How do Tetracyclines Work?

Abstract

This paper is a summary of a panel discussion by the following panelists: L. Golub, J. te Koppele, G. Nieman, M. Nelson, R. Ashley, T. Sorsa, and S. Simon. The panel discussed the mechanisms by which the tetracyclines and their non-antimicrobial counterparts may provide therapeutic efficacy in a variety of chronic and acute diseases.

Keywords

Tetracyclines matrix metalloproteinases reactive oxygen species selective cytotoxicity osteoclasts acute respiratory distress syndrome serine proteinases.

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