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Abstract

The investigation of vocal folds viscoelastic properties in an animal model (rabbit) after injection of various augmentation substances, 6 months after injection, is reported. The injected materials were: hyaluronan-based materials (Hylan B gel and Deflux^®), cross-linked collagen (Zyplast^®) and polytetrafluoroethylene (Teflon^®). Rheological properties of the augmentation substances were also evaluated. The results from these animal experiments indicate that the viscoelastic properties of the vocal folds injected with Deflux^®, Zyplast^® and Hylan B gel are similar to the healthy vocal folds (non-injected samples) used as control, thus demonstrating that these materials are good candidates for further studies aimed at restoring/preserving the vibratory capacity of the vocal folds with injection treatment in glottal insufficiency.

Keywords

viscoelasticity vocal folds injection augmentation hyaluronan

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Rheological Characterization of Vocal Folds after Injection Augmentation in a Preliminary Animal Study

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