Extracts of the testes of man and animal have been used for some time to enhance performance of a variety of sorts. Medical use of steroids dates back several decades, and recent intense athletic and fitness (bodybuilding) competition has driven some to use and abuse of testosterone and synthetic derivatives in the quest for that extra edge, despite a knowledge that anabolic steroids carry significant risk for liver, endocrine, and psychiatric toxicity, and also carry criminal penalties and disciplinary risks for athletes and health care workers who promote and traffic these substances outside their established medical uses.
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