Birth asphyxia can be an early sign of cerebral palsy, the effect of an antenatal anomaly rather than its cause. The objective of this study was to evaluate the occurrence of intrapartum complications in patients with malformation of cortical development. The data were retrospectively assessed and compared with a control group of children with idiopathic epilepsy. Intrapartum complications were reported in 22 (31.5%) patients, as opposed to only 2 in the control group (p<0.001). Patients with cortical malformations frequently present intrapartum complications, which could lead to the misdiagnosis of hypoxic-ischemic encephalopathy. (J Child Neurol 2005;20:675—678).
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References
1.
Mandelbaum DE, Paneth N.: Pediatric neurology: Cerebral palsy, in De Vivo DC, Percy AK (eds): Continuum: Lifelong Learning in Neurology. Philadelphia , Saunders, Volume 6:8—30, 2000.
2.
Blair E., Stanley F., Hockey A.: Intrapartum asphyxia and cerebral palsy. J Pediatr1992;121:170—171.
3.
Nelson KB, Ellenberg J.: Antecedents of cerebral palsy: Multi-variate analysis of risk. N Engl J Med1986;315:81—86.
4.
Grant A., O'Brien N., Joy MT, et al: Cerebral palsy among children born during the Dublin randomised trial of intrapartum monitoring. Lancet1989 ;2:1233—1236.
5.
Nelson KB, Ellenberg J.: Obstetric complications as risk factors for cerebral palsy or seizure disorders . JAMA1984;251:1843—1848.
6.
Adamson SJ, Alessandri LM, Badawi N., et al: Predictors of neonatal encephalopathy in full-term infants. BMJ1995;311:598—602.
7.
Stanley FJ: The aetiology of cerebral palsy. Early Hum Dev1994;36:81—88.
8.
Freud S.: Die infantile Cerebrallähmung, in H Nothnagel (ed): Specielle Pathologie 9, Teil 3 (1. Hälfte). Wien, Holder, 1897, 1—327.
9.
Barkovich AJ , Kuzniechy R., Jackson GD, et al: Classification system for malformations of cortical development. Neurology2001;57:2168—2178.
10.
Montenegro MA, Guerreiro MM, Lopes-Cendes I., et al: Interrelationship of genetics and prenatal injury in the genesis of malformations of cortical development. Arch Neurol2002;59:1147—1153.
11.
Rakic P.: Defects of neuronal migraton and the pathogenesis of cortical malformations , in Boer GJ, Feenstra MGP, Mirmiran M, et al (editors): Progress in Brain Research, vol 73. Amsterdam, Elsevier, 1988, 15—37.
12.
Volpe JJ: Hypoxic-ischemic encephalopathy: Clinical aspects, in Volpe JJ (editor): Neurology of the Newborn, 4th ed. Philadelphia, Saunders, 2001, 331—394.
13.
Bax M.: Terminology and classification of cerebral palsy. Dev Med Child Neurol1964;6:295—297.
14.
Kurland LT: Definitions of cerebral palsy and their role in epidemiologic research. Neurology1957;7:651—654.
15.
Nelson KB, Ellenberg JH: Epidemiology of cerebral palsy. Adv Neurol1978;19:421—435.
16.
Wharton RH, Bresnan MJ: Neonatal respiratory depression and delay in diagnosis in Prader-Willi syndrome . Dev Med Child Neurol1989;31:231—236.
Harper RG, Greenberg M., Farahani G., et al: Fetal movement, biochemical and biophysical parameters, and the outcome of pregnancy. Am J Obstet Gynecol1981;141:39—42.
19.
McNay MB: Fetal movements. Dev Med Child Neurol1988 ;30: 821—824.
20.
Moore TR, Piacquadio K.: A prospective evaluation of fetal movement screening to reduce the incidence of antepartum fetal death. Am J Obstet Gynecol1989;160:1075—1080.
21.
Niswander K. , Elbourne D., Redman C., et al: Adverse outcome of pregnancy and the quality of obstetric care. Lancet1984;2:827—830.
