A Balanced Approach To Risk Assessment

Ames, B.N. , MaGaw, R. and Gold, L.S. (1987) Ranking possible carcinogenic hazards. Science, 236:271-280.

Ayesh, R. , Idle, J.R. , Ritchie, J.C. , Crothers, M.J. and Hetzel, M.R. (1984) Metabolic oxidation phenotypes as markers for susceptibility to lung cancer. Nature, 312:169-170.

Harris, C.C. (1989) Interindividual variation among humans in carcinogen metabolism, DNA adduct formation and DNA repair . Carcinogenesis , 10(9):1563-1566.

Hoel, D.G. (1990) Methodological issues of the HERP index. Risk Analysis (in press).

Hoel, D.G. , Haseman, J.K. , Hogan, M.D. , Huff, J.E. and McConnell, E.E. (1988) The impact of toxicity on carcinogenicity studies: Implications for risk assessment. Carcinogenesis, 9:2045-2052.

Hoel, D.G. and Porter, C.J. (1990) Nonlinearity of dose-response functions for carcinogenicity. (In revision)

Kawashima, K. , Shikama, H. , Imoto , K. , Izawa, M. , Naruke, T. , Okabayashi and Nishimura, S. (1988) Close correlation between restruction fragment length polymorphism of the L-MYC gene and metastasis of human lung cancer to the lymph nodes and other organs. Proc. Natl. Acad. Sci . 85:2353-2356.

Lidereau, R. , Escot, C. , Theillet , C. , Champeme, M. , Brunet, M. , Gest, J. and Callahan, R. (1986) High frequency of rare alleles of the human c-Ha-ras-1 proto-oncogene in breast cancer patients. JNCI, 77(3):697-701.

Portier, C. and Kaplan, N. (1989) The variability of safe dose estimates when using complicated models of the carcinogenic process. A case study: Methylene Chloride . Fundamental and Applied Toxicology, 13:(in press).

Ryan, J. , Barker, P.E. , Nesbitt, M.N. and Ruddle, F.H. (1987) KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice. JNCI, 79(6):1351-1357.

Storer, J.B. , Mitchell, T.J. and R.J . (1988) Extrapolation of the relative risk of radiogenic neoplasms across mouse strains and to man. Radiation Research, 114(2):331-353.