Guinea Pig Allergy Tests: an Overview

Adams, R.M. (1983). Occupational Skin Disease. Grune & Stratton, New York.

Andersen, K.E. and Hamann, K. (1983). Is Cytox 3522 (10 methylene-bis-thiocyanate) a human skin sensitizer? Contact Dermatitis 9:186-190.

Andersen, K.E. , Hjorth, N. , Bundgaard, H. and Johansen, M. (1983). Formaldehyde in a hypoallergenic non-woven textile acrylate tape. Contact Dermatitis 9:228.

Andersen, K.E. and Maibach, H.I. (1983). Drugs used topically. In: Allergic Reactions to Drugs. Handbook of Experimental Pharmacology, vol. 63, de Weck A.L. , Bundgaard H. (eds). Berlin, Springer, 313-377.

Andersen, K.E. , Boman, A. , Hamann, K. and Wahlberg, J.E. (1984). Guinea pig maximization tests with formaldehyde releasers. Results from two laboratories. Contact Dermatitis 10:257-266.

Andersen, K.E. and Hamann, K. (1984). How sensitizing is chlorocresol? Allergy tests in guinea pigs versus the clinical experience. Contact Dermatitis 11:11-20.

Andersen, K.E. and Staberg, B. (1985). Quantitation of contact allergy in guinea pigs by measuring changes in skin blood flow and skin fold thickness. Acta Derm. Venereol. (Stockh) 65:37-42.

Andersen, K.E. , Boman, A. , Vlund, Aa. and Wahlberg, J.E. (1985). Induction of formaldehyde contact sensitivity: Dose response relationship in the guinea pig maximization test. Acta Derm. Venereol. (Stockh), in press.

Baer, R.L. and Turk, J.L. (1983). Delayed skin reactions. In: Biochemistry and physiology of the skin. Goldsmith, L.A. (ed). New York, Oxford University Press, 921-937.

Bandmann, H.J. , Calnan, C.D. , Cronin, E. , Fregert, S. , Hjorth, N. , Magnusson, B. , Maibach, H.I. , Malten, K.E. , Meneghini, C.L. , Pirilä, V. and Wilkinson, D.S. (1972). Dermatitis from applied medicaments. Arch. Dermatol. 106:335-337.

Brulos, M.F. , Guillot, J.P. , Martini, M.C. and Cotte, J. (1977). The influence of perfumes on the sensitizing potential of cosmetic bases. I. A technique for evaluating sensitizing potential. J. Soc. Cosmet. Chem. 28:357-365.

Bruynzeel, D.P. , Von Blomberg-Van Der Flier, B.M.E. , Van Ketel, W.G. and Scheper, R.J. (1983). Depression or enhancement of skin reactivity by inflammatory processes in the guinea pig. Int. Arch. Allergy Appl. Immunol. 72:67-70.

Buehler, E.V. (1965). Delayed contact hypersensitivity in the guinea pig. Arch. Dermatol. 91:171-177.

Buehler, E.V. and Griffith, J.F. (1975). Experimental skin sensitization in the guinea pig and man. In: Animal Models in Dermatology. Maibach, H.I. (ed). New York, Churchill Livingstone, 56-66.

Buehler, E.V. (1982). Comment on guinea pig test methods. Fd. Chem. Toxic. 20:494.

Calnan, C.D. (1964). The climate of contact dermatitis. Acta Derm. Venereol. (Stockh) 44:33-43.

Chan, P.K. , Baldwin, R.C. , Parsons, R.D. , Moss, J.N. , Stiratelli, R. , Smith, J.M. and Hayes, A.W. (1983). Kathon biocide: manifestation of delayed contact dermatitis in guinea pigs is dependent on the concentration for induction and challenge. J. Invest. Dermatol. 81:409-411.

Chase, M.W. (1941). Inheritance in guinea pigs of the susceptibility to skin sensitization with simple chemical compounds. J. Exp. Med. 73:711-726.

Chase, M.W. (1952/ 1953). The inheritance of susceptibility to drug allergy in guinea pigs. Trans. NY Acad. Sci. Series II 15:79-82.

Christensen, O.B. , Christensen, M.B. and Maibach, H.I. (1984). Effect of vehicle on elicitation of DNCB contact allergy in the guinea pig. Contact Dermatitis 10:166-169.

Christoffersen, J. (1984). Skin diseases in Denmark. Thesis. Danish Institute of Clinical Epidemiology. Copenhagen .

Chung, C.W. and Giles, A.L. (1977). Sensitization potentials of methyl, ethyl, and n-butyl methacrylates and mutual cross-sensitivity in guinea pigs. J. Invest. Dermatol. 68:187-190.

Cronin, E. (1980). Contact Dermatitis. Edinburgh , Churchill Livingstone.

Draize, J.H. (1959). Dermal toxicity. Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics. The Association of Food and Drug Officials in the United States, Austin, Texas , 46.

Dupuis, G. and Benezra, C. (1982). Allergic contact dermatitis to simple chemicals . New York, Marcel Dekker Inc.

Eiermann, H.J. , Larsen, W. , Maibach, H.I. and Taylor, J.S. (1982). Prospective study of cosmetic reactions 1977-1980 . J. Am. Acad. Dermatol. 6:909-917.

Epstein, W.L. , Byers, V.S. and Baer, H. (1981). Induction of persistent tolerance to urishiol in humans. J. Allergy Clin. Immunol. 68:20-25.

Fahr, H. , Noster, U. and Schulz, K.H. (1976). Comparison of guinea pig sensitization methods . Contact Dermatitis 2:335-339.

Fda. (1978). Good laboratory practice for nonclinical laboratory studies. Fed. Reg. 32,427.

Feldman, R.J. and Maibach, H.I. (1965). Penetration of 14C-hydrocortisone through normal skin. Arch. Dermatol. 91:661-666.

Feldman, R.J. and Maibach, H.I. (1967). Regional variation in percutaneous penetration of 14C-cortisone in man. J. Invest. Dermatol. 48:181-183.

Fregert, S. , Gruvberger, B. and Sandahl, E. (1979). Reduction of chromate in cement by iron sulfate . Contact Dermatitis 5:39-42.

Godfrey, H.P. and Baer, H. (1971a). The effect of physical and chemical properties of the sensitizing substance on the induction and elicitation of delayed contact sensitivity. J. Immunol. 106:431-441.

Godfrey, H.P. and Baer, H. (1971b). The effect of excision of the site of application on the induction of delayed contact sensitivity. J. Immunol. 197:1643-1646.

Goodwin, B.F.J. , Crewel, R.W.R. and Johnson, A.W. (1981). A comparison of three guinea pig sensitization procedures for the detection of 19 reported human contact sensitizers. Contact Dermatitis 7:248-258.

Griffith, J.F. and Buehler, E.V. (1977). Prediction of skin irritancy and sensitizing potential by testing with animals and man. In: Cutaneous Toxicity. Drill, V.A. , Lazar, P. (eds.). New York, Academic Press, 155-173.

Guillot, J.P. , Gonnet, J.F. , Clement, C. and Faccini, J.M. (1983). Comparative study of methods chosen by the Association Francaise de Normalisation (AFNOR) for evaluating sensitizing potential in the albino guinea pig. Fd. Chem. Toxicol. 21:795-805.

Henderson, C.R. and Riley, E.C. (1945). Certain statistical considerations in patch testing . J. Invest. Dermatol. 6:227-232.

Hjorth, N. (1966). Primula dermatitis. Trans. St. John's Hosp. Dermatol. Soc. 52:207-219.

Hjorth, N. (1982). The Allergens. In: Occupational and Industrial Dermatology. Maibach, H.I. , Gellin, G.A. (eds). London, Year Book Medical Publishers Inc., 29-33.

Hjorth, N. (1983). Diagnostic patch testing. In: Dermatotoxicology. Marzuli, F.N. , Maibach, H.I. (eds). 2 ed. Washington, Hemisphere Publ. Corp. 267-277.

Hjorth, N. and Thomsen, K. (1968). Difference in sensitizing capacity of neomycin in creams and in ointments. Br. J. Dermatol. 80:163-169.

Hjorth, N. and Trolle Lassen, C. (1963). Skin reactions to ointment bases. Trans. St. John's Hosp. Dermatol. Soc. 49:127-140.

Hvding, G. (1970). Cement eczema and chromium allergy. An epidemiological investigation. Thesis, Bergen, Norway.

Johansen, M. and Bundgaard, H. (1981). Kinetics of formaldehyde release from the cosmetic preservative Germall 115. Arch. Pharm. Chem. Sci. 88:117-122.

Johnson, M.-L.T. , Burdick, A.E. , Johnson, K.G. , Klarman, H.E. , Krasner, M. , McDowell, A.J.M. and Roberts, J. (1979). Prevalence, morbidity and cost of dermatological diseases. J. Invest. Dermatol. 73:395-401.

Jordan, W.P. , Sherman, W.T. and King. S.E. (1979). Threshold response in formaldehyde-sensitive subjects . J. Am. Acad. Dermatol. 1:44-48.

Kero, M. and Hannuksela, M. (1980). Guinea pig maximization test, open epicutaneous test, and chamber test in induction of delayed contact hypersensitivity. Contact Dermatitis 6:341-344.

Klecak, G. (1983). Indentification of contact allergens: Predictive tests in animals. In: Dermatotoxicology. Marzulli, F.N. , Maibach, H.I. (eds). Washington, Hemisphere Publ. Corp. 193-236.

Klecak, G. , Geleick, H. and Frey, J.R. (1977). Screening of fragrance materials for allergenicity in the guinea pig. I. Comparison of four testing methods. J. Soc. Cosmet. Chem. 28:53-64.

Kligman, A.M. (1966). The identification of contact allergens by human assay. III. The maximization test—a procedure for screening and rating contact sensitizers. J. Invest. Dermatol. 47:393-409.

Landsteiner, K. and Jacobs, I. (1935). Studies on the sensitization of animals with simple chemical compounds. J. Exp. Med. 61:643-656.

Landsteiner, K. and Jacobs, I. (1936). Studies on the sensitization of animals with simple chemical compounds. II. J. Exp. Med. 64:625-639.

Ljungren, B. and Möller, H. (1972). Eczematous contact allergy to chlorhexidine. Acta Derm. Venereol. (Stockh) 52:308-310.

Lowney, E.D. (1970). Dermatologic implications of immunologic unresponsiveness . J. Invest. Dermatol. 54:355-364.

Macher, E. and Chase, M.W. (1969). Studies on the sensitization of animals with simple chemical compounds. XII. The influence of excision of allergenic depots on onset of delayed hypersensitivity and tolerance. J. Exp. Med. 129:103-121.

Magnusson, B. and Kligman, A.M. (1970). Allergic contact dermatitis in the guinea pig . Springfield, Ill., Charles C. Thomas.

Magnusson, B. , Fregert, S. and Wahlberg, J.E. (1982). Determining the allergic contact potential of chemicals. In: Occupational and Industrial Dermatology. Maibach, H. I. , Gellin, G.A. (eds). Chicago, Year Book Medical Publ. 173-185.

Maguire, Jr., H.C. and Chase, M.W. (1972). Studies on the sensitization of animals with simple chemical compounds. XIII. J. Exp. Med. 135:357-375.

Maguire, Jr., H.C. (1974). Alteration in the acquisition of delayed hypersensitivity with adjuvant in the guinea pig. Monogr. Allergy 8:13-26.

Maguire, Jr., H.C. (1975). Estimation of the allergenicity of prospective human contact sensitizers in the guinea pig. In: Animal Models in Dermatology. Maibach, H.I. (ed). London, Churchill Livingstone, 67-75.

Maibach, H.I. and Prystowsky, S.D. (1977). Glutaraldehyde (pentanedial) allergic contact dermatitis. Arch. Dermatol. 113:170-171.

Maibach, H.I. (1981). The ESS-excited skin syndrome (alias the "angry back"). In: New Trends in Allergy. Ring, J. , Burg, G. (eds). Berlin, Springer 208-221.

Mali, J.-W.H. , Malten, K. and Van Neer, F.C.J. (1966). Allergy to chromium. Arch. Dermatol. 93:41-44.

Marzulli, F.N. and Maibach, H.I. (1974). The use of graded concentrations in studying skin sensitizers: Experimental contact sensitization in man. Fd. Cosmet. Toxicol. 12:219-227.

Marzulli, F.N. and Maibach, H.I. (1980). Further studies of effects of vehicles and elicitation concentration in experimental contact sensitization testing in humans. Contact Dermatitis 6:131-133.

Marzulli, F.N. and Maguire, Jr., H.C. (1983). Validation of guinea pig tests for skin hypersensitivity. In: Dermatotoxicology. Marzulli, F.N. , Maibach, H.I. (eds). Washington, Hemisphere Publ. Corp. 237-250.

Marzulli, F.N. and Maibach, H.I. (1983a). Dermatotoxicology. Washington , Hemisphere Publ. Corp.

Marzulli, F.N. and Maibach, H.I. (1983b). Contact allergy: Predictive testing in humans . In: Dermatotoxicology. Marzulli, F.N. , Maibach, H.I. (eds.). Washington, Hemisphere Publ. Corp. 279-299.

Maurer, T. , Thomann, P. , Weirich, E.G. and Hess, R. (1975). The optimization test in the guinea pig. A method for the predictive evaluation of the contact allergenicity of chemicals. Agents and Actions 5:174-179.

Maurer, T. Thomann, P. , Weirich, E.G. and Hess, R. (1978). Predictive evaluation in animals of the contact allergenic potential of medically important substances. I. Comparison of different methods of inducing and measuring cutaneous sensitization. Contact Dermatitis 4:321-333.

Maurer, T. , Weirich, E.G. and Hess, R. (1980). The optimization test in the guinea pig in relation to other predictive sensitization methods. Toxicology 15:163-171.

Maurer, T. (1983). Contact and Photocontact Allergens. New York, Marcel Dekker, Inc., 74.

Menné, T. , Borgan, O. and Green, A. (1982). Nickel allergy and hand dermatitis in a stratified sample of the Danish female population: An epidemiological study including a statistic appendix. Acta Derm. Venereol. ( Stockh) 62:35-41.

Menné, T. and Holm, N.V. (1983a). Hand eczema in nickel-sensitive female twins. Genetic predisposition and environmental factors. Contact Dermatitis 9:289-296.

Menné, T. and Holm, N.V. (1983b). Nickel allergy in a female twin population. Int. J. Dermatol. 2:22-28.

Mitchell, J.C. and Maibach, H.I. (1982). The angry back syndrome—the excited skin syndrome. Semin. Dermatol. 1:9-13.

Moller, H. (1984). Attempts to induce contact allergy to nickel in the mouse. Contact Dermatitis 10:65-68.

Nater, J.P. and Hoedemaeker, P.J. (1976). Histological differences between irritant and allergic patch test reactions in man. Contact Dermatitis 2:247-253.

Oecd. (1981). Organization for Economic Cooperation and Development. OECD Guidelines for Testing of Chemicals. Skin Sensitization. OECD Publications and Information Center , Suite 1207, 1750 Pennsylvania Ave., Washington, D.C. 20006.

Parker, D. , Sommer, G. and Turk, J.L. (1975). Variation in guinea pig responsiveness. Cell. Immunol. 18:233-238.

Polak, L. , Barnes, J.M. and Turk, J.L. (1968). The genetic control of contact sensitization to inorganic metal compounds in guinea pigs. Immunology 14:707-711.

Polak, L. and Turk, J.L. (1968). Studies on the effect of systemic administration of sensitizers in guinea pigs with contact sensitivity to inorganic metal compounds. I. The induction of immunological unresponsiveness in already sensitized animals. Clin. Exp. Immunol. 3:245-251.

Polak, L. (1980). Immunological aspects of contact sensitivity. Monographs in Allergy. Vol. 15. Basel, Karger, 43.

Polak, L. and Scheper, R.J. (1981). In vitro DNA synthesis in lymphocytes from guinea pigs epicutaneously sensitized with DNCB. J. Invest. Dermatol. 76:133-136.

Prince, H.N. and Prince, T.G. (1977). Comparative guinea pig assays for contact hypersensitivity . Cosmet. Toilet. 92:53-58.

Ritz, H.L. , Connor, D.S. and Sauter, E.D. (1975). Contact sensitization of guinea pigs with unsaturated and halogenated sultones. Contact Dermatitis 1:349-358.

Ritz, H.L. and Buehler, E.V. (1980). Planning, conduct and interpretation of guinea pig sensitization patch tests. In: Current Concepts in Cutaneous Toxicity. Drill, V.A. , Lazar, P. (eds). New York, Academic Press, 25-40.

Roberts, D.W. and Williams, D.L. (1982). The derivaton of quantitative correlations between skin sensitization and physico-chemical parameters for alkylating agents, and their application to experimental data for sultones. J. Theor. Biol. 99:807-825.

Roberts, D.W. , Goodwin, B.F.J. , Williams, D.L. , Jones, K. , Johnson, A.W. and Alderson, J.C.E. (1983). Correlations between skin sensitization potential and chemical reactivity for p-nitrobenzyl compounds. Fd. Chem. Toxicol. 21:811-813.

Rudzki, E. and Zakrzewski, Z. (1975). Incidence of contact sensitivity to topically applied drugs as compared with the frequency of their prescription. Contact Dermatitis 1:249-250.

Sato, Y. , Katsumura, Y. , Ichikawa, H. , Kobayashi, T. , Kozuka, T. , Morikawa, F. and. Ohta, S. (1981). A modified technique of guinea pig testing to identify delayed hypersensitivity allergens. Contact Dermatitis 7:225-237.

Scheynius, A. , Fischer, T. , Forsum, U. and Klareskog, L. (1984). Phenotypic characterization in situ of inflammatory cells in allergic and irritant contact dermatitis in man. Clin. Exp. Immunol. 55:81-90.

Sharp, D.W. (1978). The sensitization potential of some perfume ingredients tested using a modified Draize procedure. Toxicology 9:261-271.

Silberberg, I. (1973). Apposition of mononuclear cells to Langerhans cells in contact allergic reactions. An ultrastructural study. Acta Derm. Venereol. (Stockh) 53:1-12.

Skog, E. (1965). Sensitization to p-phenylenediamine. Arch Dermatol. 92:276-280.

Stampf, J.L. , Benezra, C. , Klecak, G. , Geleick, H. , Schultz, K.H. and Hausen, B. (1982). The sensitizing capacity of helenin, and of two of its main constituents, the sesquiterpene lactones alantolactone and isoalantholactone: a comparison of epicutaneous and intradermal sensitizing methods in different strains of guinea pig. Contact Dermatitis 8:16-24.

Steinberg, M. , Akers, W.A. , Weeks, M. , McCreesh, A.H. and Maibach, H. (1975). A comparison of test techniques based on rabbit and human skin responses to irritants with recommendations regarding the evaluation of mildly or moderately irritating compounds. In: Animal Models in Dermatology. Maibach, H.I. (ed). New York, Churchill Livingstone, 1-11.

Stevens, M.A. (1967). Use of the albino guinea-pig to detect the skin-sensitizing ability of chemicals. Br. J. Ind. Med. 24:189-202.

Stingl, G. , Katz, S.I. , Shevach, A.M. , Rosenthal, A.S. and Green, I. (1978). Analogous functions of macrophages and Langerhans cells in the initiation of the immune response. J. Invest. Dermatol. 71:59-64.

Takano, S. , Yamanaka, M. and Okamoto, K. (1983). Allergens of lanolin: Parts I and II. J. Soc. Cosmet. Chem. 34:99-125.

Tsuchiya, S. , Kondo, M. , Okamoto, K. and Takase, Y. (1982). Studies on contact hypersensibility in the guinea pig. The cumulative contact enhancement test. Contact Dermatitis 8:246-255.

Turk, J.L. and Parker, D. (1977). Sensitization with Cr, Ni, and Zr salts and allergic type granuloma formation in the guinea pig. J. Invest. Dermatol. 68:341-345.

Vadas, M.A. , Miller, J.F.A.P. , Whitelaw, A.M. and Gamble, J.R. (1977). Regulation by the H-2 gene complex of delayed type hypersensitivity. Immunogenetics 4:137-153.

Van Der Walle, H.B. , Klecak, G. , Geleick, H. and Benzink, T. (1982). Sensitizing potential of 14 mono(meth)acrylates in guinea pig. Contact Dermatitis 8:223-235.

Voss, J.G. (1958). Skin sensitization by mercaptans of low molecular weight. J. Invest. Dermatol. 31:273-279.

Weil, C.S. and Scala, R.A. (1971). Study of intra- and inter-laboratory variability in the results of rabbit eye and skin irritation tests. Tox. Appl. Pharmacol. 19:276-360.

Wester, R.C. and Maibach, H.I. (1983). Cutaneous pharmaco-kinetics: 10 steps to percutaneous absorption. Drug Metabolism Reviews 14:169-205.

Wilkinson, J.D. , Hambly, E.M. and Wilkinson, D.S. (1980). Comparison of patch test results in two adjacent areas of England. II. Medicaments. Acta Derm. Venereol. (Stockh) 60:245-249.

Ziegler, V. (1977). Der tierexperimentelle Nachweis allergener Eigenschaften von Industrieprodukten. Dermatol. Monatsschr. 163:387-391.