Breathing is Not An Option;Dyspnea is

Raghu G. , Collard H.R. , Egan J.J. An official ATS/ERS/JRS/ ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011; 183(6): 788–824. doi: 10.1164/rccm.2009-040GL.

Lee J.S. , McLaughlin S. , Collard H.R. Comprehensive care of the patient with idiopathic pulmonary fibrosis. Curr Opin Pulm Med 2011; 17(5): 348–354. doi: 10.1097/MCP.0b013e328349721b;10.1097/MCP.0b013e328349721b.

Nishiyama O. , Taniguchi H. , Kondoh Y. A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis. Eur Respir J 2010; 36(5): 1067–1072. doi: 10.1183/09031936.00152609.

Smith A.K. , McCarthy E. , Weber E. Half of older Americans seen in emergency department in last month of life; most admitted to hospital, and many die there. Health Aff (Millwood) 2012; 31(6): 1277–1285. doi: 10.1377/hlthaff.2011.0922.

Garcia-Polo C. , Alcázar-Navarrete B. , Ruiz-Iturriaga L.A. Factors associated with high healthcare resource utilisation among COPD patients. Respir Med 2012; 106(12): 1734–1742. doi: 10.1016/j.rmed.2012.09.009.

Horton R. Reducing emergency room utilization in end-stage COPD — feasible or fantasy? Chron Respir Dis 2013; 10(1): 49–54. doi: 10.1177/1479972312471550.

Marciniuk D.D. , Goodridge D. , Hernandez P. Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a Canadian thoracic society clinical practice guideline. Can Respir J 2011; 18(2): 69–78.

Bajwah S. , Ross J.R. , Peacock J.L. Interventions to improve symptoms and quality of life of patients with fibrotic interstitial lung disease: a systematic review of the literature. Thorax 2013; 68(9): 867–879. doi: 10.1136/thoraxjnl-2012-202040.

Lanken P.N. , Terry P.B. , Delisser H.M. An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses. Am J Respir Crit Care Med 2008; 177(8): 912–927. doi: 10.1164/rccm.200605-587ST.

Bruera E. , Kuehn N. , Miller M.J. The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients. J Palliat Care 1991; 7(2): 6–9.

Harlos M. Palliative care incident pain and incident dyspnea protocol. Winnipeg: Palliative.info; 2002. Accessed June 23, 2014. http://palliative.info/IncidentPain.htm

Gika M. , Eguchi K. , Inoue Y. [Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl injection, and oxycodone hydrochloride.] Gan To Kagaku Ryoho 2010; 37(3): 547–550. [Japanese]

O'Donnell D.P. , Schafer L.C. , Stevens A.C. Effect of introducing the mucosal atomization device for fentanyl use in out-of-hospital pediatric trauma patients. Prehosp Disaster Med 2013; 28(5): 520–522. doi: 10.1017/S1049023X13003579.

Sitte T. [Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care — overview and case report.] Wien Med Wochenschr 2009; 159(23-24): 566–570. doi: 10.1007/s10354-009-0724-2 [German]

Cleveland Clinic. Living with pulmonary hypertension: dietary and lifestyle changes. Cleveland: Cleveland Clinic; 1995–2011. Accessed June 23, 2014. http://my.clevelandclinic.org/dis-orders/pulmonary_hypertension/hic_living_with_pulmonary_hypertension_dietary_and_lifestyle_changes.aspx

Switzer C. Exercise and pulmonary hypertension. San Francisco: PHCentral; 1998–2012. Accessed June 23, 2014. www.phcentral.org/features/exercise-and-pulmonary-hypertension

American Heart Association. Pulmonary hypertension. Dallas: American Heart Association; 2012. Accessed June 23, 2104. www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/TheImpactofCongenitalHeartDefects/Pulmonary-Hypertension_UCM_307044_Article.jsp

Swigris J.J. , Kuschner W.G. , Jacobs S.S. Health-related quality of life in patients with idiopathic pulmonary fibrosis: a systematic review. Thorax 2005; 60(7): 588–594. doi: 10.1136/thx. 2004.035220.

Bushnaq M. , Al-Shoubaki M. , Milhem M. The feasibility of using intravenous fentanyl as sublingual drops in the treatment of incidental pain in patients with cancer. J Palliat Med 2009; 12(6): 511–514. doi: 10.1089/jpm.2009.9618.

Tennant F. , Hermann L. Self-treatment with oral transmucosal fentanyl citrate to prevent emergency room visits for pain crises: patient self-reports of efficacy and utility. J Pain Palliat Care Pharmacother 2002; 16(3): 37–44.

Ekstrom M.P. , Bornefalk-Hermansson A. , Abernethy A.P. Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study. BMJ 2014; 348: g445. doi: 10.1136/bmj.g445.

Mularski R.A. , Reinke L.F. , Carrieri-Kohlman V. An official American Thoracic Society workshop report: assessment and palliative management of dyspnea crisis. Ann Am Thorac Soc 2013; 10(5): S98–106. doi: 10.1513/AnnalsATS.201306–169ST.