Barth syndrome is an inherited disorder characterized by dilated cardiomyopathy, neutropenia, growth retardation, and skeletal myopathy. We describe a case of acute stroke owing to Barth syndrome that required intra-arterial thrombolysis. This case suggests that cardiovascular complications can be observed in patients with Barth syndrome. Stroke prevention measures, including the use of antithrombotic agents, might be warranted. (J Child Neurol 2006;21:805—807; DOI 10.2310/7010.2006.00177).
Get full access to this article
View all access options for this article.
References
1.
Barth PG, Scholte HR, Berden JA, et al: An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes. JNeurol Sci1983;62:327—355.
2.
Kelley RI, Cheatham JP, Clark BJ, et al: X-linked dilated cardiomyopathy with neutropenia, growth retardation, and 3-methylglutaconic aciduria. J Pediatr1991;119:738—747.
3.
Bione S., D'Adamo P., Maestrini E., et al: A novel X-linked gene, G4.5, is responsible for Barth syndrome . Nat Genet1996;12:385—389.
