We describe the magnetic resonance imaging findings of a 4 month old infant with hypohidrotic ectodermal dysplasia who developed heat stroke. Magnetic resonance imaging of the brain revealed signal alteration with restricted diffusion in the splenium of corpus callosum, cerebral peduncles and cerebellar dentate nuclei.
DiFazioMPLevinSDepperM. Ectodermal dysplasia and brain cystic changes: confirmation of a novel neurocutaneous syndrome. J Child Neurol. 2002;17:475–478.
2.
SoekarmanDFrynsJP. Hypohidrotic ectodermal dysplasia, central nervous system malformation, and distinct facial features: confirmation of a distinct entity?J Med Genet. 1993;30:245–247.
3.
LeeJSChoiJCKangSY. Heat stroke: increased signal intensity in the bilateral cerebellar dentate nuclei and splenium on diffusion-weighted MR imaging. Am J Neuroradiol. 2009;30:E58.
4.
OokuraRShiroYTakaiT. Diffusion-weighted magnetic resonance imaging of a severe heat stroke patient complicated with severe cerebellar ataxia. Intern Med. 2009;48:1105–1108.
5.
PrasunPKarmarkarSAAgarwalA. Unusual physical features and heat stroke presentation for hypohydrotic ectodermal dysplasia. Clin Dysmorphol. 2012;21:24–26.
6.
KimENaDGKimEY. MR imaging of metronidazole-induced encephalopathy: lesion distribution and diffusion-weighted imaging findings. Am J Neuroradiol. 2007;28:1652–1658.
