The authors describe 2 female cousins with neonatal stroke. One was heterozygous for the plasminogen activator inhibitor-1 4G variant and compound heterozygous for the A1298C and C677T methylenetetrahydrofolate reductase mutations. Her cousin was homozygous for the plasminogen activator inhibitor-1 4G variant and heterozygous for the methylenetetrahydrofolate reductase A1298C and factor V Leiden mutations.
Golomb MRThe contribution of prothrombotic disorders to peri- and neonatal ischemic stroke. Semin Thromb Hemost. 2003;29:415-424.
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Golomb MR, Garg BP, Walsh LE, Williams LSPerinatal stroke in baby, prothrombotic gene in mom: does this affect maternal health insurance?Neurology. 2005;65:13-16.
