Associations Among Loneliness,Purpose in Life and Subjective Cognitive Decline in Ethnoracially Diverse Older Adults Living in the United States

Abstract

Subjective cognitive decline (SCD), which precedes Mild Cognitive Impairment and dementia, may be affected by purpose in life (PiL) and loneliness in older adults. We investigated associations among PiL, loneliness, and SCD in US Latino (n = 126), Black (n = 74), Asian (n = 33), and White (n = 637) adults. Higher PiL predicted lower SCD in all groups (p-values < .012), except Black participants. Lower loneliness predicted lower SCD in Latino and White groups (p-values < .05), and PiL moderated this association in White adults. PiL and loneliness may play important roles in cognitive decline. Differential predictors of SCD suggest differential targets for preventing cognitive decline and dementia across ethnoracial groups.

Keywords

purpose in life subjective cognitive decline mild cognitive impairment social isolation Latinos loneliness

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References

Akhter-Khan

S. C.

Tao

Ang

T. F. A.

Itchapurapu

I. S.

Alosco

M. L.

Mez

Piers

R. J.

Steffens

D. C.

Qiu

W. Q.

(2021). Associations of loneliness with risk of Alzheimer’s disease dementia in the Framingham Heart Study. Alzheimer’s & Dementia, 17(10), 1619–1627. https://doi.org/10.1002/alz.12327

Alzheimer’s Association . (2021). 2021 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia, 17(3), 327–406. https://www.alz.org/alzheimers-dementia/facts-figures

American Psychological Association (2020). Publication manual of the American psychological association (7th ed.). American Psychological Association.

Babulal

G. M.

Torres

V. L.

Acosta

Agüero

Aguilar-Navarro

Amariglio

Ussui

J. A.

Baena

Bocanegra

Brucki

S. M. D.

Bustin

Cabrera

D. M.

Custodio

Diaz

M. M.

Peñailillo

L. D.

Franco

Gatchel

J. R.

Garza-Naveda

A. P.

González Lara

Quiroz

Y. T.

(2021). The impact of COVID-19 on the well-being and cognition of older adults living in the United States and Latin America. EClinicalMedicine, 35, 100848. https://doi.org/10.1016/j.eclinm.2021.100848

Boss

Kang

D.-H.

Branson

(2015). Loneliness and cognitive function in the older adult: A systematic review. International Psychogeriatrics, 27(4), 541–553. https://doi.org/10.1017/S1041610214002749

Boyle

P. A.

Barnes

L. L.

Buchman

A. S.

Bennett

D. A.

(2009). PiL is associated with mortality among community-dwelling older persons. Psychosomatic Medicine, 71(5), 574–579. https://doi.org/10.1097/PSY.0b013e3181a5a7c0

Boyle

P. A.

Buchman

A. S.

Barnes

L. L.

Bennett

D. A.

(2010). Effect of a Purpose in Life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. Archives of General Psychiatry, 67(3), 304–310. https://doi.org/10.1001/archgenpsychiatry.2009.208

Burns

S. P.

Mueller

Magwood

White

B. M.

Lackland

Ellis

(2019). Racial and ethnic differences in post-stroke subjective cognitive decline exist. Disability and Health Journal, 12(1), 87–92. https://doi.org/10.1016/j.dhjo.2018.08.005

Estrella

M. L.

Durazo-Arvizu

R. A.

Gallo

L. C.

Tarraf

Isasi

C. R.

Perreira

K. M.

Zeng

Marquine

M. J.

Lipton

R. B.

González

H. M.

Daviglus

M. L.

Lamar

(2021). Psychosocial factors associated with cognitive function among middle-aged and older Hispanics/Latinos: The Hispanic community health study/study of Latinos and its sociocultural ancillary study. Journal of Alzheimer’s Disease, 79(1), 433–449. https://doi.org/10.3233/JAD-200612

10.

Farias

S. T.

Mungas

Harvey

D. J.

Simmons

Reed

B. R.

DeCarli

(2011). The measurement of everyday cognition: Development and validation of a short form of the Everyday Cognition scales. Alzheimer’s & Dementia, 7(6), 593–601. https://doi.org/10.1016/j.jalz.2011.02.007

11.

Farias

S. T.

Mungas

Reed

B. R.

Cahn-Weiner

Jagust

Baynes

DeCarli

(2008). The measurement of everyday cognition (ECog): Scale development and psychometric properties. Neuropsychology, 22(4), 531–544. https://doi.org/10.1037/0894-4105.22.4.531

12.

Faustin

Masurkar

A. V.

(2020). Differences in the characteristics, neuropsychiatric comorbidities, and psychometric features of subjective cognitive decline in Hispanics versus non Hispanic Whites: Examining subjective cognitive decline in diverse, ethnoracial populations. Alzheimer’s & Dementia, 16(S6), Article e040431. https://doi.org/10.1002/alz.040431

13.

George

K. M.

Lutsey

P. L.

Kucharska-Newton

Palta

Heiss

Osypuk

Folsom

A. R.

(2020). Life-course individual and neighborhood socioeconomic status and risk of dementia in the atherosclerosis risk in communities neurocognitive study. American Journal of Epidemiology, 189(10), 1134–1142. https://doi.org/10.1093/aje/kwaa072

14.

Gierveld

J. D. J.

Tilburg

T. V.

(2006). A 6-item scale for overall, emotional, and social loneliness: Confirmatory tests on survey data. Research on Aging, 28(5), 582–598. https://doi.org/10.1177/0164027506289723

15.

Gupta

(2021). Racial and ethnic disparities in subjective cognitive decline: A closer look, United States, 2015–2018. BMC Public Health, 21(1), 1173. https://doi.org/10.1186/s12889-021-11068-1

16.

Harwood

Barker

Ownby

Duara

(1998). Memory complaints in the elderly: A comparative analysis of informant and subject reports among Hispanics and White non-Hispanics. Clinical Gerontologist: The Journal of Aging and Mental Health, 18(3), 56–60. https://psycnet.apa.org/record/1998-01325-006

17.

Heser

Kleineidam

Wiese

Oey

Roehr

Pabst

Kaduszkiewicz

van den Bussche

Brettschneider

König

H.-H.

Weyerer

Werle

Fuchs

Pentzek

Mösch

Bickel

Maier

Scherer

Riedel-Heller

S. G.

Wagner

(2019). Subjective cognitive decline may be a stronger predictor of incident dementia in women than in men. Journal of Alzheimer’s Disease, 68(4), 1469–1478. https://doi.org/10.3233/JAD-180981

18.

Holmen

Langballe

E. M.

Midthjell

Holmen

T. L.

Fikseaunet

Saltvedt

Tambs

(2013). Gender differences in subjective memory impairment in a general population: The HUNT study, Norway. BMC Psychology, 1(1), 1–9. https://doi.org/10.1186/2050-7283-1-19

19.

Jackson

J. D.

Rentz

D. M.

Aghjayan

S. L.

Buckley

R. F.

Meneide

T.-F.

Sperling

R. A.

Amariglio

R. E.

(2017). Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons. Age and Ageing, 46(6), 988–993. https://doi.org/10.1093/ageing/afx077

20.

Jaimes

Londono

Halpern

A. C.

(2013). The term Hispanic/Latino: A note of caution. JAMA Dermatology, 149(3), 274–275. https://doi.org/10.1001/jamadermatol.2013.1304

21.

Jang

Choi

E. Y.

Franco

Park

N. S.

Chiriboga

D. A.

Kim

M. T.

(2021). Racial and ethnic differences in cognitive health appraisals: A comparison of non-Hispanic White, non-Hispanic Black, and Hispanic older adults. Aging & Mental Health, 26(3), 519–525. https://doi.org/10.1080/13607863.2021.1899132

22.

Jessen

Amariglio

R. E.

Buckley

R. F.

van der Flier

W. M.

Han

Molinuevo

J. L.

Rabin

Rentz

D. M.

Rodriguez-Gomez

Saykin

A. J.

Sikkes

S. A. M.

Smart

C. M.

Wolfsgruber

Wagner

(2020). The characterisation of subjective cognitive decline. The Lancet Neurology, 19(3), 271–278. https://doi.org/10.1016/s1474-4422(19)30368-0

23.

Kang

Cosme

Pei

Pandey

Carreras-Tartak

Falk

E. B.

(2021). PiL, loneliness, and protective health behaviors during the COVID-19 pandemic. The Gerontologist, 61(6), 878–887. https://doi.org/10.1093/geront/gnab081

24.

Kelly

M. E.

Duff

Kelly

McHugh Power

J. E.

Brennan

Lawlor

B. A.

Loughrey

D. G.

(2017). The impact of social activities, social networks, social support and social relationships on the cognitive functioning of healthy older adults: A systematic review. Systematic Reviews, 6(1), 259. https://doi.org/10.1186/s13643-017-0632-2

25.

Kline

R. B.

(2016). Principles and practice of structural equation modeling (4th ed.). Guilford Publications.

26.

Lara

Caballero

F. F.

Rico Uribe

L. A.

Olaya

Haro

J. M.

Ayuso Mateos

J. L.

Miret

(2019). Are loneliness and social isolation associated with cognitive decline? International Journal of Geriatric Psychiatry, 34(11), 1613–1622. https://doi.org/10.1002/gps.5174

27.

Lewis

N. A.

Turiano

N. A.

Payne

B. R.

Hill

P. L.

(2017). PiL and cognitive functioning in adulthood. Aging, Neuropsychology, and Cognition, 24(6), 662–671. https://doi.org/10.1080/13825585.2016.1251549

28.

Liu

Zhang

Burgard

S. A.

Needham

B. L.

(2019). Marital status and cognitive impairment in the United States: Evidence from the national health and aging trends study. Annals of Epidemiology, 38(e22), 28–34. https://doi.org/10.1016/j.annepidem.2019.08.007

29.

Luhmann

Hawkley

L. C.

(2016). Age differences in loneliness from late adolescence to oldest old age. Developmental Psychology, 52(6), 943–959. https://doi.org/10.1037/dev0000117

30.

Martinez

J. E.

Pardilla-Delgado

Guzmán-Vélez

Vila-Castelar

Amariglio

Gatchel

Aguirre-Acevedo

D. C.

Bocanegra

Baena

Henao

Tirado

Muñoz

Giraldo-Chica

Lopera

Quiroz

Y. T.

(2021). Subjective cognitive decline and its relation to verbal memory and sex in cognitively unimpaired individuals from a Colombian cohort with autosomal-dominant Alzheimer’s disease. Journal of the International Neuropsychological Society, 28(6), 541–549. https://doi.org/10.1017/S1355617721000801

31.

Montejo

Crespo

D. P.

Pedrero-Pérez

Montenegro-Peña

(2020). Subjective cognitive decline: Mental health, loneliness, pain and quality of life: Poblational study. Journal of Aging Science, 8(1), 218. https://doi.org/10.35248/2329-8847.20.08.218

32.

Mwilambwe-Tshilobo

Chong

Ferguson

M. A.

Misic

Burrow

A. L.

Leahy

R. M.

Spreng

R. N.

(2019). Loneliness and meaning in life are reflected in the intrinsic network architecture of the brain. Social cognitive and affective neuroscience, 14(4), 423–433. https://doi.org/10.1093/scan/nsz021

33.

Myhre

J. W.

Mehl

M. R.

Glisky

E. L.

(2016). Cognitive benefits of online social networking for healthy older adults. The Journals of Gerontology Series B, 72(5), 752–760. https://doi.org/10.1093/geronb/gbw025

34.

Neville

Adams

Montayre

Larmer

Garrett

Stephens

Alpass

(2018). Loneliness in men 60 years and over: The association with Purpose in Life. American Journal of Men’s Health, 12(4), 730–739. https://doi.org/10.1177/1557988318758807

35.

Norton

D. J.

Amariglio

Protas

Chen

Aguirre-Acevedo

D. C.

Pulsifer

Castrillon

Tirado

Munoz

Tariot

Langbaum

J. B.

Reiman

E. M.

Lopera

Sperling

R. A.

Quiroz

Y. T.

(2017). Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology, 89(14), 1464–1470. https://doi.org/10.1212/WNL.0000000000004533

36.

Peterson

R. L.

Carvajal

S. C.

McGuire

L. C.

Fain

M. J.

Bell

M. L.

(2019). State inequality, socioeconomic position and subjective cognitive decline in the United States. SSM - Population Health, 7, 100357. https://doi.org/10.1016/j.ssmph.2019.100357

37.

Pinquart

Sorensen

(2010). Influences on loneliness in older adults: A meta-analysis. Basic and Applied Social Psychology, 23(4), 245–266. https://doi.org/10.1207/S15324834BASP2304_2

38.

Pitkala

K. H.

Routasalo

Kautiainen

Sintonen

Tilvis

R. S.

(2011). Effects of socially stimulating group intervention on lonely, older people’s cognition: A randomized, controlled trial. The American Journal of Geriatric Psychiatry, 19(7), 654–663. https://doi.org/10.1097/JGP.0b013e3181f7d8b0

39.

Rodrıguez

Ayers

Weiss

E. F.

Verghese

(2021). Cross-cultural comparisons of subjective cognitive complaints in a diverse primary care population. Journal of Alzheimer’s Disease, 81(2), 545–555. https://doi.org/10.3233/jad-201399

40.

Röhr

Pabst

Riedel-Heller

S. G.

Jessen

Turana

Handajani

Y. S.

Brayne

Matthews

F. E.

Stephan

B. C. M.

Lipton

R. B.

Katz

M. J.

Wang

Guerchet

Preux

P.-M.

Mbelesso

Ritchie

Ancelin

M.-L.

Carrière

Guaita

A.,

Sachdev

P. S.

(2020). Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: A COSMIC study. Alzheimer’s Research & Therapy, 12(1), 1–14. https://doi.org/10.1186/s13195-020-00734-y

41.

Ryff

(1989). Happiness is everything, or is it? Explorations on the meaning of psychological well-being. Journal of Personality and Social Psychology, 57(6), 1069–1081. https://doi.org/10.1037/0022-3514.57.6.1069

42.

Studart Neto

Nitrini

(2016). Subjective cognitive decline: The first manifestations of Alzheimer’s disease? Dementia & Neuropsychologia, 10(3), 170–177. https://doi.org/10.1590/S1980-5764-2016DN1003002

43.

Sundermann

E. E.

Edmonds

E. C.

Delano-Wood

Galasko

D. R.

Salmon

D. P.

Rubin

L. H.

Bondi

M. W.

& Alzheimer’s Disease Neuroimaging Initiative . (2018). Sex influences the accuracy of subjective memory complaint reporting in older adults. Journal of Alzheimer’s Disease, 61(3), 1163–1178. https://doi.org/10.3233/JAD-170425

44.

Sundström

Adolfsson

A. N.

Nordin

Adolfsson

(2020). Loneliness increases the risk of all-cause dementia and Alzheimer’s disease. The Journals of Gerontology: Series B, 75(5), 919–926. https://doi.org/10.1093/geronb/gbz139

45.

Sutin

A. R.

Stephan

Luchetti

Terracciano

(2020). Loneliness and risk of dementia. The Journals of Gerontology: Series B, 75(7), 1414–1422. https://doi.org/10.1093/geronb/gby112

46.

Wingo

A. P.

Wingo

T. S.

Fan

Bergquist

Alonso

Marcus

Levey

A. I.

Lah

J. J.

(2020). Purpose in Life is a robust protective factor of reported cognitive decline among late middle-aged adults: The Emory Healthy Aging Study. Journal of Affective Disorders, 263(3), 310–317. https://doi.org/10.1016/j.jad.2019.11.124

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