Workplace hydrogen sulphide intoxication – What an occupational physician should know

Austigard ÅD (2024) Hydrogen Sulphide Risk Characteristics in Wastewater Work. PhD Thesis, Norwegian University of Science and Technology, Trondheim, Norway. Available at. https://hdl.handle.net/11250/3150615 (accessed [1st December 2025])

Brenner M (2010) Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring. Journal of Biomedical Optics 15(1): 017001.

Fujita Y Fujino Y Onodera M , et al. (2011) A fatal case of acute hydrogen sulfide poisoning caused by hydrogen sulfide: hydroxocobalamin therapy for acute hydrogen sulfide poisoning. Journal of Analytical Toxicology 35(2): 119–123.

Haouzi P Sonobe T Judenherc-Haouzi A (2016) Developing effective countermeasures against acute hydrogen sulfide intoxication: challenges and limitations. Annals of the New York Academy of Sciences 1374(1): 29–40.

Haouzi P Sonobe T Judenherc-Haouzi A (2020) Hydrogen sulfide intoxication induced brain injury and methylene blue. Neurobiology of Disease 133: 104474.

Henretig FM Kirk MA McKay CA (2019) Hazardous chemical emergencies and poisonings. The New England Journal of Medicine 380(17): 1638–1655.

Jiang J Chan A Ali S , et al. (2016) Hydrogen sulfide—mechanisms of toxicity and development of an antidote. Scientific Reports 6: 20831.

Jones K (2014) Case studies of hydrogen sulphide occupational exposure incidents in the UK. Toxicology Letters 231(3): 374–377.

Kage S Nagata T Kudo K , et al. (1997) The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases. International Journal of Legal Medicine 110(4): 220–222.

Oesterhelweg L Püschel K (2008) ‘Death may come on like a stroke of lightening…’: Phenopenological and morphological aspects of fatal H2S intoxication. International Journal of Legal Medicine 122(2): 101–107.

Quist A Johnston J (2024) Respiratory and nervous system effects of a hydrogen sulfide crisis in Carson, California. Science of the Total Environment 906: 167480.

Shen Y Zhao G Lin J , et al. (2024) Case series and clinical analysis of acute hydrogen sulfide poisoning: experience from 10 cases at a hospital in Zhoushan. Toxicology and Industrial Health, Epub ahead of print. DOI: 10.1177/07482337241308388.

Stine RJ (1976) Hydrogen sulfide intoxication. Annals of Internal Medicine 85(6): 756–758. DOI: 10.7326/0003-4819-85-6-756.

Tang D Tian N Cai J , et al. (2022) Analysis of CT and MR imaging features of the brain in patients with hydrogen sulfide poisoning based on clinical symptom grading. BMC Neurology 22(1): 413.

Wang R Fan Z Wei Z , et al. (2022) Decomposition kinetics and postmortem production of hydrogen sulfide and its metabolites. Forensic Science International 340: 111426.