Abstract
Many consultant pharmacists are familiar with the federal government's list of drug irregularities, or indicators, used as guidelines for performing drug regimen reviews; however, they are not always aware of the actual reasoning behind these indicators. The indicators are the minimal standards for drug regimen reviews and consultants must understand them thoroughly in order to advance further their clinical consultant practice. This article will address the clinical background for these indicators in order to enhance their use by consultants. Particular attention will be given to therapy modifications necessary in the older adult. Some specific topics covered include the monitoring of antipsychotic and antidepressant drugs, sedative/hypnotic therapy, cardiovascular drugs, certain antibiotics, laxatives, and drugs that require serum concentration monitoring.
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