Until recently, kinetic modeling of peritoneal dialysis (PD) was performed by engineers, scientists, or nephrologists at major teaching institutions. Now there are several “user-friendly” computer programs which permit the practicing nephrologist and dialysis staff to monitor adequacy of the individual PD patient and to optimize the dialysis prescription. In this brief article, the capabilities, methods, and data requirements of three programs are reviewed, and specific recommendations for the selection of a particular program are discussed.
KeshaviahP., EmersonP., VoneshE., BrandesJ.Relationship between body size, fill volume and mass transfer area coefficient in peritoneal dialysis.J Am Soc Nephrol1994; 4: 1820–6.
3.
FlessnerM.F.Peritoneal transport physiology: insights from basic research.J Am Soc Nephrol1991; 2: 122–35.
4.
DedrickR.L., FlessnerM.F., CollinsJ.M., SchultzJ.S.Is the peritoneum a membrane?ASAIO J1982; 5: 1–8.
GotchF., LippsB.J.PACK PD: A urea kinetic modeling computer program for peritoneal dialysis.Perit Dial Int1997; 17(Suppl 2): S126–30.
7.
TwardowskiZ.J.Clinical value of standardized equilibration tests in CAPD patients.Blood Purif1989; 7: 138–47.
8.
SmitheL., FoldenT., Young bloodB., PanlilioF., GotchF.Clinical evaluation of a peritoneal dialysis kinetic modeling set. In: KhannaR., ed. Advances in peritoneal dialysis.Toronto: Peritoneal Dialysis Publications, 1996; 12: 46–8.
9.
GotchF.A., LippsB.J., KeenM.L., PanlilioF., and coinvestigators for the Fresenius Randomized Dialysis Prescriptions and Clinical Outcome Study (RDP/ CO). Computerized urea kinetic modeling to prescribe and monitor delivered Kt/V (pKt/V, dKt/V) in peritoneal dialysis. In: KhannaR., ed. Advances in peritoneal dialysis.Toronto: Peritoneal Dialysis Publications, 1996; 12: 43–5.
10.
VoneshE.F., LysaghtM.J., MoranJ., FarrellP.Kinetic modeling as a prescription aid in peritoneal dialysis.Blood Purif1991; 9: 246–70.
11.
RippeB., HaraldssonB.Fluid and protein fluxes across small and large pores in the microvasculature. Application of two-pore equations.Acta Physiol Scand1987; 131: 411–28.
12.
RippeB., StelinG.Simulations of peritoneal solute transport during continuous ambulatory peritoneal dialysis (CAPD). Application of two-pore formalism.Kidney Int1989; 35: 1234–44.
13.
VoneshE.F., RippeB.Net fluid absorption under membrane transport models of peritoneal dialysis.Blood Purif1992; 10: 209–26.
14.
VoneshE.F., KeshaviahP.R.Applications in kinetic modeling using PD ADEQUEST.Perit Dial Int1997; 17(Suppl 2): Sl19–25.
15.
VoneshE.F., BurkartJ., McMurrayS.D., WilliamsP.F.Peritoneal dialysis kinetic modeling: validation in a multicenter clinical study.Perit Dial Int1996; 16: 471–81.
16.
HaraldssonB.Assessing the peritoneal dialysis capacity of individual patients.Kidney Int1995; 47: 1187–98.
