Restricted accessResearch articleFirst published online 1995-10
Development of Artificial Skin (Template) and Influence of Different Types of Sterilization Procedures on Wound Healing Pattern in Rabbits and Guinea Pigs
Different types of sterilization procedures have been applied onto artificial skin (Template) developed in our laboratory from polyetherurethane, chitosan and polyvinyl alcohol, etc. Studies have been performed to investigate the differences in the wound healing pattern. It appears that quickened wound healing takes place in the rabbit model despite different types of samples and sterilization methods.
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References
1.
1. Rathinam, K. and C. P. Sharma. 1987. "Lectin Immobilized Albuminated Polyetherurethane Urea: Tissue Compatibility,"Current Science, 56:19-21.
2.
2. Travis, J., J. H. Harney and J. W. Thornton. 1987. "Modified Collagen Membrane as a Skin Substitute: Preliminary Studies,"J. Biomedical. Mater Res., 9:285-301.
3.
3. Quinn, K. J., J. M. Courtney,J. H. Evans,J. D. S. Gaylor and W. H. Reid. 1985. "Principles of Burn Dressings,"Biomaterials, 6:369-377.
4.
4. Forester, J. C., T. K. Hunt,T. C. Hayes and R. F. Pease. 1969. "Scanning Electron Microscopy of Healing Wounds,"Nature, 221:373-374.
5.
5. Peacock, E. E.1984. "Collagenolysis and the Biochemistry of Wound Healing,"Wound Repair, 3rd edition, Philadelphia, W. B. Saunders Co., pp. 102-104.
6.
6. Yannas, I. V. and J. F. Burke. 1975. "Correlation of in vivo Collagen Degradation Rate with in vitro Measurements,"J. Biomed. Mater Res., 9:623-628.
7.
7. Sharma, C. P. and K. Rathinam. 1986. "Surface Modification: Tissue Compatibility Towards Artificial Skin,"Proc. ACS. Div. Poly. Mater. Sci and Engg., Vol. 55, Fall Meeting, pp. 758-762.
8.
8. Sharma, C. P. and T. Chandy. 1987. "Protein Blended Chitosan Membranes for an Improved Hemodialysis,"Trans. Soc. Biomat., 10:31.
9.
9. Aleyamma, A. J. and C. P. Sharma. 1991. "Polyvinyl Alcohol as a Biomaterial,"Blood Compatible Materials and Devices: Perspectives Towards the 21st Century, C. P. Sharma and M. Szycher, eds., Lancaster, PA: Technomic Publishing Co., Inc., p. 126.
10.
10. Billingham, R. E. and P. S. Russel. 1956. "Studies on Wound Healing, with Special Reference to the Phenomenon of Contracture in Experimental Wounds in Rabbit Skin,"Annals of Surgery, 144:961-981.