A new original artificial connective matrix mainly made of elastin and fibrin-like product is used to reinforce damaged tissues and to close and restore a loss of substance in several domains of surgery: all sites in the digestive system and urinary tract; besides, it can substitute for the pericardium in iterative heart operations. In all cases, the original tissue is restored ad integrum while the biodegradable material disappears completely, without any complications.
Bell, E., S. Sher, B. Hull, C. Merill, S. Rosey, A. Charuson, D. Asselineau, L. Dubertret, B. Coulomb, C. Lafiere, B. Nusgens and Y. Neveux.1983. "The Reconstitution of Living Skin;' J. Invest. Dermatol, 81:2-10.
2.
Doilon, C.J. and F.H. Silver.1986. "Collagen-Base Wound Dressing: Ef. fects of Hialuronic Acid and Fibronectin on Wound Healing ," Biomater., 7:3-8.
3.
Harmand, M.F. , R. Duphil and P. Blanquet.1982. "Proteoglycan Synthesis in Chondrocyte Cultures from Osteo-Arthritic and Normal Articular Cartilage ;' Biochim. Biophys. Act., 717:190-202.
4.
Chignier, E. , R. Eloy, A. Huc, R. Gimeno and C. Gleizal.1985. " Long Term Behavior of Bovine Collagen Membrane Used as Vascular Substitute. Experimental Study in Rats," J. Biomed. Mater. Res., 19:115-131.
5.
Yannas, I.V. and J.F. Burke.1980. "Design of an Artificial Skin. I. Basic Design Principles," J. Biomed. Mater. Res. , 14:65-81.
6.
Jessen, C. and P. Sharma.1985. "Use of Fibrin Glue in Thoracic Surgery ;' Ann. Thorac. Surg., 39:521-524.
7.
Sheehan, S.J. , S.M. Rajah and R.C. Kester.1989. "Effect of Preclotting on the Porosity and Thrombogenicity of Knitted Dacron Grafts;' Biomater., 10:75-79.
Okada, M., B. Blombäck, M. Chang and B. Horowith.1985. "Fibronectin and Fibrin Gel Structure ," J. Biol. Chem., 260:1811-1820.
10.
Rabaud, M., F. Lefebvre, Y. Piquet, F. Belloc, J. Chevaleyre, M.F. Roudaut and H. Bricaud.1986. "Soluble Fibrinogen Derivatives Generated by Thrombin: Affinity for Elastin," Thromb. Res., 43:205-211.
11.
Rabaud, M., F. Lefebvre, M.T. Martin, M. Aprahamian, R. Schmitthaeusler and J.P. Cazenave.1987. "Adduct Formation between Soluble Fibrin Monomers and Elastin," Biomater., 8:217-222.
12.
Aprahamian, M., A. Lambert, G. Balboni, F. Lefebvre, R. Schmitthaeusler, C. Damge and M. Rabaud.1987. " A New Reconstituted Connective Tissue Matrix: Preparation, Biochemical, Structural and Mechanical Studies;' J. Biomed. Mat. Res., 21:965-977.
13.
Martin, M.T. , F. Lefebvre, P.V. Graves and M. Rabaud.1988. "Biochemical Study of Adduct Synthesis between Fibrin Monomers and Elastin," Biomater., 9:519-524.
14.
Barbie, C., C. Angibaud, T. Darnis, F. Lefebvre, M. Aprahamian and M. Rabaud.1989. "Some Factors Affecting Properties of Elastin-Fibrin Materials," Biomater., 10:445-448.
15.
Collet, D., F. Lefebvre, C. Quentin and M. Rabaud.1991. "In vitro Studies of Elastin-Fibrin Biomaterial Degradation: Preservative Effects of Protease Inhibitors and Antibiotics ," Biomater., 12:763-766.
16.
Collet, D., M. Rabaud, F. Lefebvre, B. Couderc, C. Quentin and J. Perissat. In press. "Evaluation of Elastin-Fibrin Biomaterial in Experimental Pancreatic Surgery," Mat. in Med..
17.
Riquet, M., F. Carnot, P. Gallix, D. Callise, F. Lefebvre and M. Rabaud.1990. "Biocompatibility of Elastin-Fibrin Material in the Rat," Biomater., 11:518-520.
18.
Rabaud, M., M. Aprahamian, C. Damgé, E. Loza, M. Wilhem, R. Schmitthaeusler and J. Marescaux.1987. Biomaterials and Clinical Applications . A. Pizzoferrato, P. G. Marchetti, A. Ravaglioli and A. J. C. Lee, eds., Amsterdam: Elsevier Science Publishers , pp. 453-457.
19.
Lefebvre, F. , F. Drouillet, A.M. Savin de Larclause, M. Aprahamian, D. Midy, L. Bordenave and M. Rabaud.1989. " Repair of Experimental Arteriotomy in Rabbit Aorta Using a New Resorbable Elastin Fibrin Biomaterial," J. Biomed. Mat. Res., 23:1423-1432.
20.
Cumming, J.A. , A.D. Cumming and J. Dawes.1989. " Urinary Elastase: The Contribution of the Lower Urinary Tract," Nephron, 53:376.
21.
Rabaud, M., F. Lefebvre and D. Ducassou.1991. "In vitro Association of Type III Collagen with Elastin and Its Solubilized Peptides," Biomater., 12:313-319.
22.
Lefebvre, F. , S. Gorecki, R. Bareille, J. Amédée, L. Bordenave and M. Rabaud.1992. " New Artificial Connective Matrix-Like Structure Made of Elastin Solubilized Peptides and Collagens: Elaboration, Biochemical and Structural Properties ," Biomater. , 13:28-33.
23.
Bordenave, L., F. Lefebvre, R. Bareille, F. Rouais, Ch. Baquey and M. Rabaud.1992. " New Artificial Connective Matrix-Like Structure: Thrombogenicity and Use as Endothelial Cell Culture Support," Biomater., 13:439-447.
