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Abstract

Magnetic resonance imaging has been widely used for medical diagnosis in recent years. The knowledge of the proton spin-lattice relaxation time, T₁, represents the basis for NMR imaging. In the present study, we measured T₁ in saliva, gingival fluid, gingival blood, and inflamed gingiva by means of a pulsed NMR Fourier-transform spectrometer. From several measurements, we found the following average T₁ values: in saliva, T₁ = 2550 msec; in gingival fluid, T₁ = 2085 msec; in gingival blood, T₁ = 1515 msec; and in inflamed gingiva samples, T₁ = 840 msec.

In addition, electron paramagnetic resonance imaging was used to demonstrate the in vitro diffusion processes of spin-labeled molecules into tooth enamel by application of the linear magnetic field gradient to a conventional EPR spectrometer. The diffusion coefficient for the nitroxide spin-labeled molecules into tooth enamel was evaluated as D = 10^-7 cm² sec^-1.

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NMR Imaging in Dentistry: Relaxation and Diffusion Studies

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