The blood compatibility of an artificial polymeric implant largely depends on the physicochemical nature of the polymer substrate. In the present study our aim is to develop an understanding of polymer surfaces having similar surface free energy, but different chemical characteristics. We attempted to graft hydrogels onto a silastic polyurethane (Angioflex) material and optimised the surface free energy to about 35.0 ergs/cm2. We compared the protein adsorption and platelet and lymphocyte adhesion on these surfaces. It is observed that there is a relative change in behavior because of the difference in chemical nature.
Get full access to this article
View all access options for this article.
References
1.
Baier, R.E., G.I. Loeb and G.T. Wattacc.1971. Fed. Proc., 30:1523.
2.
Lyman, D.J. and S.W. Kim.1971. Fed. Proc., 30:1658.
3.
Vroman, L., A.L. Adams, M. Klings, G.C. Fischer, P.S. Mcoz and R. Sokensky.1977. Ann. N.Y. Acad. Sci., 283:65.
4.
Lyman, D.J., J.L. Brash, S.W. Chakin, K.G. Klein and M. Carini.1968. Trans. Am. Soc. Artif. Intern. Organs , 24:250.
5.
Andrade, J.D. , H.B. Lee, M.S. John, S. W. Kim and J. W. Hibbs.1973. Trans. Am. Soc. Artif. Intern. Organs, 19:1.
6.
Sharma, C.P.1981. Biomaterials, 2:157.
7.
Sharma, C.P.1980. J. Sci. & Ind. Res. , 39:453.
8.
Sharma, C.P.1986. J. Colloid InterSci., 110(1):292.
9.
Kiremilci, M., A. Onch, A. Densili and E. Piskin.1986. Progress in Artificial Organs 1985, Y. Nose, C. Kjellstrand and P. Ivanovich, eds., Cleveland : ISAO Press, pp. 1010-1014.
10.
Jansen, B.J.1987. J. Biomaterials Applns., 1:502.
11.
Kaelble, D.K. and J. Moacanin.1977. Polymer, 8:475.
