The relationships between craniofacial and other medical pathologies are not always obvious but may be very significant as they influence the extent of disease, accuracy of differential diagnoses, treatment schedules, and appropriateness and utilization of health-care resources. Among the relationships dis cussed are periodontal and endodontic infections, bacteremias and antibiotics, iatrogenics, viral and fungal infections, oncological interactions, temporo mandibular joint disease, dental implants, antide pressant therapy, psychiatric and neurological influ ences, and dental restorations.
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