Studies investigating the possible benefits of transcranial direct current stimulation on left dorsolateral prefrontal cortex in children and adolescents with attention-deficit hyperactivity disorder (ADHD) have not been performed. This study assesses the effect of transcranial direct current stimulation in children and adolescents with ADHD on neuropsychological tests of visual attention, visual and verbal working memory, and inhibitory control. An auto-matched clinical trial was performed involving transcranial direct current stimulation in children and adolescents with ADHD, using SNAP-IV and subtests Vocabulary and Cubes of the Wechsler Intelligence Scale for Children III (WISC-III). Subjects were assessed before and after transcranial direct current stimulation sessions with the Digit Span subtest of the WISC-III, inhibitory control subtest of the NEPSY-II, Corsi cubes, and the Visual Attention Test (TAVIS-3). There were 9 individuals with ADHD according to Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) criteria. There was statistically significant difference in some aspects of TAVIS-3 tests and the inhibitory control subtest of NEPSY-II. Transcranial direct current stimulation can be related to a more efficient processing speed, improved detection of stimuli, and improved ability to switch between an ongoing activity and a new one.
HarpinVA. The effect of ADHD on the life of an individual, their family, and community from preschool to adult life. Arch Dis Child. 2005;90(suppl 1):i2–i7.
2.
ArnoldLEHodgkinsPKahleJMadhooMKewleyG. Long-term outcomes of ADHD: academic achievement and performance. J Atten Disord. 2015112.
3.
MannuzzaSKleinRG. Long-term prognosis in attention-deficit hyperactivity disorder. Child Adolesc Psychiatr Clin N Am. 2000;9:711–726.
4.
BarbaresiWJKatusicSKColliganRC. How common is attention-deficit hyperactivity disorder? Incidence in a population-based birth cohort in Rochester, Minn. Arch Pediatr Adolesc Med. 2002;156:217–224.
5.
NaradMEGarnerAAAntoniniTN. Negative consequences of poor driving outcomes reported by adolescents with and without ADHD. J Atten Disord. 2015316.
6.
ParkJKimB. Comorbidity and factors affecting treatment non-persistence in ADHD. J Atten Disord. 2015525.
7.
LangleyKFowlerTFordT. Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. Br J Psychiatry. 2010;196:235–240.
8.
FaraoneSVBiedermanJMickE. The age-dependent decline of attention-deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med. 2006;36:159–165.
9.
CheungCHRijdijkFMcLoughlinGFaraoneSVAshersonPKuntsiJ. Childhood predictors of adolescent and young adult outcome in ADHD. J Psychiatr Res. 2015;62:92–100.
10.
PolanczykGVWillcuttEGSalumGAKielingCRohdeLA. ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis. Int J Epidemiol. 2014;43:434–442.
11.
KooijJJBuitelaarJKvan den OordEJFurerJWRijndersCAHodiamontPP. Internal and external validity of attention-deficit hyperactivity disorder in a population-based sample of adults. Psychol Med. 2005;35:817–827.
12.
PolanczykGde LimaMSHortaBLBiedermanJRohdeLA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry. 2007;164:942–948.
13.
TrippGWickensJR. Neurobiology of ADHD. Neuropharmacology. 2009;57:579–589.
14.
KooijSJBejerotSBlackwellA. European consensus statement on diagnosis and treatment of adult ADHD: the European Network Adult ADHD. BMC Psychiatry. 2010;10:67.
15.
BushGValeraEMSeidmanLJ. Functional neuroimaging of attention-deficit hyperactivity disorder: a review and suggested future directions. Biol Psychiatry. 2005;57:1273–1284.
16.
KielingCGoncalvesRRTannockRCastellanosFX. Neurobiology of attention-deficit hyperactivity disorder. Child Adolesc Psychiatr Clin N Am. 2008;17:285–307, viii.
17.
AshersonP. Clinical assessment and treatment of attention-deficit hyperactivity disorder in adults. Expert Rev Neurother. 2005;5:525–539.
18.
KendallTTaylorEPerezATaylorC. Diagnosis and management of attention-deficit hyperactivity disorder in children, young people, and adults: summary of NICE guidance. BMJ. 2008;337:a1239.
19.
GrahamJBanaschewskiTBuitelaarJ. European guidelines on managing adverse effects of medication for ADHD. Eur Child Adolesc Psychiatry. 2011;20:17–37.
20.
CosmoCBaptistaAFde AraujoAN. A randomized, double-blind, sham-controlled trial of transcranial direct current stimulation in attention-deficit hyperactivity disorder. PLoS One. 2015;10:e0135371.
21.
BunseTWobrockTStrubeW. Motor cortical excitability assessed by transcranial magnetic stimulation in psychiatric disorders: a systematic review. Brain Stimul. 2013;7:158–169.
22.
LuCWeiYHuRWangYLiKLiX. Transcranial direct current stimulation ameliorates behavioral deficits and reduces oxidative stress in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson’s disease. Neuromodulation. 2015;18:442–446.
23.
BatistaEKKlaussJFregniFNitscheMANakamura-PalaciosEM. A randomized placebo-controlled trial of targeted prefrontal cortex modulation with bilateral tDCS in patients with crack-cocaine dependence. Int J Neuropsychopharmacol. 2015;18.
24.
KoopsSvan den BrinkHSommerIE. Transcranial direct current stimulation as a treatment for auditory hallucinations. Front Psychol. 2015;6:244.
25.
Val-LailletDAartsEWeberB. Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity. Neuroimage Clin. 2015;8:1–31.
26.
Pereira Junior BdeSTortellaGLaferB. The Bipolar Depression Electrical Treatment Trial (BETTER): design, rationale, and objectives of a randomized, sham-controlled trial and data from the pilot study phase. Neural Plast. 2015;2015:684025.
27.
SabaGMoukheiberAPelissoloA. Transcranial cortical stimulation in the treatment of obsessive-compulsive disorders: efficacy studies. Curr Psychiatry Rep. 2015;17:36.
28.
NowakDAGrefkesCAmeliMFinkGR. Interhemispheric competition after stroke: brain stimulation to enhance recovery of function of the affected hand. Neurorehabil Neural Repair. 2009;23:641–656.
29.
KrishnanCSantosLPetersonMDEhingerM. Safety of noninvasive brain stimulation in children and adolescents. Brain Stimul. 2015;8:76–87.
30.
AndradeACMagnavitaGMAllegroJVNetoCELucena RdeCFregniF. Feasibility of transcranial direct current stimulation use in children aged 5 to 12 years. J Child Neurol. 2014;29:1360–1365.
31.
NitscheMACohenLGWassermannEM. Transcranial direct current stimulation: State of the art 2008. Brain Stimul. 2008;1:206–223.
32.
LoftusAMYalcinOBaughmanFDVanmanEJHaggerMS. The impact of transcranial direct current stimulation on inhibitory control in young adults. Brain Behav. 2015;5:e00332.
33.
SpieserLvan den WildenbergWHasbroucqTRidderinkhofKRBurleB. Controlling your impulses: electrical stimulation of the human supplementary motor complex prevents impulsive errors. J Neurosci. 2015;35:3010–3015.
34.
KrauseBCohen KadoshR. Can transcranial electrical stimulation improve learning difficulties in atypical brain development? A future possibility for cognitive training. Dev Cogn Neurosci. 2013;6:176–194.
35.
Demirtas-TatlidedeAVahabzadeh-HaghAMPascual-LeoneA. Can noninvasive brain stimulation enhance cognition in neuropsychiatric disorders?Neuropharmacology. 2013;64:566–578.
OliveiraJFZanaoTAValiengoL. Acute working memory improvement after tDCS in antidepressant-free patients with major depressive disorder. Neurosci Lett. 2013;537:60–64.
38.
BoggioPSBermpohlFVergaraAO. Go-no-go task performance improvement after anodal transcranial DC stimulation of the left dorsolateral prefrontal cortex in major depression. J Affect Disord. 2007;101:91–98.
39.
BrunoniARAmaderaJBerbelBVolzMSRizzerioBGFregniF. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int J Neuropsychopharmacol. 2011;14:1133–1145.
40.
BushG. Attention-deficit hyperactivity disorder and attention networks. Neuropsychopharmacology. 2010;35:278–300.
41.
KrauseBCohen KadoshR. Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation. Front Syst Neurosci. 2014;8:25.
42.
RiddingMCZiemannU. Determinants of the induction of cortical plasticity by non-invasive brain stimulation in healthy subjects. J Physiol. 2010;588(pt 13):2291–2304.
43.
BakerJMRordenCFridrikssonJ. Using transcranial direct-current stimulation to treat stroke patients with aphasia. Stroke. 2010;41:1229–1236.
44.
Muller-DahlhausFZiemannU. Metaplasticity in human cortex. Neuroscientist. 2015;21:185–202.
