This case report describes an aneurysmal bone cyst in the maxilla of a young dog. It describes the clinical presentation, diagnostics, management, and successful outcome of this highly unusual case. Bone cysts are described as benign, cavitated lesions within bone that are lined by reactive tissues. There is no epithelial lining in the lesions. Bone cysts usually contain hemorrhage or serosanguinous fluid. They usually appear in the long bones, and present as a swelling with or without pain.
VerstraeteFJM. Oral pathology. In: SlatterDH, ed. Textbook of small animal surgery. 3rd ed. WB Saunders Co.; 2003:2638‐2651.
4.
VerstraeteFJZinBPKassPHCoxDPJordanRC. Clinical signs and histologic findings in dogs with odontogenic cysts: 41 cases (1995-2010). J Am Vet Med Assoc. 2011;239(11):1470‐1476. doi:https://doi.org/10.2460/javma.239.11.1470
5.
SoukupJWBellCM. The canine furcation cyst, a newly defined odontogenic cyst in dogs: 20 cases (2013-2017). J Am Vet Med Assoc. 2020;256(12):1359‐1367. doi:https://doi.org/10.2460/javma.256.12.1359
6.
ChamberlainTPVerstraeteFJM. Clinical behavior and management of odontogenic cysts. In: VerstraeteFJMLommerMJ, eds. Oral and maxillofacial surgery in dogs and cats. 1st ed.Elsevier; 2012: 481‐486.
7.
JordanRCKoutlasIRaubenheimerEvan HeerdenWFPWrightJM. Odontogenic and maxillofacial bone tumours. In: El-NaggarAKChanJKCGrandisJRTakataTSlootwegPJ, eds. WHO classification of head and neck tumours. IARC Press; 2017: 258‐260.
AroraSSPaulSAroraSKapoorV. Secondary jaw aneurysmal bone cyst (JABC)—a possible misnomer? A review of literature on secondary JABCs, their pathogenesis and oncogenesis. J Oral Pathol Med. 2014;43(9):647‐651. doi:https://doi.org/10.1111/jop.12132
LiuYZhouJShiJ. Clinicopathology and recurrence analysis of 44 jaw aneurysmal bone cyst cases: a literature review. Front Surg. 2021;8:678696. doi:https://doi.org/10.3389/fsurg.2021.678696
AroraSSGroverAKumarVVAroraS. Aneurysmal bone cyst of maxilla existing concurrently with a giant cell granuloma of mandible: a case report of an unusual presentation. J Indian Soc Pedod Prev Dent. 2012;30(4):340‐342. doi:https://doi.org/10.4103/0970-4388.108938
14.
RegeziJASciubbaJJJordanRC. Cysts of the jaw and neck. In: RegeziJASciubbiJJJordanRC, eds. Oral pathology-clinical pathologic correlations. 7th ed. Saunders Elsevier; 2017: 245‐258.
15.
ShopeBHMitchellPQCarleD. Developmental pathology and pedodontology. In: LobpriseHBDoddJR, eds. Wigg’s veterinary dentistry principles and practice. 2nd ed. Wiley Blackwell; 2019: 63‐79.
16.
D'AstousJ. An overview of dentigerous cysts in dogs and cats. Can Vet J. 2011;52(8):905‐907.
LiuBYuSFLiTJ. Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. J Oral Pathol Med. 2003;32(6):367‐375. doi:https://doi.org/10.1034/j.1600-0714.2003.00126.x
19.
JaffeHLLichtensteinL. Solitary unicameralbone bone cyst with emphasis on the roentgen picture, the pathologic appearance and the pathogenesis. Arch Surg. 1942;44:1004‐1025. doi:https://doi.org/10.1001/archsurg.1942.01210240043003
MascardEGomez-BrouchetALambotK. Bone cysts: unicameral and aneurysmal bone cyst. Orthop Traumatol Surg Res. 2015;101(1 Suppl):S119‐S127. doi:https://doi.org/10.1016/j.otsr.2014.06.031
22.
KoçNParlakŞ. Simple bone cyst of the hyoid: a radiological diagnosis and follow-up. Dent Med Probl. 2020;57(3):333‐337. doi:https://doi.org/10.17219/dmp/120079
23.
McCarthyEFrassicaF. Bone cysts. In: McCarthyEFrassicaF, eds. Pathology of bone and joint disorders: with clinical and radiographic correlation. 2nd ed. Cambridge University Press; 2014: 273‐285.
24.
SubramanianSKempAKViswanathanVK. Bone cyst. In: StatPearls[Internet].StatPearls Publishing; 2022. PMID: 30969671.
25.
McMullenPDBridgeJABlairEAYangCWCollinsJCiprianiNA. Aneurysmal bone cyst of the maxillary sinus with USP6 rearrangement: case report of a rare entity and review of the literature. Head Neck Pathol. 2019;13(3):281‐285. doi:https://doi.org/10.1007/s12105-018-0956-9
WarrenMXuDLiX. Gene fusions PAFAH1B1-USP6 and RUNX2-USP6 in aneurysmal bone cysts identified by next generation sequencing. Cancer Genet. 2017;212-213:13‐18. doi:https://doi.org/10.1016/j.cancergen.2017.03.007
28.
MankinHJHornicekFJOrtiz-CruzEVillafuerteJGebhardtMC. Aneurysmal bone cyst: a review of 150 patients. J Clin Oncol. 2005;23(27):6756‐6762. doi:https://doi.org/10.1200/JCO.2005.15.255
29.
HermannALPolivkaMLoitMPGuichardJPBoussonV. Aneurysmal bone cyst of the frontal bone—a radiologic–pathologic correlation. J Radiol Case Rep. 2018;12(7):16‐24. doi:https://doi.org/10.3941/jrcr.v12i7.3344
30.
MattBH. Aneurysmal bone cyst of the maxilla: case report and review of the literature. Int J Pediatr Otorhinolaryngol. 1993;25(1-3):217‐226. doi:https://doi.org/10.1016/0165-5876(93)90056-9
31.
MotamediMHNaviFEshkevariPS, et al.Variable presentations of aneurysmal bone cysts of the jaws: 51 cases treated during a 30-year period. J Oral Maxillofac Surg. 2008;66(10):2098‐2103. doi:https://doi.org/10.1016/j.joms.2008.05.364
32.
Kalantar MotamediMH. Aneurysmal bone cysts of the jaws: clinicopathological features, radiographic evaluation and treatment analysis of 17 cases. J Craniomaxillofac Surg. 1998;26(1):56‐62. doi:https://doi.org/10.1016/s1010-5182(98)80036-x
MotamediMHBehroozianAAziziTNazhvaniADMotaharyPLotfiA. Assessment of 120 maxillofacial aneurysmal bone cysts: a nationwide quest to understand this enigma. J Oral Maxillofac Surg. 2014;72(8):1523‐1530. doi:https://doi.org/10.1016/j.joms.2013.12.032
35.
SoukupJLewisJ. Oral and maxillofacial tumors, cysts, and tumor-like lesions. In: LobpriseHBDoddJR, eds. Wigg’s veterinary dentistry principles and practice. 2nd ed. Wiley Blackwell; 2019: 131‐154.
36.
DavidFLevingstoneTJSchneeweissW, et al.Enhanced bone healing using collagen-hydroxyapatite scaffold implantation in the treatment of a large multiloculated mandibular aneurysmal bone cyst in a thoroughbred filly. J Tissue Eng Regen Med. 2015;9(10):1193‐1199. doi:https://doi.org/10.1002/term.2006
BelknapEBBrodieSLowryJGetzelmanR. Aneurysmal bone cyst in a Holstein bull. J Am Vet Med Assoc. 1992;201(9):1413‐1415.
40.
SarierlerMCulluEYurekliYBirinciogluS. Bone cement treatment for aneurysmal bone cyst in a dog. J Vet Med Sci. 2004;66(9):1137‐1142. doi:https://doi.org/10.1292/jvms.66.1137
ShimadaAYanagidaMUmemuraTTsukamotoSSuganumaT. Aneurysmal bone cyst in a dog. J Vet Med Sci. 1996;58(10):1037‐1038. doi:https://doi.org/10.1292/jvms.58.10_1037
