Injection sclerotherapy has recently become a first-line treatment modality for bleeding varices of the esophagus. In this report the technique and complications, as well as the results of controlled and uncontrolled studies, are reviewed and discussed.
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References
1.
Graham DY, Smith L.The course of patients after variceal hemorrhage. Gastroenterology1981;80:800-809
2.
Conn HOEndoscopic sclerotherapy: an analysis of variants. Hepatology1983;3:769-771
3.
Williams KGD , Dawson JLFiberoptic injection of oesophageal varices . Br Med J1974;2:766-767
4.
Clark AW, Westaby D., MacDugall BRD, et al. Prospective controlled trial of injection sclerotherapy in patients with cirrhosis and recent variceal hemorrhage. Lancet1980;2:552-554
5.
Spence RAJ , Anderson JR, Johnston GWTwenty-five years of injection sclerotherapy . Br J Surg1985; 72:195-198
6.
Paquet KJ, Feussner H.Endoscopic sclerosis and esophageal balloon tamponade in acute hemorrhage from esophagogastric varices: a prospective controlled randomized trial. Hepatology1985;5:580-583
7.
Hughes RW, Larson DE, Viggiano TR, et al. Endoscopic variceal sclerosis: a one year experience. Gastrointest Endosc1982;28:62-66
8.
Lewis J., Chung RS, Allison J.Sclerotherapy of esophageal varices. Arch Surg1980;115:476-480
9.
Lewis JW, Chung RS, Allison JGInjection sclerotherapy for control of acute variceal hemorrhage. Am J Surg1981;142:592-595
10.
Westaby D., MacDougall BRD, Melia W., et al. A prospective randomized study of two sclerotherapy techniques for esophageal varices. Hepatology1983; 3:681-684
Jensen DM, Silpa ML, Tapia JI, et al. Comparison of different methods for endoscopic hemostasis of bleeding canine esophageal varices. Gastroenterology1983;84:1455-1461
13.
Jensen DMSclerosants for injection sclerosis of esophageal varices. Gastrointest Endosc1983;29: 315-317
14.
Brooks WS Jr.Variceal sclerosing agents. Am J Gastroenterol1984;79:424-428
15.
Soderlund C.Variceal hemorrhage. A study of unselected patients with massive bleeding from esophageal varices. Acta Chir Scand1982;148:275-280
16.
Kjaergaard J., Fischer A., Miskowiak J.Sclerotherapy of bleeding esophageal varices. Long term results. Scand J Gastroenterol1982 ;17:363-367
17.
Fleig WE, Stange EF, RueHenauer K., et al. Emergency endoscopic sclerotherapy for bleeding esophageal varices: a prospective study in patients not responding to balloon tamponade. Gastrointest Endosc1983;29:8-14
18.
Westaby D., Melia WM, MacDougall BRD, et al. Injection sclerotherapy of esophageal varices. A prospective randomized trial of different treatment schedules. Gut1984;25:129-132
19.
Chung RS, Lewis JW, Camara DSA technique of sclerotherapy. Surg Gastroenterol1983;2:303-309
20.
Grobe JL, Kozarek RA, Sanowski RA, et al. Venography during endoscopic injection sclerotherapy of esophageal varices. Gastrointest Endosc1984;30:6-8
21.
Sukigara M. , Omoto R., Miyamae T.Systemic dissemination of ethanolamine oleate after injection sclerotherapy for esophageal varices . Arch Surg1985;120:833-836
22.
Bailey-Newton RS, Connors AF, Bacon BR Effect of endoscopic variceal sclerotherapy on gas exchange and hemodynamics in humans. Gastroenterology1985;89:368-373
23.
Camara DS, Caruana JA Jr, Chung RS, et al. The hemodynamic effects of the sclerosant sodium morrhuate in dogs. Surg Gynecol Obstet1985;161:327-331
Conn HOIdeal treatment of portal hypertension in 1985. Clin Gastroenterol1985;14:259-288
26.
MacDougall BRD , Theodossi A., Westaby D., et al. Increased long term survival in variceal hemorrhage using injection sclerotherapy. Results of a controlled trial. Lancet1982;1:124-127
27.
Terblanche J., Kahn D., Campbell JAH, et al. Failure of repeated injection sclerotherapy to improve long term survival after oesophageal variceal bleeding. Lancet1983;2:1328-1332
28.
Cello JP, Grendell JH, Crass RA, et al. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and variceal hemorrhage. N Engl J Med1984;311:1589-1594
29.
The Copenhagen Esophageal Varices Sclerotherapy Project.Sclerotherapy after first variceal hemorrhage in cirrhosis. A randomized multicenter trial. N Engl J Med1984;311:1594-1600
30.
Paquet KJProphylactic endoscopic sclerosing treatment of the esophageal wall in varices. A prospective controlled randomized trial. Endoscopy1982;14:4-5
31.
Witzel L., Wolbergs E., Merki H.Prophylactic endoscopic sclerotherapy of oesophageal varices. A prospective controlled study. Lancet1985;1:773-775
32.
Camara DSBacteremia and sclerotherapy of esophageal varices. Arch Intern Med1986;146:458-459
33.
Camara DS, Gruber M., Barde CJ, et al. Transient bacteremia following endoscopic injection sclerotherapy . Arch Intern Med1983;143:1350-1352
Sorensen T. , Burcharth F., Pedersen MLOesophageal stricture and dysphagia after endoscopic sclerotherapy for bleeding varices. Gut1984;25:473-477
36.
Bacon BR, Bailey-Newton RS, Connors AF Jr.Exudative pleural effusions after endoscopic variceal sclerotherapy . Gastroenterology1985;88:1910-1914
37.
Paquet KJ, Oberhammer E.Sclerotherapy of bleeding oesophageal varices by means of endoscopy . Endoscopy1978;10:7-12
38.
Soderlund C. , Wiechel KLOesophageal perforation after sclerotherapy for variceal hemorrhage. Acta Chir Scand1983 ;149:491-495
39.
Wesdorp I., Bartelsman Jfwm, Huibregtse K., et al. Treatment of instrumental oesophageal perforation. Gut1984;25:398-404
40.
Goodale RL, Silvis SE, O'Leary JF, et al. Early survival after sclerotherapy for bleeding esophageal varices . Surg Gynecol Obstet1982;155:523-528
41.
Alwmark A., Bengmark B., Borjesson B.Emergency and long term transesophageal sclerotherapy of bleeding esophageal varices. Scand J Gastroenterol1982;17:409-412
42.
Barsoum MS, Bolous FI, El-Rooby AA, et al. Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices. Br J Surg1982;69:76-78
43.
Korula J., Balart LA, Raduan G., et al. A prospective randomized controlled trial of chronic esophageal variceal sclerotherapy. Hepatology1985;5:584-589
44.
Reilly JJ Jr, Schade RR, VanThiel DSEsophageal function after injection sclerotherapy. Pathogenesis of esophageal stricture. Am J Surg1984;147:85-88
