What Happens to the Peritoneal Membrane in Long-Term Peritoneal Dialysis?

Slingeneyer A. , Canaud B. , Mion C. Permanent loss of ultrafiltration capacity of the peritoneum in long-term peritoneal dialysis: an epidemiological study. Nephron 1983; 33: 133–8.

Heimbürger O. , Waniewski J. , Werynski A. , Tranæus A. , Lindholm B. Peritoneal transport in CAPD patients with permanent loss of ultrafiltration capacity. Kidney Int 1990; 38: 495–506.

Ho-dac-Pannekeet M.M. , Atasever B. , Struijk D.G. , Krediet R.T. Analysis of ultrafiltration failure in peritoneal dialysis patients by means of standard peritoneal permeability analysis. Perit Dial Int 1997; 17: 144–50.

Smit W. , Struijk D.G. , Krediet R.T. The prevalence and causes of ultrafiltration failure in long-term CAPD (Abstract). Perit Dial Int 1999; 19(Suppl 1): S9.

Davies S.J. , Brown B. , Bryan J. , Russell G.I. Clinical evaluation of the peritoneal equilibration test: a population-based study. Nephrol Dial Transplant 1993; 8: 64–70.

Rippe B. How to measure ultrafiltration failure: 2.27% or 3.86% glucose? Perit Dial Int 1997; 17: 125–8.

Selgas R. , Munoz J. , Cigarran S. , Ramos P. , L–Revuelta K. , Escuin F. Peritoneal functional parameters after five years on continuous ambulatory peritoneal dialysis (CAPD): the effect of late peritonitis. Perit Dial Int 1989; 9: 329–32.

Pollock C.A. , Ibels L.S. , Hallett M.D. , Cocksedge B. , Caterson R.J. , Mahony J.F. Loss of ultrafiltration in continuous ambulatory peritoneal dialysis (CAPD). Perit Dial Int 1989; 9: 107–10.

Park M.S. , Lee J. , Lee M.S. , Baick S.H. , Hwang S.D. , Lee H.B. Peritoneal solute clearances after four years of continuous ambulatory peritoneal dialysis (CAPD). Perit Dial Int 1989; 9: 75–8.

Lameire N.H. , Vanholder R. , Veyt D. , Lambert M.C. , Ringoir S. A longitudinal, five year survey of urea kinetic parameters in CAPD patients. Kidney Int 1992; 42: 426–32.

Faller B. , Lameire N. Evolution of clinical parameters and peritoneal function in a cohort of CAPD patients followed over 7 years. Nephrol Dial Transplant 1994; 9: 280–6.

Gilmour J. , Wu G. , Khanna R. , Schilling H. , Mitwalli A. , Oreopoulos D.G. Long-term continuous ambulatory peritoneal dialysis. Perit Dial Bull 1985; 5: 112–18.

Struijk D.G. , Krediet R.T. , Koomen G.C. , Boeschoten E.W. , Hoek F.J. , Arisz L. A prospective study of peritoneal transport in CAPD patients. Kidney Int 1994; 45: 1739–44.

Selgas R. , Fernandez–Reyes M.J. , Bosque E. , Bajo M.A. , Borrego F. , Jimenez C. Functional longevity of the human peritoneum: how long is continuous peritoneal dialysis possible? Results of a prospective medium long-term study. Am J Kidney Dis 1994; 23: 64–73.

Davies S.J. , Bryan J. , Phillips L. , Russell G.I. Longitudinal changes in peritoneal kinetics: the effects of peritoneal dialysis and peritonitis. Nephrol Dial Transplant 1996; 11: 498–506.

Struijk D.G. , Krediet R.T. , Koomen G.C. , Hoek F.J. , Boeschoten E W. , vd Reijden H.J. Functional characteristics of the peritoneal membrane in long-term continuous ambulatory peritoneal dialysis. Nephron 1991; 59: 213–20.

von Lilien T. , Salusky I.B. , Little R.J. , Alliapolous J.C. , Leichter H.E. , Hall T.L. Peritoneal kinetics in children undergoing continuous ambulatory/cycling peritoneal dialysis. Am J Kidney Dis 1987; 10: 431–8.

Procaccini D.A. , Querques M. , Tappi A. , Strippoli P. Peritoneal clearances. Long-term study. ASAIO Trans 1988; 34: 437–40.

Lo W.K. , Brendolan A. , Prowant B.F. , Moore H.L. , Khanna R. , Twardowski Z.J. Changes in the peritoneal equilibration test in selected chronic peritoneal dialysis patients. J Am Soc Nephrol 1994; 4: 1466–74.

Ota K. , Mineshima M. , Watanabe N. , Naganuma S. Functional deterioration of the peritoneum: does it occur in the absence of peritonitis? Nephrol Dial Transplant 1987; 2: 30–3.

Blake P.G. , Abraham G. , Sombolos K. , Izatt S. , Weissgarten J. , Ayiomamitis A. Changes in peritoneal membrane transport rates in patients on long term CAPD. Adv Perit Dial 1989; 5: 3–7.

Monquil M.C. , Imholz A.L. , Struijk D.G. , Krediet R.T. Does impaired transcellular water transport contribute to net ultrafiltration failure during CAPD? Perit Dial Int 1995; 15: 42–8.

Chan P.C. , Chan C.Y. , Wu P.G. , Cheng I.K. , Chan M.K. Long-term peritoneal clearances in patients on continuous ambulatory peritoneal dialysis. Int J Artif Organs 1990; 13: 707–8.

Nakayama M. , Kawaguchi Y. , Yamada K. , Hasegawa T. , Takazoe K. , Katoh N. Immunohistochemical detection of advanced glycosylation end-products in the peritoneum and its possible pathophysiological role in CAPD. Kidney Int 1997; 51: 182–6.

Krediet R.T. , Zemel D. , Imholz A.L. , Struijk D.G. Impact of surface area and permeability on solute clearances. Perit Dial Int 1994; 14(Suppl 3): S70–7.

Pollock C.A. , Ibels L.S. , Caterson R.J. , Mahony J F. , Waugh D.A. , Cocksedge B. Continuous ambulatory peritoneal dialysis. Eight years of experience at a single center. Medicine (Baltimore) 1989; 68: 293–308.

Maiorca R. , Vonesh E F. , Cavalli P. , De Vecchi A. , Giangrande A. , La Greca G. A multicenter, selection-adjusted comparison of patient and technique survivals on CAPD and hemodialysis. Perit Dial Int 1991; 11: 118–27.

Lupo A. , Tarchini R. , Carcarini G. , Catizone L. , Cocchi R. , De Vecchi A. Long-term outcome in continuous ambulatory peritoneal dialysis: a 10-year-survey by the Italian Cooperative Peritoneal Dialysis Study Group. Am J Kidney Dis 1994; 24: 826–37.

Kawaguchi Y. , Hasegawa T. , Nakayama M. , Kubo H. , Shigematsu T. Issues affecting the longevity of the continuous peritoneal dialysis therapy. Kidney Int 1997; 52(Suppl 62): S105–7.

Davies S.J. , Phillips L. , Griffiths A.M. , Russell L.H. , Naish P F. , Russell G.I. What really happens to people on long-term peritoneal dialysis? Kidney Int 1998; 54: 2207–17.

Maiorca R. , Vonesh E. , Cancarini G.C. , Cantaluppi A. , Manili L. , Brunori G. A six-year comparison of patient and technique survivals in CAPD and HD. Kidney Int 1988; 34: 518–24.

Gokal R. , Jakubowski C. , King J. , Hunt L. , Bogle S. , Baillod R. Outcome in patients on continuous ambulatory peritoneal dialysis and haemodialysis: 4-year analysis of a prospective multicentre study. Lancet 1987; 14: 1105–9.

Maiorca R. , Cancarini G.C. , Zubani R. , Camerini C. , Manili L. , Brunori G. CAPD viability: a long-term comparison with hemodialysis. Perit Dial Int 1996; 16: 276–87.

Wu C.H. , Huang C.C. , Huang J.Y. , Wu M.S. , Leu M.L. High flux peritoneal membrane is a risk factor in survival of CAPD treatment. Adv Perit Dial 1996; 12: 105–9.

Wang T. , Heimbürger O. , Waniewski J. , Bergström J. , Lindholm B. Increased peritoneal permeability is associated with decreased fluid and small-solute removal and higher mortality in CAPD patients. Nephrol Dial Transplant 1998; 13: 1242–9.

Churchill D.N. , Thorpe K.E. , Nolph K.D.A. , Keshaviah P.R. , Oreopoulos D.G. , Pagé D. Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. J Am Soc Nephrol 1998; 9: 1285–92.

Davies S.J. , Phillips L. , Russell G.I. Peritoneal solute transport predicts survival on CAPD independently of residual renal function. Nephrol Dial Transplant 1998; 13: 962–8.

Rubin J. , Herrera G.A. , Collins D. An autopsy study of the peritoneal cavity from patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 1991; 18: 97–102.

Flessner M.F. . Osmotic barrier of the parietal peritoneum. Am J Physiol 1994; 267: F861–70.

Gotloib L. , Bar–Sella P. , Shostak A. Reduplicated basal lamina of small venules and mesothelium of human parietal peritoneum: ultrastructural changes of reduplicated peritoneal basement membrane. Perit Dial Bull 1985; 5: 212–15.

Di Paolo N. , Sacchi G. Anatomy and physiology of the peritoneal membrane. Contrib Nephrol 1990; 84: 10–26.

Dobbie J.W. Monitoring peritoneal histopathology in peritoneal dialysis: the role of a biopsy registry. Dial Transplant 1989; 18: 319–25.

Dobbie J.W. , Lloyd J.K. , Gall C.A. Categorization of ultra-structural changes in peritoneal mesothelium, stroma and blood vessels in uremia and CAPD patients. Adv Perit Dial 1990; 6: 3–12.

Dobbie J.W. The peritoneal biopsy registry: a watchdog for peritoneal dialysis. Semin Dial 1992; 5: 20–3.

Mateijsen M.A. , van der Wal A.C. , Hendriks P.M. , Zweers M.M. , Mulder J. , Struijk D.G. Vascular and interstitial changes in the peritoneum of CAPD patients with peritoneal sclerosis. Perit Dial Int 1999; 19: 517–25.

Honda K. , Nitta K. , Horita S. , Yumura W. , Nihei H. Morphological changes in the peritoneal vasculature of patients on CAPD with ultrafiltration failure. Nephron 1996; 72: 171–6.

Williams J.D. , Craig K.J. , Topley N. , Von Ruhland C. , Newman G.R. , Williams G.T. Submesothelial fibrosis in the peritoneal membrane of patients on peritoneal dialysis correlates with the presence of vasculopathy (Abstract). J Am Soc Nephrol 2000; 11: 314A.

Verger C. , Brunschvicg O. , Le Charpentier Y. , Lavergne A. , Vantelon J. Structural and ultrastructural peritoneal membrane changes and permeability alterations during continuous ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc 1981; 18: 199–205.

Combet S. , Miyata T. , Moulin P. , Pouthier D. , Goffin E. , Devuyst O. Vascular proliferation and enhanced expression of endothelial nitric oxide synthase in human peritoneum exposed to long-term peritoneal dialysis. J Am Soc Nephrol 2000; 11: 717–28.

Krediet R.T. , Zweers M.M. , van der Wal A.C. , Struijk D.G. Neoangiogenesis in the peritoneal membrane. Perit Dial Int 2000; 20(Suppl 2): S19–25.

Sharma K. , Ziyadeh F.N. Hyperglycemia and diabetic kidney disease. the case for transforming growth factor-beta as a key mediator. Diabetes 1995; 44: 1139–46.

De Vriese A.S. , Tilton R.G. , Stephan C.C. , Elger M. , Kriz W. , Lameire N. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol 2001; 12: 993–1000.

Blobe G.C. , Schiemann W P. , Lodish H F. Role of transforming growth factor beta in human disease. N Engl J Med 2000; 342: 1350–8.

Neufeld G. , Cohen T. , Gengrinovitch S. , Poltorak Z. Vascular endothelial growth factor and its receptors. FASEB J 1999; 13: 9–22.

Kang D.H. , Hong Y.S. , Lim H.J. , Choi J.H. , Han D.S. , Yoon K.I. High glucose solution and spent dialysate stimulate the synthesis of transforming growth factor-beta1 of human peritoneal mesothelial cells: effect of cytokine costimulation. Perit Dial Int 1999; 19: 221–30.

Selgas R. , del Peso G. , Bajo M.A. , Castro M.A. , Molina S. , Cirugeda A. Spontaneous VEGF production by cultured peritoneal mesothelial cells from patients on peritoneal dialysis. Perit Dial Int 2000; 20: 798–801.

McLaren J. , Prentice A. , Charnock–Jones D.S. , Millican S.A. , Muller K.H. , Sharkey A.M. Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids. J Clin Invest 1996; 98: 482–9.

Zweers M.M. , de Waart D.R. , Smit W. , Struijk D.G. , Krediet R.T. Growth factors VEGF and TGF-beta1 in peritoneal dialysis. J Lab Clin Med 1999; 134: 124–132.

Zweers M.M. , Struijk D.G. , Smit W. , Krediet R.T. Vascular endothelial growth factor in peritoneal dialysis: a longitudinal follow-up. J Lab Clin Med 2001; 137: 125–32.

De Vriese A.S. , Tilton R.G. , Stephan C.C. , Lameire N. Diabetes-induced microvascular proliferation and hyperpermeability in the peritoneum: role of vascular endothelial growth factor. J Am Soc Nephrol 2001; 12: 1734–41.

Inagi R. , Miyata T. , Yamamoto T. , Suzuki D. , Urakami K. , Saito A. Glucose degradation product methylglyoxal enhances the production of vascular endothelial growth factor in peritoneal cells: role in the functional and morphological alterations of peritoneal membranes in peritoneal dialysis. FEBS Lett 1999; 463: 260–4.

Henderson I.S. , Couper L.A. , Lumsden A. The effect of shelf-life of peritoneal dialysis fluid on ultrafiltration in CAPD. In: La Greca G. , Chiaramonte S. , Fabris A. , Feriani M. , Ronco C. , eds. Peritoneal Dialysis. Proceedings of the 2nd International Course. Milan: Wichtig Editore; 1986: 85–6.

Miyata T. , van Ypersele de Strihou C. , Kurokawa K. , Baynes J.W. Alterations in nonenzymatic biochemistry in uremia: origin and significance of “carbonyl stress” in long-term uremic complications. Kidney Int 1999; 55: 389–99.

Baynes J.W. , Thorpe S.R. Role of oxidative stress in diabetic complications. A new perspective on an old paradigm. Diabetes 1999; 48: 1–9.

Dawnay A.B. , Millar D.J. Glycation and advanced glycation end-product formation with icodextrin and dextrose. Perit Dial Int 1997; 17: 52–8.

Friedlander M.A. , Wu Y.C. , Schulak J.A. , Monnier V.M. , Hricik D.E. Influence of dialysis modality on plasma and tissue concentrations of pentosidine in patients with end-stage renal disease. Am J Kidney Dis 1995; 25: 445–51.

Friedlander M.A. , Wu Y.C. , Elgawish A. , Monnier V.M. Early and advanced glycosylation end products. Kinetics of formation and clearance in peritoneal dialysis. J Clin Invest 1996; 97: 728–35.

Linden T. , Forsbäck G. , Deppisch R. , Henle T. , Wieslander A. 3-Deoxyglucosone, a promoter of advanced glycation end products in fluids for peritoneal dialysis. Perit Dial Int 1998; 18: 290–3.

Schalkwijk C.G. , Posthuma N. , ten Brink H.J. , ter Wee P.M. , Teerlink T. Induction of 1,2-dicarbonyl compounds, intermediates in the formation of advanced glycation end-products, during heat-sterilization of glucose-based peritoneal dialysis fluids. Perit Dial Int 1999; 19: 325–33.

Lamb E. , Cattell W.R. , Dawnay A. Glycated albumin in serum and dialysate of patients on continuous ambulatory peritoneal dialysis. Clin Sci (Lond) 1993; 84: 619–26.

Lamb E.J. , Cattell W.R. , Dawnay A.B. In vitro formation of advanced glycation end products in peritoneal dialysis fluid. Kidney Int 1995; 47: 1768–74.

Yamada K. , Miyahara Y. , Hamaguchi K. , Nakayama M. , Nakano H. , Nozaki O. Immunohistochemical study of human advanced glycosylation end-products (AGE) in chronic renal failure. Clin Nephrol 1994; 42: 354–61.

Honda K. , Nitta K. , Horita S. , Yumura W. , Nihei H. , Nagai R. Accumulation of advanced glycation end products in the peritoneal vasculature of continuous ambulatory peritoneal dialysis patients with low ultra-filtration. Nephrol Dial Transplant 1999; 14: 1541–9.

Park M.S. , Lee H.A. , Chu W.S. , Yang D.H. , Hwang S.D. Peritoneal accumulation of AGE and peritoneal membrane permeability. Perit Dial Int 2000; 20: 452–60.

Schmidt A.M. , Yan S.D. , Wautier J.L. , Stern D. Activation of receptor for advanced glycation end products. A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 1999; 84: 489–97.

Lu M. , Kuroki M. , Amano S. , Tolentino M. , Keough K. , Kim I. Advanced glycation end products increase retinal vascular endothelial growth factor expression. J Clin Invest 1998; 101: 1219–24.

Hirata C. , Nakano K. , Nakamura N. , Kitagawa Y. , Shigeta H. , Hasegawa G. Advanced glycation end products induce expression of vascular endothelial growth factor by retinal Muller cells. Biochem Biophys Res Commun 1997; 236: 712–15.

Murata T. , Nagai R. , Ishibashi T. , Inomuta H. , Ikeda K. , Horiuchi S. The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas. Diabetologia 1997; 40: 764–9.

Yamagishi S. , Yonekura H. , Yamamoto Y. , Katsuno K. , Sato F. , Mita I. Advanced glycation end products– driven angiogenesis in vitro. Induction of the growth and tube formation of human microvascular endothelial cells through autocrine vascular endothelial growth factor. J Biol Chem 1997; 272: 8723–30.

Gokal R. Newer peritoneal dialysis solutions. Adv Ren Replace Ther 2000; 7: 302–9.

Barré D.E. , Chen C. , Cooker L. , Moberly J.B. Decreased in vitro formation of AGEs with Extraneal solution compared to dextrose-containing peritoneal dialysis solutions. Adv Perit Dial 1999; 15: 12–16.

Lee J.H. , Reddy D.K. , Saran R. , Moore H.L. , Twardowski Z.J. , Nolph K.D.A. Advanced glycosylation end-products in diabetic rats on peritoneal dialysis using various solutions. Perit Dial Int 2000; 20: 643–51.

Posthuma N. , Verbrugh H.A. , Donker A.J. , van Dorp W. , Dekker H.A. , Peers E.M. Peritoneal kinetics and mesothelial markers in CCPD using icodextrin for daytime dwell for two years. Perit Dial Int 2000; 20: 174–80.

Millar D.J. , Holmes C. , Faict D. , Dawnay A. Comparison of in vitro AGE formation between standard PD fluid and a novel bicarbonate/lactate formulation. Adv Perit Dial 1998; 14: 191–4.

Park M.S. , Kim J.K. , Holmes C. , Weiss M F. Effects of bicarbonate/lactate solution on peritoneal advanced glycosylation end-product accumulation. Perit Dial Int 2000; 20(Suppl 5): S33–8.

Jonasson P. , Braide M. A commercially available PD fluid with high pH and low GDP induces different morphological changes of rat peritoneum in intermittent PD. Adv Perit Dial 1998; 14: 48–53.