A 47-year-old man was treated by continuous ambulatory peritoneal dialysis (CAPD) because of chronic glomerulonephritis. One year later he developed skin friability and bullous dermatosis resembling porphyria cutanea tarda. The skin lesions were associated with an elevation of serum aminotransferases, most probably due to a blood transfusion-induced, non-A non-B hepatitis.
Urinary, fecal and blood porphyrins including the activity of red cell uroporphyrinogen decarboxylase were normal. Thus we accepted the diagnosis of pseudoporphyria cutanea tarda in view of the relatively frequent association of cutaneous disease with maintenance dialysis.
Poh-FitzpatrickM.B., BelletN., OeLeoV.A.Porphyria cutanea tarda in two patients treated with hemodialysis for chronic renal failure.NEJM1978; 299: 292–294.
6.
ParillaJ.G., OnegaR., PenaM.L.Porphyria cutanea tarda during maintenance hemodialysis.Br Med J1980; 280: 1358.
De VerneuilH., AitkenG., NordmannY.Familial and sporadic porphyria cutanea. Two different diseases.Hum Genet1978; 42: 145–151.
9.
OossM., Von TiepermannR., LookD.Hereditary and non-hereditary form of chronic hepatic porphyria: Different behaviour of uroporphyrinogen decarboxylase in liver and erythrocytes.Klin Wochenschr1980; 58: 1347–1356.
