Abstract
Background:
High-definition liposuction (HDL) has evolved to incorporate multiple energy-based technologies designed to enhance adipose removal while promoting skin and soft tissue contraction. These technologies commonly include ultrasound-assisted liposuction and helium plasma-based radiofrequency skin tightening, both frequently applied over extensive surface areas in a circumferential fashion. Although these modalities significantly improve outcomes over traditional body contouring techniques, their combined use may generate a cumulative inflammatory response that predisposes certain patients to hyperinflammatory fibrosis.
Objective:
This article reviews the pathophysiology of hyperinflammatory fibrosis, identifies HDL-specific risk factors, and proposes preventive and management strategies.
Methods:
We discuss contributory factors associated with the development of hyperinflammatory fibrosis following HDL, including cumulative energy delivery, mechanical tissue trauma, lymphatic disruption, preexisting skin and soft tissue redundancy, and prolonged postoperative edema.
Results:
Comprehensive preoperative, intraoperative, and postoperative strategies are outlined to reduce the incidence of hyperinflammatory fibrosis and to effectively manage it when present in patients undergoing HDL.
Conclusion:
By understanding the underlying pathophysiology, recognizing procedural risk factors, and implementing targeted prophylactic and therapeutic interventions, surgeons can minimize hyperinflammatory fibrosis and optimize aesthetic outcomes in HDL.
Keywords
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