This study describes the differences between several quantifiable variables that characterize interictal sharp EEG transients (SETS) recorded from neurologically ill neonates with proven electrographic seizures and a comparison group of apparently neurologically well babies with no known seizures. The abundance (number of sharp EEG transients per ten minutes), waveform morphology, repetitive behavior, and spatial distribution of SETS provide interpretive guidelines that help discriminate between these two patient populations (J Child Neurol 1989;4:30-38).
Get full access to this article
View all access options for this article.
References
1.
Goddard J. , Glaze DG, Fishman MA: Neurological disorders of the neonate, in Appel SH (ed): Current Neurology . New York , John Wiley & Sons, 1982, pp 241-261.
2.
Nelson KB, Broman SH: Perinatal risk factors in children with serious motor and mental handicaps . Ann Neurol1977 ;2:371-377.
3.
Fenichel GM, Fitzpatrick JE: Difficulty in clinical identification of neonatal seizures: An EEG monitor study (abstract). Electroencephalogr Clin Neurophysiol1984;58:33P.
4.
Mizrahi EM , Kellaway P.: Characterization of seizures in neonates and young infants by time-synchronized EEG/polygraphic/video monitoring (abstract) . Ann Neurol1984;16:383.
5.
Shewmon DA : Dissociation between cortical discharges and ictal movements in neonatal seizures (abstract). Ann Neurol1983;14:368.
6.
Sarnat HG : Pathogenesis of decerebrate "seizures" in the premature infant with intraventricular hemorrhage. J Pedriatr1975 ;87:154-155.
7.
Rowe JC, Holmes GL, Hafford J., et al: Prognostic value of the electroencephalogram in term and preterm infants following neonatal seizures. Electroencephalogr Clin Neurophysiol1985;60: 183-196.
8.
Monod N., Pajot N., Guidasci S.: The neonatal EEG: Statistical studies and prognostic value in full-term and preterm babies. Electroencephalogr Clin Neurophysiol1972;32:529-544.
9.
Rose AL, Lombroso CT: Neonatal seizure states. Pediatrics1970;45:404-424.
10.
Watanabe K. , Hara K., Miyazaki S., et al: Electroclinical studies of seizures in the newborn. Folia Psychiatr Neurol Jpn1977;31: 383-392.
11.
Hughes JR, Fino J., Gagnon L.: The use of electroencephalogram in the confirmation of seizures in premature and neonatal infants. Neuropediatrics1983 ;14:213-219.
12.
Clancy RR, Spitzer AR: Cerebral cortical function in infants at risk for sudden infant death syndrome . Ann Neurology1985;18: 41-47.
13.
Tharp BR : Neonatal electroencephalography, in Korobkin R, Guilleminault C (eds): Progress in Perinatal Neurology . Baltimore , Williams & Wilkins, 1981 , pp 31-64.
14.
Clancy RR, Tharp BR, Enzman D.: EEG in premature infants with intraventricular hemorrhage. Neurology1984;34:583-590.
15.
Clancy RR, Legido A., Lewis D.: The effects of mental status and ictal duration on the clinical visibility of EEG-proven neonatal seizures (abstract). Ann Neurol1986;20:411.
16.
Kellaway P., Hrachovy RA: Status epilepticus in newborns: A perspective on neonatal seizures , in Delgado AV, Wasterlain CG, Treiman DM , Porter RJ (eds): Advances in Neurology , vol 34. New York, Raven Press, 1983.
17.
Watanabe K. , Negoro T., Inakuma K., Yamazaki T.: Subclinical delta status in the newborn—an unfavorable prognostic sign. Clin Electroencephalogr1984;15:125-131.
18.
Karbowski K. , Nencka A.: Right mid-temporal sharp EEG transients in healthy newborns. Electroencephalogr Clin Neurophysiol1980;48:461-469.
19.
Kaplan RE, Lacey DJ: Benign familial neonatal—infantile seizures. Am J Med Genet1983;16:595-599.
20.
Pettit RE, Fenichel GM: Benign familial neonatal seizures. Arch Neurol1980;37:47-48.
21.
Archibald JE , Drazkowski JF: Cranial applications of compressed spectral analysis (CSA) in OR/ICU settings. Am J EEG Technol1985;25:13-36.
22.
Bridgers SL , Ebersole JS, Ment LR, et al: Cassette electroencephalography in the evaluation of neonatal seizures. Arch Neurol1986;43:49-51.
23.
Tharp BR, Laboyrie PM: The incidence of EEG abnormalities and outcome of infants paralyzed with neuromuscular blocking agents. Crit Care Med1983;11:926-929.
