in-situ synthesized TiB-TiN reinforced Ti64 alloy composite coatings. Scr Mater2012; 66: 578–581.
52.
BallaVKBhatABoseS, et al. Laser processed TiN reinforced Ti64 alloy composite coatings. J Mech Behav Biomed Mater2012; 6: 9–20.
53.
BallaVKBandyopadhyayA. Laser processing of Fe based bulk amorphous alloy. Surf Coat Technol2010; 205: 2661–2667.
54.
DindaGPShinJMazumderJ. Pulse laser deposition of hydroxyapatite thin coatings on Ti64: effect of heat treatment on structure and properties. Acta Biomater2009; 5: 1821–1830.
55.
LynnAKDuQuesnayDL. Hydroxyapatite-coated Ti-6Al-4V part 1: the effect of coating thickness on mechanical fatigue behaviour. Biomaterials2002; 23: 1937–1946.
56.
ZhangXXiaoGJiaoY, et al. Facile preparation of hopeite coating on stainless steel by chemical conversion method. Surf Coat Technol2014; 240: 361–364.
57.
GeXLengYBaoC, et al. Antibacterial coatings of fluoridated hydroxyapatite for percutaneous implants. J Biomed Mater Res A2010; 95: 588–599.
58.
DasAShuklaM. Surface morphology and in vitro bioactivity of biocompatible hydroxyapatite coatings on medical grade S31254 steel by RF magnetron sputtering deposition. Trans IMF2017; 95: 276–281.
59.
SarithaKRajeshAManjulathaK, et al. Mechanism of antibacterial action of the alcoholic extracts of Hemidesmus indicus (L.) R. Br. ex Schult, Leucas aspera (Wild.), Plumbago zeylanica L., and Tridax procumbens (L.) R. Br. ex Schult. Front Microbiol2015; 6: 577.
60.
DasAShuklaM. Surface morphology, bioactivity, and antibacterial studies of pulsed laser deposited hydroxyapatite coatings on Stainless Steel 254 for orthopaedic implant applications. J Mater Des Appl2019; 233: 120–127.
61.
DasAShuklaM. Hydroxyapatite coatings on high nitrogen stainless steel by laser rapid manufacturing. JOM2017; 69: 2292–2296.
62.
DasAShuklaM. Pulsed laser-deposited hopeite coatings on titanium alloy for orthopaedic implant applications: surface characterization, antibacterial and bioactivity studies. J Braz Soc Mech Sci2019; 41: 214.
63.
BagherifardSHickeyDJde LucaAC, et al. The influence of nanostructured features on bacterial adhesion and bone cell functions on severely shot peened 316L stainless steel. Biomaterials2015; 73: 185–197.
64.
PuckettSDTaylorERaimondoT, et al. The relationship between the nanostructure of titanium surfaces and bacterial attachment. Biomaterials2010; 31: 706–713.
65.
YiWSunXNiuD, et al. In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid. J Asian Ceram Soc2014; 2: 210–214.
66.
KokuboTTakadamaH. How useful is SBF in predicting in vivo bone bioactivity?Biomaterials2006; 27: 2907–2915.
67.
ManHCChiuKYChengFT, et al. Adhesion study of pulsed laser deposited hydroxyapatite coating on laser surface nitrided titanium. Thin Solid Films2009; 517: 5496–5501.
68.
NeoMKotaniSNakamuraT, et al. A comparative study of ultrastructures of the interfaces between four kinds of surface-active ceramic and bone. J Biomed Mater Res1992; 26: 1419–1432.
