Parenteral nutrition can be a life-saving therapy, but its benefits need to
be balanced with a unique set of risks and complications. Methods of practice
vary because there is a dearth of research in the area of pediatric parenteral
nutrition. This article reviews the available literature on parenteral
nutrition in children and provides suggestions on prevention and management of
parenteral nutrition–associated liver disease. Some of the issues
discussed in this article include glucose infusion rates, cycling of
parenteral nutrition, copper and manganese toxicity, and the provision of
glutamine, selenium, and carnitine.
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