Felbamate for Refractory Infantile Spasms

Aicardi J. : Epilepsy in Children. Infantile Spasms and Related Syndromes. New York, Raven Press, 1986, pp 17-38.

Cowan LD , Hudson LS : The epidemiology and natural history of infantile spasms. J Child Neurol 1991;16:355-364.

Faught E. , Sachdeo RC , Remler MP , et al: Felbamate monotherapy for partial onset seizures. An active control trial. Neurology 1993;43: 688-692.

The Felbamate Study Group in Lennox-Gastaut Syndrome : Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). N Engl J Med 1993 ;328:29-33.

Altman DG : Practical Statistics forMedical Research. Chapman and Hall , 1995.

Leppik IE , Dreiffus FE , Pledger GW , et al: Felbamate for partial seizures: Results of a controlled trial . Neurology 1991;41:1785-1789.

Sachdeo R. , Kramer LD , Rosenberg A. , Sachdeo S. : Felbamate monotherapy: Controlled trial in patients with partial onset seizures . Ann Neurol 1992;32:386-392.

Bourgeosis B. , Leppik IE , Sackellares JC , et al: Felbamate: A double blind controlled trial in patients undergoing pre-surgical evaluation for partial seizures . Neurology 1993;43:693-696.

Carter Wallace advisory letter re felbamate and potential for aplastic anemia, August 1994.

Carter Wallace advisory letter re felbamate and potential hepatoxicity , September 1994.

Riikonen R. , Donner M. : ACTH therapy in infantile spasms. Side effects . Arch Dis Child 1980;55:664-672.

Dreiffus F. , Langer D. , Moline K. , Maxwell J. : Valproic acid hepatic fatalities II. US experience since 1984. Neurology 1989;39:201-207.

Espe-Lillo J. , Ritter R. , Frost M. : Safety and efficacy of felbamate in infantile spasms, abstract. Epilepsia 1993;34(Suppl 6):110.