The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of biocompatibility—the responses evoked by the material as well as the methods for their detection. The paper also mentions a few methods of improvement of material compatibility.
1. Williams, D. F.1987. Progress in Biomedical Engg., D. E. Williams, ed., Elsevier, Amsterdam, pp. 1-72.
2.
2. Offeman, R. D. and M. C. Williams. 1976. "Shear Induced Hemolysis; Effects of Blood Chemistry and Shear Surface,"Biomaterial Medical Devices Artificial Organs, 4:49-55.
3.
3. Bhowmick, U. N., R. R. Puniyani and S. Basu. 1989. "Biocompatibility Evaluation of Synthetic Materials Based on Changes in Hemorheological Parameters in Blood,"CGCRI Bulletin, 36:50-55.
4.
4. Hanson, S. R., L. A. Harker, D. D. Ratner and A. S. Hoffman. 1980. "In vivo Evaluation of Artificial Surfaces with an Non-Human Primate Model of Arterial Thrombosis,"J. Lab. Clin. Med., 95:289-295.
5.
5. Horng, B. L., R. W. Hergenrother, J. H. Silver, R. Jui-che Lin, T. W. Brodhagen and S. L. Cooper. 1994. "Ex vivo Blood Compatibility of Silicone Containing Biomaterials,"J. Materials Science: Materials in Medicine, 5:207-213.
6.
6. Cazenave, J. PiJ. N. Mulvihill, J. G. Husman and W. G. A. Van Aken. 1985. "The Use of Monoclonal Antibodies Against Platelet Membranes, Glycoproteins to Measure Platelet Accumulation on Artificial Surfaces,"Proc. of Rhone Poulenc Sante, Inserm Conf. at Menthan Saint Bernard, France.
7.
7. Courtney, J. M., M. Travers, S. K. Bowry, C. R. M. Prentice, D. D. O. Lowe and C. D. Forbes. 1987. "Measurement of Platelet Loss in the Blood Assessment of Biomaterials,"Biomaterials, 8:231-236.
8.
8. Larsson, R., L. E. Linder, I. Cuurelaru, B. Buscimi, R. Sherman and E. Eriksson. 1990. "Initial Platelet Adhesion and Platelet Shape on Polymer Surfaces with Different Carbon Bonding Characteristics (as in vitro Study of Teflon, Pellethane and XLON Intravenous Cannulae),"J. of Material Science: Materials in Medicine, 1:157-162.
9.
9. Ikada, Y. 1986. "Development of a Polymer Surface with Non Adherent Platelet Properties,"Proc. 5th Int. Confi Polymers in Medicine and Surgery, Plastic and Rubber Inst., London 611.
10.
10. Schultz, J. S., J. D. Goddard, A. Ciankowski, J. A. Penner and S. M. Lindeneauerr. 1977. "An ex-vivo Method for the Evaluation of Biomaterials in Contact with Blood,"Ann. N.Y Acad. Scie., 283:494-499.
11.
11. Borovetz, H. S., A. D. Haubold, D. M. Herculus and R. L. Hardesty. 1979. "Development of an All Carbon Membrane Oxygenator," Abstract, 14th Biannual Conference of Carbon, American Carbon Society, Univ. of Park, p. 56.
12.
12. Whalen, R. L., D. L. Jeffrey and J. C. Normann. 1973. "A New Method of in vivo Screening of Thromboresistance Biomaterial, Utilizing Flow Measurements,"Trans. Amer. Soc. Art. Int. Organ, 24:19-23.
13.
13. Boretos, J. W. and W. S. Piearce. 1968. "Segmented Polyurethanes, a Poly-ether Polymer; An Initial Evaluation for Biomedical Applications,"J. Biomed. Mat. Res., 2:121-126.
14.
14. Lindhout, T., R. Blezer, C. Maassen, V. Heijnen and C. P. M. Reuteingsperger. 1995. "Platelet Procoagulant Surface as an Essential Parameter for the in vitro Evaluation of the Blood Compatibility of Polymers,"J. of Materials Science: Materials in Medicine, 6:367-372.
15.
15. Dintenfass, L.1966. "Viscometry of Human Blood for Shear Rates of 0-100,000 sec/l,"Nature, London, pp. 211, 632.
16.
16. Dintenfass, L. and J. H. Stewart. 1971. "Formation, Viscosity and Degradation of Artificial Thrombi after Cadaveric Donor Kidney Transplantations,"Throm. Diath. Hemorh., 76:24.
17.
17. Wagner, M., G. Ruul, J. Teresi and K. Kayser. 1968. "The Use of Spandex as a Vascular Patch Graft Material,"Surg. Gync. Obst., pp. 127, 805.
18.
18. Hayden, W. H., W. G. Moffatt and J. Wulff. 1965. The Structural Properties of Materials, New York: Wiley, 3:13.
19.
19. Kinney, G. E 1957. Engineering Properties and Applications of Plastics. New York: Wiley, p. 111.
20.
20. Park, J. B.1984. Biomaterials Science & Engineering. New York: Plenum Press, p. 238.
21.
21. Nanas, J. N.1988. "Biocompatibility Overview-Classes of Materials, Inflammation, Infection,"Encyclopedia of Medical Devices and Instrumentation, J. G. Webster, ed., Wiley Interscience Publications, 1:181-195.
22.
22. Baier, R. E., V. L. Gott and A. Ferusca. 1975. "Surface Chemical Evaluation of Thromboresistance Material Before and After Venous Implantation,"Trans. Amer. Soci. Art. Int. Organ, 21:49-55.
23.
23. Barbucci, R., A. Albanese, F. Tempesti, A. Baszkin, R. Eloy, N. Weill, E. Martuscelli and S. Cimmino. 1994. "Study of Hemodialysis Materials; Physico-Chemical and Biological Characterization of EVALVA, EVAPA and Heparinized EVAPA,"J. of Materials Science; Materials in Medicine, 5:844-849.
24.
24. Thompson, N. G., R. A. Buchanan and J. E. Lemons. 1979. "In vitro Corrosion of Ti6AlV and type 316 L Stainless Steel When Galvanically Coupled with Carbon,"J. Biomen. Mat. Res., 13:35-40.
25.
25. Park, J. B.1984. Biomaterials Science and Engineering, New York: Plenum Press, p. 218.
26.
26. Ciapetti, G., D. Ciranchi, S. Stea, E. Cenni, M. E. Donati, A. Pizzoferrato, P. Schiavon and R. Giuliani. 1994. "In vitro Assessment of Lymphocytes Response Following Re-Exposure to Silicone,"J. of Materials Science: Materials in Medicine, 5:640-643.
27.
27. Yoshikawa, S., H. Fukumura, Y. Akagaki and S. Y. Inai. 1988. Implant Materials in Biofunction, Amsterdam: Elsevier Science, p. 187.
28.
28. Berger, M., B. Broxup and M. V. Sefton. 1994. "Using Elisa to Evaluate Complement Activation by Reference Materials,"J. of Materials Science: Materials in Medicine, 5:622-627.
29.
29. Ikeda, Y., S. Kohijiya, S. Yamashita and H. Fukumura. 1991. "Activation of Complement in Human Serum by Polyurethene Having PEO-PTMO-PEO as Soft Segment,"J. Mat. Science: Materials in Medicine, 2:110-117.
30.
30. Chiu, T. H., E. Nyilas and L. R. Turcotte. 1978. "Microcalorimetric and Electrophoretic Studies of Protein Sorption from Plasma,"Trans. Am. Soc. Artif Inter. Organs, 24:389-393.
31.
31. Chiu, T. H., E. Nyilas and D. M. Lederman. 1976. "Thermodynamics of Native Protein/Foreign Surface Interactions IV Calorimetric and Microelectrophoretic Study of Human Fibrinogen Sorption onto Glass and LTI Carbon,"Trans. Am. Soc. Artif. Intern. Organs, 22:498-502.
32.
32. Warkentin, P. H., I. Lundstrom and P. Tengvall. 1993. "Direct Immunodetection of Surface Adsorbed Proteins,"J. Mater. Science: Materials in Medicine, 4:318-326.
33.
33. Lyman, B. J., K. Knutzen, B. McNeill and K. Shibatani. 1975. "The Effects of Chemical Structure and Surface Properties on the Coagulation of Blood,"Trans. Am. Soci. Art. Int. Organs, 21:49-54.
34.
34. Lowe, G. D. O., M. M. Reavey, R. V. Johnson, C. D. Forbes and C. R. M. Prentice. 1976. "Increase Platelet Aggregates in Vascular and Non Vascular Illness-Correlation with Plasma Fibrinogen and Effect of Ancrod,"Thromb. Res., 14:337-341.
35.
35. Tengvall, P., I. Lundstrom, C. Freiji, M. Larsson, M. Kober and B. Wesslen. 1993. "Ellipsometric Studies of Antisera Binding onto Medical Polyurethanes Immersed in Human Plasma in vitro,"J. of Material Science: Materials in Medicine, 4:305-310.
36.
36. Puniyani, R. R., R. S. Ajmani, R. V. Gupte and D. Doshi. 1995. "Hemocompatibility of Biomaterials,"Trends in Biomaterials and Organs, 9:19-21.
37.
37. Venkidachalam, G., U. N. Bhowmick, D. Datta and S. Basu. 1990. "Hemocompatibility Evaluation of Synthetic Biomaterials for Use in Extracorporeal Devices,"Trends in Biomat. and Art. Organs, 5:31-38.
38.
38. Mutlu, M., T. M. Erean and E. Pisku. 1989. "Blood Plasma Proteins Blood Cells on Polyurethane and Alkylsiloxane Plasma Stimulus Response Technique. Part I-Adsorption Data,"Clinical Materials, 4:61-76.
39.
39. Singhal, J. R., J. Singh, A. Ray and H. Singh. 1989. "Polyamidoamines Containing Nylon Six Blocks as Antithrombogenic Materials,"Third National Conference on Biomaterials and Artificial Organs.
40.
40. Nojiri, C., S. Kuroda, K. Hagiwara, K. D. Park, K. Senshu, T. Kido, K. Sakar and T. Akutsu. 1995. "In vitro Studies of Heparin Immobilised and Sulfonated Polyurethane Using Epifluorescent Video Microscopy,"41st Annual ASAIO Conf ASAIO, 41:3.
41.
41. Vulic, I., T. Okani, F. J. Van der Gaag, S. W. Kim and J. Feijen. 1993. "Heparin Containing Block Co-Polymers,"J. of Material Science: Materials in Medicine, 4:448-459.
42.
42. Parzer, S., P. Balcke and C. Mannhalter. 1993. "Adsorption of Coagulation Factors onto Hemodialysis Membranes During Standard Hemodialysis,"J. of Materials Science: Materials in Medicine, 4:12-16.
43.
43. Sly, M. K., M. D. Prazer and R. C. Eberhart. 1995. "Inhibition of Surface Induced Platelet Activation by Nitric Oxide,"41st Annual ASAIO Conf. ASAIO, 41:3.
44.
44. Kishida, A., Y. Akatsuka, Y. Veno, M. Yanagi and T. Aiko. 1995. "In vitro and ex-vivo Evaluation of Anti-Thrombogenecity of Human Thrombomodulin Immobilized Biomaterials,"41st Annual ASA1O, Conf ASAIO, 41:3.
45.
45. Kolobow, T.1975. "Superior Blood Compatibility of Silicone Rubber Free of Silica Filler in Membrane Lung,"Trans. Am. Soci. Artif Organs, 21:587-593.
46.
46. Remy, M., L. Bordenavve, R. Bareille, R. Rouais, C. H. Baquey, U. Inserm, A. Gorodkov, E. S. Sidorenko and S. P. Novikova. 1994. "Endothelial Cell Compatibility Testing of Various Prosthetic Surfaces,"J. of Materials Science: Materials in Medicine, 5:808-813.
