Barbiturate Therapy and Nutritional Support in Head-Injured Patients

Abstract

A major goal of therapy after acute head injury is to prevent increased intracranial pressure. Treatments of intracranial pressure include measures such as hyperventilation, ventricular catheters, hypothermia, osmotic dehydration, sedatives, and in some cases, steroids. If these measures are not effective, barbiturate therapy is used to reduce brain metabolism, decrease cerebral blood flow, and suppress responses to stimulation. Barbiturates produce central nervous system effects that decrease gastrointestinal tone and motility. Clinicians must consider the specific effects of barbiturates and the unique nutritional needs of head-injured patients in order to select effective nutritional support regimens.

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