Objective: This study examined the sociodemographic, health, and economic determinants of limitations in performing instrumental activities of daily living (IADL) in Canadians 65 years and older with emphasis on the role of relative body weight. Furthermore, the study examined the relationship between these limitations and the whole range of relative body weight while controlling for the above determinants. Method: This research used data collected in the Canadian Community Health Survey in 2005 on Canadians 65 years and older (N = 21,255). Results: The odds of experiencing IADL limitations were higher for women, the poor, and those not living with a partner. These odds also increased with advancing age and weaker physical health. Controlling for socioeconomic and health characteristics, the odds of experiencing such limitations were significantly elevated in underweight and obese individuals but not in overweight individuals. Discussion: Prevention and intervention strategies targeting underweight and obese individuals should be a policy priority.