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Abstract

The reactive and reparative capacity of injured tissue when treated with either Pulsed Electromagnetic Fields (PEMFs) or with immunomodulator drugs (Prostaglandin E2 and Thymopentin) was evaluated. A morphological and quantitative evaluation was made of the interactions and the interferences on the structural stages of tissue repair processes. When PEMFs were used the time required for new tissue to completely cover the wound was 26 days after surgery, instead of 30 days for control conditions or for treatment with PGE₂ or Thymopentin. PEMFs showed accelerated healing process. Both PGE₂ and Thymopentin should be considered, in association with other drugs, in an attempt to strengthen the various immunomodulative phases of the reconstitution of injured tissue.

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Biological Effects of Tissue Modulations in Wound Healing

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