Restricted accessResearch articleFirst published online 2000-11
Reduced 1,2-Dicarbonyl Compounds in Bicarbonate/Lactate-Buffered Peritoneal Dialysis (PD) Fluids and PD Fluids Based on Glucose Polymers or Amino Acids
WieslanderA.P., NordinM.K., MartinsonE., KjellstrandP.T., BobergU.C.Heat sterilized PD fluids impair growth and inflammatory responses of cultured cell lines and human leukocytes.Clin Nephrol1993; 39: 343–8.
2.
JonassonP., BaggeU., WieslanderA., BraideM.Heatsterilized PD fluid blocks leukocyte adhesion and increases flow velocity in rat peritoneal venules.Perit Dial Int1996; 16(Suppl 1): S137–40.
3.
Nilsson–ThorellC.B., MuscaluN., AndrenA.H.G., KjellstrandP.T.T., WieslanderA.P.Heat sterilization of fluids for peritoneal dialysis gives rise to aldehydes.Perit Dial Int1993; 13: 208–13.
4.
KjellstrandP., MartinsonE., WieslanderA., HolmquistB.Development of toxic degradation products during heat sterilization of glucose-containing fluids for peritoneal dialysis: Influence of time and temperature.Perit Dial Int1995; 15: 26–32.
5.
LeggeM., LashG.E., BirdS.D., WalkerR.J.Formaldehyde in heat sterilized peritoneal dialysis solutions: Scavenging system for its removal.Perit Dial Int1998; 18: 228–31.
6.
WieslanderA.P.Cytotoxicity of peritoneal dialysis fluid — is it related to glucose breakdown products?Nephrol Dial Transplant1996; 11: 958–9.
7.
WieslanderA., ForsbackG., SvenssonE., LindenT.Cytotoxicity, pH, and glucose degradation products in four different brands of PD fluid.Adv Perit Dial1996; 12: 57–60.
8.
LindenT., ForsbäckG., DeppischR., HenleT., WieslanderA.3-Deoxyglucosone, a promoter of advanced glycation end products in fluids for peritoneal dialysis.Perit Dial Int1998; 18: 290–3.
9.
SchalkwijkC.G., PosthumaN., ten BrinkH.J., ter WeeP.M., TeerlinkT.Induction of 1,2-dicarbonyl compounds, intermediates in the formation of advanced glycation end-products, during heat-sterilization of glucose-based peritoneal dialysis fluids.Perit Dial Int1999; 19: 325–33.
10.
OkadoA., KawasakiY., HasuikeY., TakahashiM., TeshimaT., FujiiJ.Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines.Biochem Biophys Res Commun1996; 225: 219–24.
11.
KangY., EdwardsL.G., ThornalleyP.J.Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA, G1, growth arrest and induction of apoptosis.Leukemia Res1996; 20: 397–405.
12.
ThornalleyP.J., LangborgA., MinhasH.Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.Biochem J1999; 344: 109–16.
13.
LambE.J., CattellW.R., DawnayA.B.In vitro formation of advanced glycation end products in peritoneal dialysis fluid.Kidney Int1995; 47: 1768–74.
14.
NakayamaM., KawaguchiY., YamadaK., HasegawaT., TakazoeK., KatohN.Immunohistochemical detection of advanced glycosylation endproducts in the peritoneum and its possible pathophysiological role in CAPD.Kidney Int1997; 51: 182–6.
15.
InagiR., MiyataT., YamamotoT., SuzukiD., UrakamiK., SaitoA.Glucose degradation product methyl-glyoxal enhances the production of vascular endothelial growth factor in peritoneal cells: Role in the functional and morphological alterations of peritoneal membranes in peritoneal dialysis.FEBS Lett1999; 17: 260–4.
16.
WieslanderA.P., DeppischR., SvenssonE., ForsbackG., SpeidelR., RippeB.In vitro biocompatibility of a heat-sterilized, low-toxic, and less acidic fluid for peritoneal dialysis.Perit Dial Int1995; 15: 158–64.
17.
CookerL.A., LuneburgP., FaictD., ChooC., HolmesC.J.Reduced glucose degradation products in bicarbonate/ lactate-buffered peritoneal dialysis solutions produced in two-chambered bags.Perit Dial Int1997; 17: 373–8.
18.
SundaramS., CendorogloM., CookerL.A., JaberB., FaictD., HolmesC.J.Effect of two-chambered bicarbonate lactate-buffered peritoneal dialysis fluids on peripheral blood mononuclear cell and polymorphonuclear cell function in vitro.Am J Kidney Dis1997; 30: 680–9.
19.
CookerL.A., ChooC.G., LuneburgP., PamelaJ., HolmesC.J.Effect of icodextrin peritoneal dialysis solution on cell proliferation in vitro.Adv Perit Dial1999; 15: 17–20.
20.
DawnayA.B., MillarD.J.Glycation and advanced glycation end-product formation with icodextrin and dextrose.Perit Dial Int1997; 17: 52–8.
21.
MillarD.J., HolmesC., FaictD., DawnayA.Comparison of in vitro AGE formation between standard PD fluid and a novel bicarbonate/lactate formulation.Adv Perit Dial1998; 14: 191–4.
