Thinking Outside the Clock: Using the Whole Genome to Understand the Role of Circadian Rhythms in Human Health

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References

Bouteldja

Penichet

Srivastava

Cermakian

(2024) The circadian system: a neglected player in neurodevelopmental disorders. Eur J Neurosci 60:3858-3890.

Ferguson

Lyall

Ward

Strawbridge

Cullen

Graham

Niedzwiedz

Johnston

KJA

MacKay

Biello

, et al (2018) Genome-wide association study of circadian rhythmicity in 71,500 UK Biobank participants and polygenic association with mood instability. EBioMedicine 35:279-287.

Jones

Lane

Wood

van Hees

Tyrrell

Beaumont

Jeffries

Dashti

Hillsdon

Ruth

, et al (2019) Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms. Nat Commun 10:343.

Landvreugd

Pool

Nivard

Bartels

(2024) Using polygenic scores for circadian rhythms to predict wellbeing, depressive symptoms, chronotype, and health. J Biol Rhythms 39:270-281.

Lane

Qian

Mignot

Redline

Scheer

FAJL

Saxena

(2023) Genetics of circadian rhythms and sleep in human health and disease. Nat Rev Genet 24:4-20.

Zhou

(2021) Genetic prediction of complex traits with polygenic scores: a statistical review. Trends Genet 37:995-1011.

Miguel

Pereira

Barth

de Mendonça Filho

Pokhvisneva

Nguyen

TTT

Garg

Razzolini

Koh

DXP

Gallant

, et al (2019) Prefrontal cortex dopamine transporter gene network moderates the effect of perinatal hypoxic-ischemic conditions on cognitive flexibility and brain gray matter density in children. Biol Psychiatry 86:621-630.